Marijuana and Pain: Is There a Real Benefit?

Today we will be discussing cannabis as it relates to chronic pain and neurological disorders, covering some of the most recent scientific research on the matter, and how this information pertains to questions regarding cannabis and their symptoms.

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1.A user’s guide to cannabinoid therapies in oncology.
Maida V, Daeninck PJ.
Curr Oncol. 2016 Dec;23(6):398-406. doi: 10.3747/co.23.3487. Review.
PMID: 28050136 [PubMed] Free PMC Article
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2.Evolution of multiple sclerosis spasticity-associated symptoms: latest data.
Flachenecker P.
Neurodegener Dis Manag. 2016 Dec;6(6s):9-12.
PMID: 27874495 [PubMed – in process]
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3.Cannabinoid Buccal Spray for Chronic Non-Cancer or Neuropathic Pain: A Review of Clinical Effectiveness, Safety, and Guidelines [Internet].
Ottawa (ON): Canadian Agency for Drugs and Technologies in Health; 2016 Sep 21.
PMID: 27831665 [PubMed] Free Books & Documents
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4.Targeting the Endocannabinoid System in Psychiatric Illness.
Katzman MA, Furtado M, Anand L.
J Clin Psychopharmacol. 2016 Dec;36(6):691-703.
PMID: 27811555 [PubMed – in process]
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5.Medical Marijuana: Just the Beginning of a Long, Strange Trip?
Ciccone CD.
Phys Ther. 2016 Sep 22. [Epub ahead of print]
PMID: 27660328 [PubMed – as supplied by publisher]
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6.Tetrahydrocannabinol:Cannabidiol Oromucosal Spray for Multiple Sclerosis-Related Resistant Spasticity in Daily Practice.
Vermersch P, Trojano M.
Eur Neurol. 2016;76(5-6):216-226.
PMID: 27732980 [PubMed – in process]
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7.Cannabinoids: Medical implications.
Schrot RJ, Hubbard JR.
Ann Med. 2016;48(3):128-41. doi: 10.3109/07853890.2016.1145794. Review.
PMID: 26912385 [PubMed – indexed for MEDLINE]
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8.[Efficacy, tolerability and safety of cannabinoids for chronic neuropathic pain: A systematic review of randomized controlled studies].
Petzke F, Enax-Krumova EK, Häuser W.
Schmerz. 2016 Feb;30(1):62-88. doi: 10.1007/s00482-015-0089-y. German.
PMID: 26830780 [PubMed – in process]
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9.Efficacy, tolerability and safety of cannabinoids in chronic pain associated with rheumatic diseases (fibromyalgia syndrome, back pain, osteoarthritis, rheumatoid arthritis): A systematic review of randomized controlled trials.
Fitzcharles MA, Baerwald C, Ablin J, Häuser W.
Schmerz. 2016 Feb;30(1):47-61. doi: 10.1007/s00482-015-0084-3.
PMID: 26767993 [PubMed – in process]
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10.Medical use of cannabis products: Lessons to be learned from Israel and Canada.
Ablin J, Ste-Marie PA, Schäfer M, Häuser W, Fitzcharles MA.
Schmerz. 2016 Feb;30(1):3-13. doi: 10.1007/s00482-015-0083-4.
PMID: 26767992 [PubMed – in process]
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11.Long-Term Data of Efficacy, Safety, and Tolerability in a Real-Life Setting of THC/CBD Oromucosal Spray-Treated Multiple Sclerosis Patients.
Paolicelli D, Direnzo V, Manni A, D’Onghia M, Tortorella C, Zoccolella S, Di Lecce V, Iaffaldano A, Trojano M.
J Clin Pharmacol. 2016 Jul;56(7):845-51. doi: 10.1002/jcph.670.
PMID: 26608223 [PubMed – in process]
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12.The disease-modifying effects of a Sativex-like combination of phytocannabinoids in mice with experimental autoimmune encephalomyelitis are preferentially due to ?9-tetrahydrocannabinol acting through CB1 receptors.
Moreno-Martet M, Feliú A, Espejo-Porras F, Mecha M, Carrillo-Salinas FJ, Fernández-Ruiz J, Guaza C, de Lago E.
Mult Scler Relat Disord. 2015 Nov;4(6):505-11. doi: 10.1016/j.msard.2015.08.001.
PMID: 26590655 [PubMed – indexed for MEDLINE]
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13.[There is evidence for the use of cannabinoids for symptomatic treatment of multiple sclerosis].
Bazinski H, Jensen HB, Stenager E.
Ugeskr Laeger. 2015 May 11;177(20):956-60. Review. Danish.
PMID: 26535431 [PubMed – indexed for MEDLINE]
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14.[Clinical pharmacology of medical cannabinoids in chronic pain].
Ing Lorenzini K, Broers B, Lalive PH, Dayer P, Desmeules J, Piguet V.
Rev Med Suisse. 2015 Jun 24;11(480):1390, 1392-4. Review. French.
PMID: 26267945 [PubMed – indexed for MEDLINE]
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15.Effect of Sativex on spasticity-associated symptoms in patients with multiple sclerosis.
Meuth SG, Vila C, Dechant KL.
Expert Rev Neurother. 2015;15(8):909-18. doi: 10.1586/14737175.2015.1067607. Review.
PMID: 26166264 [PubMed – indexed for MEDLINE]
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16.The effectiveness of cannabinoids in the management of chronic nonmalignant neuropathic pain: a systematic review.
Boychuk DG, Goddard G, Mauro G, Orellana MF.
J Oral Facial Pain Headache. 2015 Winter;29(1):7-14. doi: 10.11607/ofph.1274. Review.
PMID: 25635955 [PubMed – indexed for MEDLINE]
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17.Medical marijuana in neurology.
Benbadis SR, Sanchez-Ramos J, Bozorg A, Giarratano M, Kalidas K, Katzin L, Robertson D, Vu T, Smith A, Zesiewicz T.
Expert Rev Neurother. 2014 Dec;14(12):1453-65. doi: 10.1586/14737175.2014.985209. Review.
PMID: 25427150 [PubMed – indexed for MEDLINE]
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  1. As you probably know by now, the hangout labeled marijuana and pain is all about pcos.

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