Hashimoto’s Thyroiditis – Cutting Through the BS

In today’s cutting through the B.S. series on Hashimoto’s thyroiditis, we will be discussing why so many individuals with this condition continue to have complaints even though their lab numbers are well controlled with medication.  We will discuss how the paradigm needs to shift from Hashimoto’s being a thyroid problem to it being an immune system problem. Furthermore, we will go into the research regarding patients who have Hashimoto’s with normal thyroid levels, and how the autoimmune illness creates many of the same symptoms as one would experience with low thyroid hormones.

Dr. Martin Rutherford

Dr. Rutherford has worked with thousands of patients from all over the world to help them get to the root cause of their health issues and start to feel better again naturally.

If you are interested in having a consultation with Dr. Rutherford to discuss your specific case and if he feels you would be a good candidate for his protocols please visit http://powerhealthconsult.com.


1.Imbalances in T Cell-Related Transcription Factors Among Patients with Hashimoto’s Thyroiditis.
 Safdari V, Alijani E, Nemati M, Jafarzadeh A.
 Sultan Qaboos Univ Med J. 2017 May;17(2):e174-e180. doi: 10.18295/squmj.2016.17.02.007. Epub 2017 Jun 20.
 PMID: 28690889 [PubMed – in process] Free PMC Article
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2.Human limbal fibroblast-like stem cells induce immune-tolerance in autoreactive T lymphocytes from female patients with Hashimoto’s thyroiditis.
 Coppola A, Tomasello L, Pitrone M, Cillino S, Richiusa P, Pizzolanti G, Giordano C.
 Stem Cell Res Ther. 2017 Jul 3;8(1):154. doi: 10.1186/s13287-017-0611-5.
 PMID: 28673339 [PubMed – in process] Free PMC Article
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3.Increased Levels of Serum Interleukin-17 in Patients with Hashimoto’s Thyroiditis.
 Esfahanian F, Ghelich R, Rashidian H, Jadali Z.
 Indian J Endocrinol Metab. 2017 Jul-Aug;21(4):551-554. doi: 10.4103/ijem.IJEM_412_16.
 PMID: 28670539 [PubMed] Free PMC Article
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4.The Serological and Biochemical Markers of Adrenal Cortex and Endocrine Pancreas Dysfunction in Patients with Hashimoto’s Thyroiditis: A Hospital-based Pilot Study.
 Sahoo JP, Selviambigapathy J, Kamalanathan S, Negi VS, Sridhar MG, Kar SS, Vivekanandan M.
 Indian J Endocrinol Metab. 2017 Jul-Aug;21(4):540-544. doi: 10.4103/ijem.IJEM_72_17.
 PMID: 28670537 [PubMed] Free PMC Article
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5.Pathogenic Th17 and Th22 cells are increased in patients with autoimmune thyroid disorders.
 Vitales-Noyola M, Ramos-Levi AM, Martínez-Hernández R, Serrano-Somavilla A, Sampedro-Nuñez M, González-Amaro R, Marazuela M.
 Endocrine. 2017 Jul 1. doi: 10.1007/s12020-017-1361-y. [Epub ahead of print]
 PMID: 28669056 [PubMed – as supplied by publisher]
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6.Altered expression of CTLA-4, CD28, VDR, and CD45 mRNA in T cells of patients with Hashimoto’s thyroiditis – a pilot study.
 Toki? S, Štefani? M, Karner I, Glavaš-Obrovac L.
 Endokrynol Pol. 2017;68(3):274-828. doi: 10.5603/EP.2017.0020.
 PMID: 28660994 [PubMed – in process] Free Article
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7.Increased risk of thyroid diseases in patients with systemic lupus erythematosus: A nationwide population-based Study in Korea.
 Yun JS, Bae JM, Kim KJ, Jung YS, Kim GM, Kim HR, Lee JS, Ko SH, Cha SA, Ahn YB.
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8.Role of the tumour necrosis factor-like weak inducer of apoptosis (TWEAK)/fibroblast growth factor-inducible 14 (Fn14) axis in autoimmune thyroid disease.
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9.Autoimmune Thyroiditis and Glomerulopathies.
 Santoro D, Vadalà C, Siligato R, Buemi M, Benvenga S.
 Front Endocrinol (Lausanne). 2017 Jun 2;8:119. doi: 10.3389/fendo.2017.00119. eCollection 2017. Review.
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10.A concise review of Hashimoto thyroiditis (HT) and the importance of iodine, selenium, vitamin D and gluten on the autoimmunity and dietary management of HT patients.Points that need more investigation.
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11.High Proportions of People With Nonceliac Wheat Sensitivity Have Autoimmune Disease or Antinuclear Antibodies.
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12.The role of Epstein-Barr virus infection in the development of autoimmune thyroid diseases.
 Janegova A, Janega P, Rychly B, Kuracinova K, Babal P.
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13.CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis.
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14.Hashimoto’s thyroiditis affects symptom load and quality of life unrelated to hypothyroidism: a prospective case-control study in women undergoing thyroidectomy for benign goiter.
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15.Cognitive and affective dysfunctions in autoimmune thyroiditis.
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16.Increased occurrence of weaknesses in attention testing in patients with Hashimoto’s thyroiditis compared to patients with other thyroid illnesses.
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17.What is brain fog? An evaluation of the symptom in postural tachycardia syndrome.
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18.Brain “fog,” inflammation and obesity: key aspects of neuropsychiatric disorders improved by luteolin.
 Theoharides TC, Stewart JM, Hatziagelaki E, Kolaitis G.
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19.Caught in the thickness of brain fog: exploring the cognitive symptoms of Chronic Fatigue Syndrome.
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20.Cognitive impairment in coeliac disease improves on a gluten-free diet and correlates with histological and serological indices of disease severity.
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21.Fibrofog and fibromyalgia: a narrative review and implications for clinical practice.
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23.Exercise, fibromyalgia, and fibrofog: a pilot study.
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24.[Cognitive impairment in patients suffering from fibromyalgia. An underestimated problem].
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25.A Comparison of Fibromyalgia Symptoms in Patients with Healthy versus Depressive, Low and Reactive Affect Balance Styles.
 Toussaint LL, Vincent A, McAllister SJ, Oh TH, Hassett AL.
 Scand J Pain. 2014 Mar 1;5(3):161-166.
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26.Gluten-induced cognitive impairment (“brain fog”) in coeliac disease.
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 J Gastroenterol Hepatol. 2017 Mar;32 Suppl 1:90-93. doi: 10.1111/jgh.13706. Review.
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27.Is thyroid autoimmunity itself associated with psychological well-being in euthyroid Hashimoto’s thyroiditis?
 Yalcin MM, Altinova AE, Cavnar B, Bolayir B, Akturk M, Arslan E, Ozkan C, Cakir N, Balos Toruner F.
 Endocr J. 2017 Apr 29;64(4):425-429. doi: 10.1507/endocrj.EJ16-0418. Epub 2017 Mar 4.
 PMID: 28260699 [PubMed – in process] Free Article
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28.A pattern of cerebral perfusion anomalies between major depressive disorder and Hashimoto thyroiditis.
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 BMC Psychiatry. 2011 Sep 13;11:148. doi: 10.1186/1471-244X-11-148.
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29.Increased prevalence of sublinical brain perfusion abnormalities in patients with autoimmune thyroiditis: evidence of Hashimoto’s encephalitis?
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30.Nodular thyroid disease and thyroid malignancy: Experience at Polokwane Mankweng Hospital Complex, Limpopo Province, South Africa.
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31.Lower Serum 25-Hydroxyvitamin D Level is Associated With 3 Types of Autoimmune Thyroid Diseases.
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32.Sexual function and depressive symptoms in young women with thyroid autoimmunity and subclinical hypothyroidism.
 Krysiak R, Drosdzol-Cop A, Skrzypulec-Plinta V, Okopien B.
 Clin Endocrinol (Oxf). 2016 Jun;84(6):925-31. doi: 10.1111/cen.12956. Epub 2015 Oct 19.
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33.In children with Hashimoto’s thyroiditis the evolution over time of thyroid status may differ according to the different presentation patterns.
 Zirilli G, Velletri MR, Porcaro F, Candela G, Maisano P, La Monica G.
 Acta Biomed. 2015 Sep 14;86(2):137-41. Review.
 PMID: 26422427 [PubMed – indexed for MEDLINE]
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34.Simultaneous measurement of serum chemokines in autoimmune thyroid diseases: possible role of IP-10 in the inflammatory response.
 Hiratsuka I, Itoh M, Yamada H, Yamamoto K, Tomatsu E, Makino M, Hashimoto S, Suzuki A.
 Endocr J. 2015;62(12):1059-66. doi: 10.1507/endocrj.EJ15-0448. Epub 2015 Sep 20.
 PMID: 26400025 [PubMed – indexed for MEDLINE] Free Article
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35.Do antithyroid antibodies affect hearing outcomes in patients with pediatric euthyroid Hashimoto’s thyroiditis?
 Renda L, Parlak M, Selçuk ÖT, Renda R, Eyigör H, Y?lmaz MD, Osma Ü, Filiz S.
 Int J Pediatr Otorhinolaryngol. 2015 Dec;79(12):2043-9. doi: 10.1016/j.ijporl.2015.09.006. Epub 2015 Sep 10.
 PMID: 26388187 [PubMed – indexed for MEDLINE]
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36.Five-year prospective evaluation of thyroid function in girls with subclinical mild hypothyroidism of different etiology.
 Wasniewska M, Aversa T, Salerno M, Corrias A, Messina MF, Mussa A, Capalbo D, De Luca F, Valenzise M.
 Eur J Endocrinol. 2015 Dec;173(6):801-8. doi: 10.1530/EJE-15-0484. Epub 2015 Sep 15.
 PMID: 26374873 [PubMed – indexed for MEDLINE] Free Article
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37.Different Effects of Metformin on the Hypothalamic-Pituitary-Thyroid Axis in Bromocriptine- and Cabergoline-treated Patients with Hashimoto’s Thyroiditis and Glucose Metabolism Abnormalities.
 Krysiak R, Okrzesik J, Okopien B.
 Exp Clin Endocrinol Diabetes. 2015 Oct;123(9):561-6. doi: 10.1055/s-0035-1564073. Epub 2015 Sep 15.
 PMID: 26372847 [PubMed – indexed for MEDLINE]
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38.The Role of Iodine and Selenium in Autoimmune Thyroiditis.
 Duntas LH.
 Horm Metab Res. 2015 Sep;47(10):721-6. doi: 10.1055/s-0035-1559631. Epub 2015 Sep 11. Review.
 PMID: 26361258 [PubMed – indexed for MEDLINE]
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39.The Pathogenesis of Hashimoto’s Thyroiditis: Further Developments in our Understanding.
 Ajjan RA, Weetman AP.
 Horm Metab Res. 2015 Sep;47(10):702-10. doi: 10.1055/s-0035-1548832. Epub 2015 Apr 16. Review.
 PMID: 26361257 [PubMed – indexed for MEDLINE]
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40.The relationship between oxidative stress and autoimmunity in Hashimoto’s thyroiditis.
 Ates I, Yilmaz FM, Altay M, Yilmaz N, Berker D, Güler S.
 Eur J Endocrinol. 2015 Dec;173(6):791-9. doi: 10.1530/EJE-15-0617. Epub 2015 Sep 4.
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41.HLA Class II Differentiates Between Thyroid and Polyglandular Autoimmunity.
 Barkia Beradhi S, Flesch BK, Hansen MP, Matheis N, Kahaly GJ.
 Horm Metab Res. 2016 Apr;48(4):232-7. doi: 10.1055/s-0035-1559622. Epub 2015 Aug 28.
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42.Vitamin D Deficiency and Hashimoto’s Thyroiditis in Children and Adolescents: a Critical Vitamin D Level for This Association?
 Evliyao?lu O, Acar M, Özcab? B, Erginöz E, Bucak F, Ercan O, Kucur M.
 J Clin Res Pediatr Endocrinol. 2015 Jun;7(2):128-33. doi: 10.4274/jcrpe.2011.
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43.Selenium and the thyroid.
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 Curr Opin Endocrinol Diabetes Obes. 2015 Oct;22(5):392-401. doi: 10.1097/MED.0000000000000190. Review.
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44.The presentation of lymph nodes in Hashimoto’s thyroiditis on ultrasound.
 Jones MR, Mohamed H, Catlin J, April D, Al-Qurayshi Z, Kandil E.
 Gland Surg. 2015 Aug;4(4):301-6. doi: 10.3978/j.issn.2227-684X.2015.05.11. Erratum in: Gland Surg. 2015 Dec;4(6):E2.
 PMID: 26311120 [PubMed] Free PMC Article
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45.IL-4, IL-10 and high sensitivity-CRP as potential serum biomarkers of persistent/recurrent disease in papillary thyroid carcinoma with/without Hashimoto’s thyroiditis.
 Stanciu AE, Serdarevic N, Hurduc AE, Stanciu MM.
 Scand J Clin Lab Invest. 2015 Nov;75(7):539-48. doi: 10.3109/00365513.2015.1057895. Epub 2015 Jul 25.
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46.Celiac disease and Hashimoto’s thyroiditis: a shared plot?
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 Int J Colorectal Dis. 2016 Apr;31(4):947. doi: 10.1007/s00384-015-2370-z. Epub 2015 Aug 23. No abstract available.
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47.Autoimmunity and thyrotropin level in developing thyroid malignancy.
 Medenica S, Radojevic N, Stojkovic M, Nedeljkovic-Beleslin B, Savic S, Ciric J, Trbojevic B, Zarkovic M.
 Eur Rev Med Pharmacol Sci. 2015 Aug;19(15):2824-9.
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48.The role of diffusion weighted MR imaging for differentiation between Graves’ disease and Hashimoto thyroiditis.
 Ozturk T, Bozgeyik Z, Ozturk F, Burakgazi G, Akyol M, Coskun S, Ozkan Y, Ogur E.
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49.Many confounding factors can affect mean platelet volume in euthyroid Hashimoto’s thyroiditis patients.
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 Blood Coagul Fibrinolysis. 2015 Sep;26(6):714-5. doi: 10.1097/MBC.0000000000000299. No abstract available.
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50.Immunogenetics of autoimmune thyroid diseases: A comprehensive review.
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 J Autoimmun. 2015 Nov;64:82-90. doi: 10.1016/j.jaut.2015.07.009. Epub 2015 Jul 30. Review.
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51.Eradication of Blastocystis hominis prevents the development of symptomatic Hashimoto’s thyroiditis: a case report.
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52.Thyroid dysfunction: an autoimmune aspect.
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 Int J Clin Exp Med. 2015 May 15;8(5):6677-81. eCollection 2015. Review.
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53.B Cell Activating Factor (BAFF) and BAFF Receptor Expression in Autoimmune and Nonautoimmune Thyroid Diseases.
 Campi I, Tosi D, Rossi S, Vannucchi G, Covelli D, Colombo F, Trombetta E, Porretti L, Vicentini L, Cantoni G, Currò N, Beck-Peccoz P, Bulfamante G, Salvi M.
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54.Circulating levels of irisin is elevated in hypothyroidism, a case-control study.
 Ate? ?, Altay M, Topçuo?lu C, Y?lmaz FM.
 Arch Endocrinol Metab. 2016 Apr;60(2):95-100. doi: 10.1590/2359-3997000000077. Epub 2015 Jul 21.
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55.Infection and persistence of erythrovirus B19 in benign and cancerous thyroid tissues.
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56.Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study.
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57.Maternal Thyroid Disease and Preterm Birth: Systematic Review and Meta-Analysis.
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58.Association between previously unknown connective tissue disease and subclinical hypothyroidism diagnosed during first trimester of pregnancy.
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59.Marginal Iodine Status and High Rate of Subclinical Hypothyroidism in Washington DC Women Planning Conception.
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60.[Characteristics of postpartum thyroid dysfunction].
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61.Should all women be screened for thyroid dysfunction in pregnancy?
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62.Effect of gestational subclinical hypothyroidism on early neurodevelopment of offspring.
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63.The effect of maternal subclinical hypothyroidism on IQ in 7- to 8-year-old children: A case-control review.
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64.Thyroid dysfunction and thyroid autoimmunity in euthyroid women in achieving fertility.
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65.The effect of hypothyroidism occurring in patients with metabolic syndrome.
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66.On the Severity of Carpal Tunnel Syndrome: Diabetes or Metabolic Syndrome.
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67.[Alterations of the thyroid function in patients with morbid obesity].
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  1. Angelique Tittmann

    This was a really informative video. You mentioned early in the video that you would discuss the rare times when Hashimoto’s causes weight loss instead of weight gain. I don’t think you ever mentioned it, though. Is there another video where you discuss that?

  2. Glad you found it informative. Sorry if we did not touch on that subject. Here is a video we did specifically on that http://powerhealthtalk.com/the-thin-hashimotos-patient.htm

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