Alzheimer’s and Sleep

Today we will be discussing the bidirectional relationship between Alzheimer’s and sleep. We hope that you find this broadcast helpful and please send us any of your questions.

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1.Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease.
Egan MF, Kost J, Tariot PN, Aisen PS, Cummings JL, Vellas B, Sur C, Mukai Y, Voss T, Furtek C, Mahoney E, Harper Mozley L, Vandenberghe R, Mo Y, Michelson D.
N Engl J Med. 2018 May 3;378(18):1691-1703. doi: 10.1056/NEJMoa1706441.
PMID: 29719179 [PubMed – in process]
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2.REM Sleep Behavior Disorder and Alzheimer’s Disease: Definitely No Relationship?
Galbiati A, Carli G, Hensley M, Ferini-Strambi L.
J Alzheimers Dis. 2018;63(1):1-11. doi: 10.3233/JAD-171164.
PMID: 29578489 [PubMed – in process]
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3.Physiological changes in neurodegeneration – mechanistic insights and clinical utility.
Ahmed RM, Ke YD, Vucic S, Ittner LM, Seeley W, Hodges JR, Piguet O, Halliday G, Kiernan MC.
Nat Rev Neurol. 2018 May;14(5):259-271. doi: 10.1038/nrneurol.2018.23. Epub 2018 Mar 23. Review.
PMID: 29569624 [PubMed – in process]
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4.Microglia-Mediated Synapse Loss in Alzheimer’s Disease.
Rajendran L, Paolicelli RC.
J Neurosci. 2018 Mar 21;38(12):2911-2919. doi: 10.1523/JNEUROSCI.1136-17.2017.
PMID: 29563239 [PubMed – in process]
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