Hypothyroidism, the Truths Regarding Alternative and Mainstream Treatments

Patients with hypothyroidism frequently express to us that they have tremendous confusion regarding claims on the internet regarding the success of alternative treatments, whether to take iodine, if it is safe for them to eat broccoli, and whether they should try an animal glandular or not.   In today’s broadcast we will discuss the up to date information regarding mainstream medical and alternative approaches for thyroid management.
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References:
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Bhuiyan MM, Machowski A.
S Afr Med J. 2015 Sep 22;105(7):570-2. doi: 10.7196/SAMJnew.7885.
PMID: 26428754 [PubMed – in process]
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2. Lower Serum 25-Hydroxyvitamin D Level is Associated With 3 Types of Autoimmune Thyroid Diseases.
Ma J, Wu D, Li C, Fan C, Chao N, Liu J, Li Y, Wang R, Miao W, Guan H, Shan Z, Teng W.
Medicine (Baltimore). 2015 Sep;94(39):e1639. doi: 10.1097/MD.0000000000001639.
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3. Sexual function and depressive symptoms in young women with thyroid autoimmunity and subclinical hypothyroidism.
Krysiak R, Drosdzol-Cop A, Skrzypulec-Plinta V, Okopien B.
Clin Endocrinol (Oxf). 2015 Oct 1. doi: 10.1111/cen.12956. [Epub ahead of print]
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4. In children with Hashimoto’s thyroiditis the evolution over time of thyroid status may differ according to the different presentation patterns.
Zirilli G, Velletri MR, Porcaro F, Candela G, Maisano P, La Monica G.
Acta Biomed. 2015 Sep 14;86(2):137-41.
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5. Simultaneous measurement of serum chemokines in autoimmune thyroid diseases: possible role of IP-10 in the inflammatory response.
Hiratsuka I, Itoh M, Yamada H, Yamamoto K, Tomatsu E, Makino M, Hashimoto S, Suzuki A.
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6. Do antithyroid antibodies affect hearing outcomes in patients with pediatric euthyroid Hashimoto’s thyroiditis?
Renda L, Parlak M, Selçuk ÖT, Renda R, Eyigör H, Y?lmaz MD, Osma Ü, Filiz S.
Int J Pediatr Otorhinolaryngol. 2015 Sep 10. pii: S0165-5876(15)00452-8. doi: 10.1016/j.ijporl.2015.09.006. [Epub ahead of print]
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7. Five-year prospective evaluation of thyroid function in girls with subclinical mild hypothyroidism of different etiology.
Wasniewska M, Aversa T, Salerno M, Corrias A, Messina MF, Mussa A, Capalbo D, De Luca F, Valenzise M.
Eur J Endocrinol. 2015 Sep 15. pii: EJE-15-0484. [Epub ahead of print]
PMID: 26374873 [PubMed – as supplied by publisher]
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8. Different Effects of Metformin on the Hypothalamic-Pituitary-Thyroid Axis in Bromocriptine- and Cabergoline-treated Patients with Hashimoto’s Thyroiditis and Glucose Metabolism Abnormalities.
Krysiak R, Okrzesik J, Okopien B.
Exp Clin Endocrinol Diabetes. 2015 Sep 15. [Epub ahead of print]
PMID: 26372847 [PubMed – as supplied by publisher]
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9. The Role of Iodine and Selenium in Autoimmune Thyroiditis.
Duntas LH.
Horm Metab Res. 2015 Sep;47(10):721-6. doi: 10.1055/s-0035-1559631. Epub 2015 Sep 11.
PMID: 26361258 [PubMed – in process]
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10. The Pathogenesis of Hashimoto’s Thyroiditis: Further Developments in our Understanding.
Ajjan RA, Weetman AP.
Horm Metab Res. 2015 Sep;47(10):702-10. doi: 10.1055/s-0035-1548832. Epub 2015 Apr 16.
PMID: 26361257 [PubMed – in process]
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11. The Relationship between Oxidative Stress and Autoimmunity in Hashimoto’s Thyroiditis.
Ate? ?, Yilmaz FM, Altay M, Yilmaz N, Berker D, Güler S.
Eur J Endocrinol. 2015 Sep 4. pii: EJE-15-0617. [Epub ahead of print]
PMID: 26340971 [PubMed – as supplied by publisher]
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12. HLA Class II Differentiates Between Thyroid and Polyglandular Autoimmunity.
Barkia Beradhi S, Flesch BK, Hansen MP, Matheis N, Kahaly GJ.
Horm Metab Res. 2015 Aug 28. [Epub ahead of print]
PMID: 26317691 [PubMed – as supplied by publisher]
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13. Vitamin D Deficiency and Hashimoto’s Thyroiditis in Children and Adolescents: a Critical Vitamin D Level for This Association?
Evliyao?lu O, Acar M, Özcab? B, Erginöz E, Bucak F, Ercan O, Kucur M.
J Clin Res Pediatr Endocrinol. 2015 Jun 5;7(2):128-33. doi: 10.4274/jcrpe.2011.
PMID: 26316435 [PubMed – in process]
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14. Selenium and the thyroid.
Köhrle J.
Curr Opin Endocrinol Diabetes Obes. 2015 Oct;22(5):392-401. doi: 10.1097/MED.0000000000000190.
PMID: 26313901 [PubMed – in process]
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15. The presentation of lymph nodes in Hashimoto’s thyroiditis on ultrasound.
Jones MR, Mohamed H, Catlin J, April D, Al-Qurayshi Z, Kandil E.
Gland Surg. 2015 Aug;4(4):301-6. doi: 10.3978/j.issn.2227-684X.2015.05.11.
PMID: 26311120 [PubMed] Free PMC Article
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16. IL-4, IL-10 and high sensitivity-CRP as potential serum biomarkers of persistent/recurrent disease in papillary thyroid carcinoma with/without Hashimoto’s thyroiditis.
Stanciu AE, Serdarevic N, Hurduc AE, Stanciu MM.
Scand J Clin Lab Invest. 2015 Nov;75(7):539-48. doi: 10.3109/00365513.2015.1057895. Epub 2015 Jul 25.
PMID: 26305420 [PubMed – in process]
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17. Celiac disease and Hashimoto’s thyroiditis: a shared plot?
Mormile R.
Int J Colorectal Dis. 2015 Aug 23. [Epub ahead of print] No abstract available.
PMID: 26298181 [PubMed – as supplied by publisher]
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18. Autoimmunity and thyrotropin level in developing thyroid malignancy.
Medenica S, Radojevic N, Stojkovic M, Nedeljkovic-Beleslin B, Savic S, Ciric J, Trbojevic B, Zarkovic M.
Eur Rev Med Pharmacol Sci. 2015 Aug;19(15):2824-9.
PMID: 26241536 [PubMed – in process] Free Article
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19. The role of diffusion weighted MR imaging for differentiation between Graves’ disease and Hashimoto thyroiditis.
Ozturk T, Bozgeyik Z, Ozturk F, Burakgazi G, Akyol M, Coskun S, Ozkan Y, Ogur E.
Eur Rev Med Pharmacol Sci. 2015 Aug;19(15):2798-803.
PMID: 26241532 [PubMed – in process]
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20. Many confounding factors can affect mean platelet volume in euthyroid Hashimoto’s thyroiditis patients.
Varol E.
Blood Coagul Fibrinolysis. 2015 Sep;26(6):714-5. doi: 10.1097/MBC.0000000000000299. No abstract available.
PMID: 26236946 [PubMed – in process]
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21. Immunogenetics of autoimmune thyroid diseases: A comprehensive review.
Lee HJ, Li CW, Hammerstad SS, Stefan M, Tomer Y.
J Autoimmun. 2015 Jul 30. pii: S0896-8411(15)30012-3. doi: 10.1016/j.jaut.2015.07.009. [Epub ahead of print] Review.
PMID: 26235382 [PubMed – as supplied by publisher]
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22. Eradication of Blastocystis hominis prevents the development of symptomatic Hashimoto’s thyroiditis: a case report.
Raji? B, Arapovi? J, Raguž K, Boškovi? M, Babi? SM, Masla? S.
J Infect Dev Ctries. 2015 Jul 30;9(7):788-91. doi: 10.3855/jidc.4851.
PMID: 26230132 [PubMed – in process] Free Article
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23. Thyroid dysfunction: an autoimmune aspect.
Khan FA, Al-Jameil N, Khan MF, Al-Rashid M, Tabassum H.
Int J Clin Exp Med. 2015 May 15;8(5):6677-81. eCollection 2015. Review.
PMID: 26221205 [PubMed] Free PMC Article
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24. B Cell Activating Factor (BAFF) and BAFF Receptor Expression in Autoimmune and Nonautoimmune Thyroid Diseases.
Campi I, Tosi D, Rossi S, Vannucchi G, Covelli D, Colombo F, Trombetta E, Porretti L, Vicentini L, Cantoni G, Currò N, Beck-Peccoz P, Bulfamante G, Salvi M.
Thyroid. 2015 Sep;25(9):1043-9. doi: 10.1089/thy.2015.0029. Epub 2015 Aug 13.
PMID: 26214745 [PubMed – in process]
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25. Circulating levels of irisin is elevated in hypothyroidism, a case-control study.
Ate? ?, Altay M, Topçuo?lu C, Y?lmaz FM.
Arch Endocrinol Metab. 2015 Jul 21:0. [Epub ahead of print]
PMID: 26201007 [PubMed – as supplied by publisher] Free Article
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26. The role of Epstein-Barr virus infection in the development of autoimmune thyroid diseases.
Janegova A, Janega P, Rychly B, Kuracinova K, Babal P.
Endokrynol Pol. 2015;66(2):132-6. doi: 10.5603/EP.2015.0020.
PMID: 25931043 [PubMed – in process] Free Article
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27. Infection and persistence of erythrovirus B19 in benign and cancerous thyroid tissues.
Adamson LA, Fowler LJ, Ewald AS, Clare-Salzler MJ, Hobbs JA.
J Med Virol. 2014 Sep;86(9):1614-20. doi: 10.1002/jmv.23852. Epub 2013 Nov 21.
PMID: 24265024 [PubMed – indexed for MEDLINE]
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28. Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study.
Feldthusen AD, Pedersen PL, Larsen J, Toft Kristensen T, Ellervik C, Kvetny J.
J Pregnancy. 2015;2015:132718. doi: 10.1155/2015/132718. Epub 2015 Aug 17.
PMID: 26351582 [PubMed – in process] Free PMC Article
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29. Maternal thyroid disease and preterm birth: systematic review and meta-analysis.
Sheehan PM, Nankervis A, Araujo Júnior E, Da Silva Costa F.
J Clin Endocrinol Metab. 2015 Sep 18:jc20153074. [Epub ahead of print]
PMID: 26383905 [PubMed – as supplied by publisher]
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30. Association between previously unknown connective tissue disease and subclinical hypothyroidism diagnosed during first trimester of pregnancy.
Beneventi F, Locatelli E, Alpini C, Lovati E, Ramoni V, Simonetta M, Cavagnoli C, Spinillo A.
Fertil Steril. 2015 Aug 19. pii: S0015-0282(15)01670-2. doi: 10.1016/j.fertnstert.2015.07.1158. [Epub ahead of print]
PMID: 26297901 [PubMed – as supplied by publisher]
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31. Marginal Iodine Status and High Rate of Subclinical Hypothyroidism in Washington DC Women Planning Conception.
Stagnaro-Green A, Dogo-Isonaige E, Pearce EN, Spencer C, Gaba ND.
Thyroid. 2015 Oct;25(10):1151-4. doi: 10.1089/thy.2015.0063. Epub 2015 Aug 7.
PMID: 26160595 [PubMed – in process]
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32. [Characteristics of postpartum thyroid dysfunction].
Argatska A, Nonchev B, Obretsova M, Pehlivanov B.
Akush Ginekol (Sofiia). 2015;54(3):3-8. Bulgarian.
PMID: 26137772 [PubMed – indexed for MEDLINE]
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33. Should all women be screened for thyroid dysfunction in pregnancy?
Taylor PN, Okosieme OE, Premawardhana L, Lazarus JH.
Womens Health (Lond Engl). 2015 Jun;11(3):295-307. doi: 10.2217/whe.15.7.
PMID: 26102469 [PubMed – in process]
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34. Effect of gestational subclinical hypothyroidism on early neurodevelopment of offspring.
Chen LM, Chen QS, Jin GX, Si GX, Zhang Q, Ye EL, Yang H, Cai LQ, Peng MM, Lin ZZ, Yu LC, Zhang C, Lu XM.
J Perinatol. 2015 Sep;35(9):678-82. doi: 10.1038/jp.2015.66. Epub 2015 Jun 18.
PMID: 26087317 [PubMed – in process]
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35. The effect of maternal subclinical hypothyroidism on IQ in 7- to 8-year-old children: A case-control review.
Murphy NC, Diviney MM, Donnelly JC, Cooley SM, Kirkham CH, Foran AM, Breathnach FM, Malone FD, Geary MP.
Aust N Z J Obstet Gynaecol. 2015 Oct;55(5):459-63. doi: 10.1111/ajo.12338. Epub 2015 Jun 8.
PMID: 26058422 [PubMed – in process]
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36. Thyroid dysfunction and thyroid autoimmunity in euthyroid women in achieving fertility.
Medenica S, Nedeljkovic O, Radojevic N, Stojkovic M, Trbojevic B, Pajovic B.
Eur Rev Med Pharmacol Sci. 2015;19(6):977-87.
PMID: 25855922 [PubMed – in process] Free Article
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37. The effect of hypothyroidism occurring in patients with metabolic syndrome.
Gierach M, Junik R.
Endokrynol Pol. 2015;66(4):288-94. doi: 10.5603/EP.2015.0036.
PMID: 26323464 [PubMed – in process] Free Article
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38. On the Severity of Carpal Tunnel Syndrome: Diabetes or Metabolic Syndrome.
Gül Yurdakul F, Bodur H, Öztop Çakmak Ö, Ate? C, Sivas F, Eser F, Y?lmaz Ta?delen Ö.
J Clin Neurol. 2015 Jul;11(3):234-40. doi: 10.3988/jcn.2015.11.3.234.
PMID: 26174786 [PubMed] Free PMC Article
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39. [Alterations of the thyroid function in patients with morbid obesity].
Montoya-Morales DS, Tapia-González Mde L, Alamilla-Lugo L, Sosa-Caballero A, Muñoz-Solís A, Jiménez-Sánchez M.
Rev Med Inst Mex Seguro Soc. 2015;53 Suppl 1:S18-22. Spanish.
PMID: 26020658 [PubMed – in process]
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40. Hypothyroidism and depression: salient aspects of pathogenesis and management.
Duntas LH, Maillis A.
Minerva Endocrinol. 2013 Dec;38(4):365-77. Review.
PMID: 24285104 [PubMed – indexed for MEDLINE]
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One Comment

  1. wonderful, thanks

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