Today we will be discussing triggers for Hashimoto’s thyroiditis and Hypothyroidism and the current research on stress as well as trauma as it pertains to these issues. We will also go into our clinical experience on these matters.
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References:
1. | Favorable effects of myo-inositol, selenomethionine or their combination on the hydrogen peroxide-induced oxidative stress of peripheral mononuclear cells from patients with Hashimoto’s thyroiditis: preliminary in vitro studies. |
Benvenga S, Vicchio T, Di Bari F, Vita R, Fallahi P, Ferrari SM, Catania S, Costa C, Antonelli A. | |
Eur Rev Med Pharmacol Sci. 2017 Jun;21(2 Suppl):89-101. | |
PMID: 28724172 [PubMed – in process] | |
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2. | Proteins oxidation and autoantibodies’ reactivity against hydrogen peroxide and malondialdehyde -oxidized thyroid antigens in patients’ plasmas with Graves’ disease and Hashimoto Thyroiditis. |
Mseddi M, Ben Mansour R, Gargouri B, Mnif F, El Ghawi S, Hammami B, Ghorbel A, Abid M, Lassoued S. | |
Chem Biol Interact. 2017 Jun 25;272:145-152. doi: 10.1016/j.cbi.2017.04.013. Epub 2017 Apr 18. | |
PMID: 28431875 [PubMed – indexed for MEDLINE] | |
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3. | Selenium supplementation modulates apoptotic processes in thyroid follicular cells. |
Nettore IC, De Nisco E, Desiderio S, Passaro C, Maione L, Negri M, Albano L, Pivonello R, Pivonello C, Portella G, Ungaro P, Colao A, Macchia PE. | |
Biofactors. 2017 May 6;43(3):415-423. doi: 10.1002/biof.1351. Epub 2017 Mar 2. | |
PMID: 28251705 [PubMed – in process] | |
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4. | RAGE polymorphisms and oxidative stress levels in Hashimoto’s thyroiditis. |
Giannakou M, Saltiki K, Mantzou E, Loukari E, Philippou G, Terzidis K, Lili K, Stavrianos C, Kyprianou M, Alevizaki M. | |
Eur J Clin Invest. 2017 May;47(5):341-347. doi: 10.1111/eci.12739. Epub 2017 Mar 20. | |
PMID: 28226412 [PubMed – in process] | |
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5. | A comparative study of nuclear 8-hydroxyguanosine expression in Autoimmune Thyroid Diseases and Papillary Thyroid Carcinoma and its relationship with p53, Bcl-2 and Ki-67 cancer related proteins. |
Mseddi M, Ben Mansour R, Gouiia N, Mnif F, Bousselaa R, Abid M, Boudaouara T, Attia H, Lassoued S. | |
Adv Med Sci. 2017 Mar;62(1):45-51. doi: 10.1016/j.advms.2016.06.003. Epub 2016 Jun 22. | |
PMID: 28187375 [PubMed – in process] | |
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6. | No definitive evidence for a connection between autoimmune thyroid diseases and stress in women. |
Damian L, Ghiciuc CM, Dima-Cozma LC, Ungureanu MC, Cozma S, Patacchioli FR, Lupusoru CE. | |
Neuro Endocrinol Lett. 2016 Jul;37(3):155-162. Review. | |
PMID: 27618605 [PubMed – indexed for MEDLINE] | |
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7. | Serum anti-Müllerian hormone levels in euthyroid adolescent girls with Hashimoto’s thyroiditis: relationship to antioxidant status. |
Erol O, Parlak M, Ellida? HY, Parlak AE, Derbent AU, Eren E, Y?lmaz N. | |
Eur J Obstet Gynecol Reprod Biol. 2016 Aug;203:204-9. doi: 10.1016/j.ejogrb.2016.06.002. Epub 2016 Jun 14. | |
PMID: 27343736 [PubMed – indexed for MEDLINE] | |
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8. | Clinical Relevance of Environmental Factors in the Pathogenesis of Autoimmune Thyroid Disease. |
Wiersinga WM. | |
Endocrinol Metab (Seoul). 2016 Jun;31(2):213-22. doi: 10.3803/EnM.2016.31.2.213. Epub 2016 May 13. Review. | |
PMID: 27184015 [PubMed] Free PMC Article | |
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9. | T-wave inversions on ECG as primary manifestation of Hashimoto’s disease. |
Araque KA, Smith MJ, Walsh BM. | |
BMJ Case Rep. 2016 Apr 7;2016. pii: bcr2016214949. doi: 10.1136/bcr-2016-214949. | |
PMID: 27056941 [PubMed – indexed for MEDLINE] | |
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10. | Dynamic thiol/disulfide homeostasis in patients with autoimmune subclinical hypothyroidism. |
Ates I, Altay M, Yilmaz FM, Topcuoglu C, Neselioglu S, Erel O, Yilmaz N. | |
Endocr Res. 2016 Nov;41(4):343-349. Epub 2016 Apr 4. | |
PMID: 27045442 [PubMed – indexed for MEDLINE] | |
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11. | The impact of levothyroxine sodium treatment on oxidative stress in Hashimoto’s thyroiditis. |
Ates I, Altay M, Yilmaz FM, Topcuoglu C, Yilmaz N, Berker D, Guler S. | |
Eur J Endocrinol. 2016 Jun;174(6):727-34. doi: 10.1530/EJE-15-1061. Epub 2016 Mar 7. | |
PMID: 26951600 [PubMed – indexed for MEDLINE] Free Article | |
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12. | Immune System Effects on the Endocrine System. |
Boutzios G, Kaltsas G. In: De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A, editors. | |
Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. | |
PMID: 25905362 [PubMed] Free Books & Documents | |
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13. | Celiac disease in children and adolescents with Hashimoto Thyroiditis. |
Tuhan H, I??k S, Abac? A, ?im?ek E, An?k A, Anal Ö, Böber E. | |
Turk Pediatri Ars. 2016 Jun 1;51(2):100-5. doi: 10.5152/TurkPediatriArs.2016.3 | |
PMID: 27489467 [PubMed] Free PMC Article | |
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14. | An Adolescent Boy with Comorbid Anorexia Nervosa and Hashimoto Thyroiditis. |
Pehlivantürk K?z?lkan M, Kanbur N, Akgül S, Alika?ifo?lu A. | |
J Clin Res Pediatr Endocrinol. 2016 Mar 5;8(1):92-5. doi: 10.4274/jcrpe.2297. Epub 2015 Dec 18. | |
PMID: 26757948 [PubMed – indexed for MEDLINE] Free PMC Article | |
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15. | Steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT) in childhood. |
Patnaik SK, Upreti V, Dhull P. | |
J Pediatr Endocrinol Metab. 2014 Jul;27(7-8):737-44. doi: 10.1515/jpem-2013-0435. Review. | |
PMID: 24598831 [PubMed – indexed for MEDLINE] | |
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16. | Case report: When measured free T4 and free T3 may be misleading. Interference with free thyroid hormones measurements on Roche® and Siemens® platforms. |
Lewandowski KC, D?browska K, Lewi?ski A. | |
Thyroid Res. 2012 Oct 29;5(1):11. doi: 10.1186/1756-6614-5-11. | |
PMID: 23107155 [PubMed] Free PMC Article | |
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17. | [Hashimoto’s thyroiditis in children and adolescents]. |
Markovi? S, Kosti? G, Igrutinovi? Z, Vuleti? B. | |
Srp Arh Celok Lek. 2008 May-Jun;136(5-6):262-6. Serbian. | |
PMID: 18792623 [PubMed – indexed for MEDLINE] Free Article | |
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regarding the study in the following article please explain: CONCLUSION:
This study suggests that levothyroxine replacement decreases oxidant status and increases antioxidant status following the 6 months of levothyroxine replacement in hypothyroidism that develops in accordance with the HT.
Basically it is saying that it reduces inflammation.