Autoimmune thyroid diseases are the most common of the autoimmune diseases affecting industrialized societies. In addition, research is demonstrating their prevalence to be rising. In an attempt to pursue this phenomenon, today we discuss new literature associating EBV and parasites with Graves’ and Hashimoto’s. In addition, we will discuss other factors which may be associated in the pathogenesis of autoimmune thyroid disease.
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References:
1. | The role of Epstein-Barr virus infection in the development of autoimmune thyroid diseases. |
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2. | [Risk factors and pathogenesis of Hashimoto’s thyroiditis]. |
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3. | Thyrotropin Receptor Antibody (TRAb)-IgM Levels Are Markedly Higher Than TRAb-IgG Levels in Graves’ Disease Patients and Controls, and TRAb-IgM Production Is Related to Epstein-Barr Virus Reactivation. |
Kumata K, Nagata K, Matsushita M, Kuwamoto S, Kato M, Murakami I, Fukata S, Hayashi K. | |
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4. | Reactivation of persistent Epstein-Barr virus (EBV) causes secretion of thyrotropin receptor antibodies (TRAbs) in EBV-infected B lymphocytes with TRAbs on their surface. |
Nagata K, Nakayama Y, Higaki K, Ochi M, Kanai K, Matsushita M, Kuwamoto S, Kato M, Murakami I, Iwasaki T, Nanba E, Kimura H, Hayashi K. | |
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5. | Presence of Epstein-Barr virus-infected B lymphocytes with thyrotropin receptor antibodies on their surface in Graves’ disease patients and in healthy individuals. |
Nagata K, Higaki K, Nakayama Y, Miyauchi H, Kiritani Y, Kanai K, Matsushita M, Iwasaki T, Sugihara H, Kuwamoto S, Kato M, Murakami I, Nanba E, Kimura H, Hayashi K. | |
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6. | CD8+ T-Cell Deficiency, Epstein-Barr Virus Infection, Vitamin D Deficiency, and Steps to Autoimmunity: A Unifying Hypothesis. |
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7. | Naturally Occurring Subclinical Endotoxemia in Humans Alters Adaptive and Innate Immune Functions through Reduced MAPK and Increased STAT1 Phosphorylation. |
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8. | Infections and autoimmune thyroid diseases: parallel detection of antibodies against pathogens with proteomic technology. |
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9. | Association of active human herpesvirus-6 (HHV-6) infection with autoimmune thyroid gland diseases. |
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10. | Increase in Peripheral CD3-CD56brightCD16- Natural Killer Cells in Hashimoto’s Thyroiditis Associated with HHV-6 Infection. |
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11. | Virologic and immunologic evidence supporting an association between HHV-6 and Hashimoto’s thyroiditis. |
Caselli E, Zatelli MC, Rizzo R, Benedetti S, Martorelli D, Trasforini G, Cassai E, degli Uberti EC, Di Luca D, Dolcetti R. | |
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Nagata K, Okuno K, Ochi M, Kumata K, Sano H, Yoneda N, Ueyama J, Matsushita M, Kuwamoto S, Kato M, Murakami I, Kanzaki S, Hayashi K. | |
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Thanks for reading the research, sharing it with the public and putting your cutting edge programs into practice. I live in Nova Scotia and have been living with a very degraded level of health for several years. I look forward to continuing to educate myself via your website and YouTube offerings and plan to seek your professional help when the timing permits. Best Wishes to both of you!