Vitamin D: Why Your Levels Need To Be Normal

Vitamin D status is a very important topic. Once thought to only be critical in calcium metabolism, the systemic health benefits of normal Vitamin D levels are just now being realized.  In today’s broadcast we will highlight how Vitamin D interacts with the immune system, as many of our patients have immune disorders, and new frontiers in Vitamin D research.
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References:
1.Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer.
Sarkar S, Hewison M, Studzinski GP, Li YC, Kalia V.
Crit Rev Clin Lab Sci. 2015 Oct 19:1-14. [Epub ahead of print]
PMID: 26479950 [PubMed – as supplied by publisher]
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2.Anticancer Potential of Dietary Vitamin D and Ascorbic Acid: A Review.
Sunil Kumar BV, Singh S, Verma R.
Crit Rev Food Sci Nutr. 2015 Oct 19:0. [Epub ahead of print]
PMID: 26479551 [PubMed – as supplied by publisher]
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3.What’s new in hepatitis C virus infections in children?
Pawlowska M, Domagalski K, Pniewska A, Smok B, Halota W, Tretyn A.
World J Gastroenterol. 2015 Oct 14;21(38):10783-9. doi: 10.3748/wjg.v21.i38.10783. Review.
PMID: 26478670 [PubMed – in process]
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4.Ultraviolet radiation, vitamin D and multiple sclerosis.
Lucas RM, Byrne SN, Correale J, Ilschner S, Hart PH.
Neurodegener Dis Manag. 2015 Oct 19. [Epub ahead of print]
PMID: 26477548 [PubMed – as supplied by publisher]
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5.Metabolic effects of supplementation with vitamin D in type 2 diabetic patients with vitamin D deficiency.
Calvo-Romero JM, Ramiro-Lozano JM.
Diabetes Metab Syndr. 2015 Oct 9. pii: S1871-4021(15)30034-5. doi: 10.1016/j.dsx.2015.09.008. [Epub ahead of print]
PMID: 26476486 [PubMed – as supplied by publisher]
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6.Should we prescribe calcium or vitamin D supplements to treat or prevent osteoporosis?
Bolland MJ, Grey A, Reid IR.
Climacteric. 2015 Oct 16:1-10. [Epub ahead of print]
PMID: 26473773 [PubMed – as supplied by publisher]
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7.Vitamin D and hippocampal development-the story so far.
Lardner AL.
Front Mol Neurosci. 2015 Oct 7;8:58. doi: 10.3389/fnmol.2015.00058. eCollection 2015. Review.
PMID: 26468295 [PubMed] Free PMC Article
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8.The effects of vitamin D plus calcium supplementation on metabolic profiles, biomarkers of inflammation, oxidative stress and pregnancy outcomes in pregnant women at risk for pre-eclampsia.
Samimi M, Kashi M, Foroozanfard F, Karamali M, Bahmani F, Asemi Z, Hamidian Y, Talari HR, Esmaillzadeh A.
J Hum Nutr Diet. 2015 Oct 14. doi: 10.1111/jhn.12339. [Epub ahead of print]
PMID: 26467311 [PubMed – as supplied by publisher]
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9.The multiple sclerosis-associated regulatory variant rs10877013 affects expression of CYP27B1 and VDR under inflammatory or vitamin D stimuli.
Karaky M, Alcina A, Fedetz M, Barrionuevo C, Potenciano V, Delgado C, Izquierdo G, Matesanz F.
Mult Scler. 2015 Oct 14. pii: 1352458515610208. [Epub ahead of print]
PMID: 26466946 [PubMed – as supplied by publisher]
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10.Vitamin D Role in Hospitalized Children with Lower Tract Acute Respiratory Infections.
Cebey-López M, Pardo-Seco J, Gómez-Carballa A, Martinón-Torres N, Rivero-Calle I, Justicia A, Redondo L, Martinón-Sánchez JM, Martínez-Padilla MD, Giménez-Sánchez F, Salas A, Martinón-Torres F; GENDRES network.
J Pediatr Gastroenterol Nutr. 2015 Oct 9. [Epub ahead of print]
PMID: 26465790 [PubMed – as supplied by publisher]
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11.Threshold effects of vitamin D status on bone health in Chinese adolescents with low calcium intake.
Wu F, Laslett LL, Zhang Q.
J Clin Endocrinol Metab. 2015 Oct 14:jc20152849. [Epub ahead of print]
PMID: 26465394 [PubMed – as supplied by publisher]
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12.The effect of pre-diagnostic vitamin D supplementation on cancer survival in women: a cohort study within the UK Clinical Practice Research Datalink.
Jeffreys M, Redaniel MT, Martin RM.
BMC Cancer. 2015 Oct 12;15(1):670. doi: 10.1186/s12885-015-1684-0.
PMID: 26458897 [PubMed – in process] Free PMC Article
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13.Association of vitamin D receptor gene polymorphisms with polycystic ovary syndrome among Indian women.
Dasgupta S, Dutta J, Annamaneni S, Kudugunti N, Battini MR.
Indian J Med Res. 2015 Sep;142(3):276-85. doi: 10.4103/0971-5916.166587.
PMID: 26458343 [PubMed – in process] Free Article
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14.Comparison of two different vitamin D supplementation regimens with oral calcifediol in kidney transplant patients.
Barros X, Rodríguez NY, Fuster D, Rodas L, Esforzado N, Mazza A, Rubello D, Campos F, Tapias A, Torregrosa JV.
J Nephrol. 2015 Oct 10. [Epub ahead of print]
PMID: 26454858 [PubMed – as supplied by publisher]
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15.Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease.
Lucisano S, Arena A, Stassi G, Iannello D, Montalto G, Romeo A, Costantino G, Lupica R, Cernaro V, Santoro D, Buemi M.
Int J Endocrinol. 2015;2015:765364. doi: 10.1155/2015/765364. Epub 2015 Sep 15.
PMID: 26451144 [PubMed] Free PMC Article
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16.Vitamin D deficiency is associated with impaired disease control in asthma-COPD overlap syndrome patients.
Odler B, Ivancsó I, Somogyi V, Benke K, Tamási L, Gálffy G, Szalay B, Müller V.
Int J Chron Obstruct Pulmon Dis. 2015 Sep 24;10:2017-25. doi: 10.2147/COPD.S91654. eCollection 2015.
PMID: 26451099 [PubMed – in process] Free PMC Article
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17.High-Dose versus Low-Dose Vitamin D Supplementation and Arterial Stiffness among Individuals with Prehypertension and Vitamin D Deficiency.
Zaleski A, Panza G, Swales H, Arora P, Newton-Cheh C, Wang T, Thompson PD, Taylor B.
Dis Markers. 2015;2015:918968. doi: 10.1155/2015/918968. Epub 2015 Sep 16.
PMID: 26451070 [PubMed – in process] Free PMC Article
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18.The Apparent Relation between Plasma 25-Hydroxyvitamin D and Insulin Resistance Is Largely Attributable to Central Adiposity in Overweight and Obese Adults.
Wright CS, Weinheimer-Haus EM, Fleet JC, Peacock M, Campbell WW.
J Nutr. 2015 Oct 7. pii: jn220541. [Epub ahead of print]
PMID: 26446485 [PubMed – as supplied by publisher]
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19.Vitamin D Levels and Sociodemographic and Clinical Correlates in Individuals With Serious Mental Illness Admitted to an Acute Psychiatry Unit.
Chekuri L, Thapa PB, Turturro CL, Mittal D, Messias E.
Prim Care Companion CNS Disord. 2015 Apr 30;17(2). doi: 10.4088/PCC.14m01726. eCollection 2015.
PMID: 26445692 [PubMed] Free PMC Article
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20.Assessment of the feasibility of using sunlight exposure to obtain the recommended level of vitamin D in Canada.
Gill P, Kalia S.
CMAJ Open. 2015 Jul 17;3(3):E258-63. doi: 10.9778/cmajo.20140037. eCollection 2015 Jul-Sep.
PMID: 26442223 [PubMed] Free PMC Article
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