Ulcerative Colitis and Crohn’s disease: How Leaky Gut Syndrome and the Microbiome Influence These Diseases

The newest scientific literature regarding Ulcerative Colitis and Crohn’s Disease is extremely exciting as the scientific community is now becoming more aware of how the bacteria in our intestines and colon interplay with our immune system.  For some individuals who are genetically susceptible, this can manifest as Ulcerative Colitis and or Crohn’s Disease.  In today’s broadcast we will be discussing this new literature, and prospectively what it means for the inflammatory bowel disease sufferers going forward, and how doctors will be managing these conditions.
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1.Optimizing the Care and Health of Women with Inflammatory Bowel Disease.
Nee J, Feuerstein JD.
Gastroenterol Res Pract. 2015;2015:435820. doi: 10.1155/2015/435820. Epub 2015 May 21. Review.
PMID: 26089868 [PubMed] Free PMC Article
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2.Role of Rho kinase signal pathway in inflammatory bowel disease.
Huang Y, Xiao S, Jiang Q.
Int J Clin Exp Med. 2015 Mar 15;8(3):3089-97. eCollection 2015. Review.
PMID: 26064197 [PubMed] Free PMC Article
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3.Clinical trial development for biosimilars.
Alten R, Cronstein BN.
Semin Arthritis Rheum. 2015 Jun;44(6S):S2-S8. doi: 10.1016/j.semarthrit.2015.04.002. Review.
PMID: 26058550 [PubMed – as supplied by publisher] Free Article
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4.Contribution of the IL-17/IL-23 axis to the pathogenesis of inflammatory bowel disease.
C?tan? CS, Berindan Neagoe I, Cozma V, Magda? C, T?b?ran F, Dumitra?cu DL.
World J Gastroenterol. 2015 May 21;21(19):5823-5830. Review.
PMID: 26019446 [PubMed – as supplied by publisher] Free PMC Article
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5.Role of wireless capsule endoscopy in the follow-up of inflammatory bowel disease.
Mitselos IV, Christodoulou DK, Katsanos KH, Tsianos EV.
World J Gastrointest Endosc. 2015 Jun 10;7(6):643-51. doi: 10.4253/wjge.v7.i6.643. Review.
PMID: 26078832 [PubMed] Free PMC Article
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6.The exposome in inflammatory bowel disease.
Ananthakrishnan AN.
Trop Gastroenterol. 2014 Jul-Sep;35(3):135-40. Review.
PMID: 26012316 [PubMed – indexed for MEDLINE]
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7.Current therapy of pediatric Crohn’s disease.
Lahad A, Weiss B.
World J Gastrointest Pathophysiol. 2015 May 15;6(2):33-42. doi: 10.4291/wjgp.v6.i2.33. Review.
PMID: 25977836 [PubMed] Free PMC Article
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8.C-Reactive Protein, Fecal Calprotectin, and Stool Lactoferrin for Detection of Endoscopic Activity in Symptomatic Inflammatory Bowel Disease Patients: A Systematic Review and Meta-Analysis.
Mosli MH, Zou G, Garg SK, Feagan SG, MacDonald JK, Chande N, Sandborn WJ, Feagan BG.
Am J Gastroenterol. 2015 Jun;110(6):802-819. doi: 10.1038/ajg.2015.120. Epub 2015 May 12. Review.
PMID: 25964225 [PubMed – as supplied by publisher]
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9.Optimizing the use of anti-tumor necrosis factor in the management of patients with Crohn’s disease.
Nguyen DL, Flores S, Sassi K, Bechtold ML, Nguyen ET, Parekh NK.
Ther Adv Chronic Dis. 2015 May;6(3):147-54. doi: 10.1177/2040622315579621. Review.
PMID: 25954499 [PubMed] Free PMC Article
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10.Optimizing the use of thiopurines in inflammatory bowel disease.
Goel RM, Blaker P, Mentzer A, Fong SC, Marinaki AM, Sanderson JD.
Ther Adv Chronic Dis. 2015 May;6(3):138-46. doi: 10.1177/2040622315579063. Review.
PMID: 25954498 [PubMed] Free PMC Article
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11.Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut.
Endale M, Aksoylar HI, Hoebe K.
Mediators Inflamm. 2015;2015:436017. doi: 10.1155/2015/436017. Epub 2015 Apr 7. Review.
PMID: 25944983 [PubMed – in process] Free PMC Article
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12.The relationship between intestinal parasites and some immune-mediated intestinal conditions.
Mohammadi R, Hosseini-Safa A, Ehsani Ardakani MJ, Rostami-Nejad M.
Gastroenterol Hepatol Bed Bench. 2015 Spring;8(2):123-31. Review.
PMID: 25926937 [PubMed] Free PMC Article
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13.Intestinal microbiota as modulators of the immune system and neuroimmune system: impact on the host health and homeostasis.
Maranduba CM, De Castro SB, de Souza GT, Rossato C, da Guia FC, Valente MA, Rettore JV, Maranduba CP, de Souza CM, do Carmo AM, Macedo GC, Silva Fde S.
J Immunol Res. 2015;2015:931574. doi: 10.1155/2015/931574. Epub 2015 Feb 22. Review.
PMID: 25759850 [PubMed – in process] Free PMC Article
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14.The route to pathologies in chronic inflammatory diseases characterized by T helper type 2 immune cells.
Jovanovic K, Siebeck M, Gropp R.
Clin Exp Immunol. 2014 Nov;178(2):201-11. doi: 10.1111/cei.12409. Review.
PMID: 24981014 [PubMed – indexed for MEDLINE]
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