The Thin Hashimoto’s Patient

Today we will be discussing what is termed fear avoidance syndrome or kinesophobia as it pertains to fibromyalgia. This is a well acknowledged condition that applies to patients with chronic pain conditions including but not limited to fibromyalgia. We will discuss  how we handle this issue in our fibro sufferers as well as what this means relative to prognosis.

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1.Autoimmunity affects health-related quality of life in patients with Hashimoto’s thyroiditis.
Bektas Uysal H, Ayhan M.
Kaohsiung J Med Sci. 2016 Aug;32(8):427-33. doi: 10.1016/j.kjms.2016.06.006.
PMID: 27523457 [PubMed – in process] Free Article
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2.Hashimoto’s thyroiditis affects symptom load and quality of life unrelated to hypothyroidism: a prospective case-control study in women undergoing thyroidectomy for benign goiter.
Ott J, Promberger R, Kober F, Neuhold N, Tea M, Huber JC, Hermann M.
Thyroid. 2011 Feb;21(2):161-7. doi: 10.1089/thy.2010.0191. Erratum in: Thyroid. 2011 Apr;21(4):467.
PMID: 21186954 [PubMed – indexed for MEDLINE]
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3.Cognitive and affective dysfunctions in autoimmune thyroiditis.
Leyhe T, Müssig K.
Brain Behav Immun. 2014 Oct;41:261-6. doi: 10.1016/j.bbi.2014.03.008. Review.
PMID: 24685840 [PubMed – indexed for MEDLINE]
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4.Structural and functional MRI study of the brain, cognition and mood in long-term adequately treated Hashimoto’s thyroiditis.
Quinque EM, Karger S, Arélin K, Schroeter ML, Kratzsch J, Villringer A.
Psychoneuroendocrinology. 2014 Apr;42:188-98. doi: 10.1016/j.psyneuen.2014.01.015.
PMID: 24636515 [PubMed – indexed for MEDLINE]
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5.Thyroid peroxidase antibody positivity is associated with symptomatic distress in patients with Hashimoto’s thyroiditis.
Müssig K, Künle A, Säuberlich AL, Weinert C, Ethofer T, Saur R, Klein R, Häring HU, Klingberg S, Gallwitz B, Leyhe T.
Brain Behav Immun. 2012 May;26(4):559-63. doi: 10.1016/j.bbi.2012.01.006.
PMID: 22285302 [PubMed – indexed for MEDLINE]
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6.The prevalence of affective disorder and in particular of a rapid cycling of bipolar disorder in patients with abnormal thyroid function tests.
Oomen HA, Schipperijn AJ, Drexhage HA.
Clin Endocrinol (Oxf). 1996 Aug;45(2):215-23.
PMID: 8881455 [PubMed – indexed for MEDLINE]
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7.Effects of thyroid status on thyroid autoimmunity expression in euthyroid and hypothyroid patients with Hashimoto’s thyroiditis.
Rieu M, Richard A, Rosilio M, Laplanche S, Ropion V, Fombeur JP, Berrod JL.
Clin Endocrinol (Oxf). 1994 Apr;40(4):529-35.
PMID: 8187321 [PubMed – indexed for MEDLINE]
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8.Increased prevalence of antibodies to central nervous system tissue and gangliosides in Hashimoto’s thyroiditis compared to other thyroid illnesses.
Müssig K, Leyhe T, Holzmüller S, Klein R, Weinert C, Saur R, Klingberg S, Häring HU, Gallwitz B.
Psychoneuroendocrinology. 2009 Sep;34(8):1252-6. doi: 10.1016/j.psyneuen.2009.03.011.
PMID: 19375868 [PubMed – indexed for MEDLINE]
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9.Increased occurrence of weaknesses in attention testing in patients with Hashimoto’s thyroiditis compared to patients with other thyroid illnesses.
Leyhe T, Müssig K, Weinert C, Laske C, Häring HU, Saur R, Klingberg S, Gallwitz B.
Psychoneuroendocrinology. 2008 Nov;33(10):1432-6. doi: 10.1016/j.psyneuen.2008.08.009.
PMID: 18819753 [PubMed – indexed for MEDLINE]
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10.Epitope recognition patterns of thyroid peroxidase autoantibodies in healthy individuals and patients with Hashimoto’s thyroiditis*.
Nielsen CH, Brix TH, Gardas A, Banga JP, Hegedüs L.
Clin Endocrinol (Oxf). 2008 Oct;69(4):664-8. doi: 10.1111/j.1365-2265.2008.03245.x.
PMID: 18363888 [PubMed – indexed for MEDLINE]
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