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Today we will be discussing Traumatic Brain Injury and PCS and factors perpetuating symptoms of the head injury. Today we will focus particularly on how gastrointestinal barrier integrity is compromised as well as how the mitochondria (considered the powerhouse of our cells that generate cellular energy) are negatively affected by brain injury.
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References:
| 1. | Factors Influencing Clinical Correlates of Chronic Traumatic Encephalopathy (CTE): a Review. |
| Asken BM, Sullan MJ, Snyder AR, Houck ZM, Bryant VE, Hizel LP, McLaren ME, Dede DE, Jaffee MS, DeKosky ST, Bauer RM. | |
| Neuropsychol Rev. 2016 Aug 25. [Epub ahead of print] Review. | |
| PMID: 27561662 [PubMed – as supplied by publisher] | |
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| 2. | Cortisol-induced immune suppression by a blockade of lymphocyte egress in traumatic brain injury. |
| Dong T, Zhi L, Bhayana B, Wu MX. | |
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| 3. | Patients “At Risk” of Suffering from Persistent Complaints after Mild Traumatic Brain Injury: The Role of Coping, Mood Disorders, and Post-Traumatic Stress. |
| Scheenen ME, Spikman JM, de Koning ME, van der Horn HJ, Roks G, Hageman G, van der Naalt J. | |
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| 4. | Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterations. |
| Chen H, Chan YL, Nguyen LT, Mao Y, De Rosa A, Beh IT, Chee C, Oliver B, Herok G, Saad S, Gorrie C. | |
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| 5. | Systems Biology, Neuroimaging, Neuropsychology, Neuroconnectivity and Traumatic Brain Injury. |
| Bigler ED. | |
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| 6. | Combat blast related traumatic brain injury (TBI): Decade of recognition; promise of progress. |
| DePalma RG, Hoffman SW. | |
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| 7. | Treatment of surgical brain injury by immune tolerance induced by intrathymic and hepatic portal vein injection of brain antigens. |
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| 8. | Cerebral Perfusion changes in Post-Concussion Syndrome: A prospective controlled cohort study. |
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| 9. | Post-traumatic administration of the p53 inactivator pifithrin-? oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury. |
| Yang LY, Greig NH, Huang YN, Hsieh TH, Tweedie D, Yu QS, Hoffer BJ, Luo Y, Kao YC, Wang JY. | |
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| 10. | Early prediction of outcome after severe traumatic brain injury: a simple and practical model. |
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| 11. | Disrupted white matter microstructure and mood disorders following traumatic brain injury. |
| Spitz G, Alway YJ, Gould K, Ponsford J. | |
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| 12. | The gut in trauma. |
| Patel JJ, Rosenthal MD, Miller KR, Martindale RG. | |
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| 13. | Brain injury induces specific changes in the caecal microbiota of mice via altered autonomic activity and mucoprotein production. |
| Houlden A, Goldrick M, Brough D, Vizi ES, Lénárt N, Martinecz B, Roberts IS, Denes A. | |
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| PMID: 27060191 [PubMed – as supplied by publisher] Free Article | |
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| 14. | Brain-gut axis and pentadecapeptide BPC 157. Theoretical and practical implications. |
| Predrag S, Sven S, Rudolf R, Danijela K, Lovorka BV, Domagoj D, Tihomir G, Sanja S, Goran Z, Dalibor C, Goran M, Iva R, Mario S, Marko B, Neven S, Zoran K, Martina LB, Igor F, Dinko SR, Josipa V. | |
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| 15. | Traumatic Brain Injury and the Effect on the Brain-Gut Axis. |
| Kharrazian D. | |
| Altern Ther Health Med. 2015 Aug;21 Suppl 3:28-32. | |
| PMID: 26348611 [PubMed – in process] | |
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| 16. | The gut reaction to traumatic brain injury. |
| Katzenberger RJ, Ganetzky B, Wassarman DA. | |
| Fly (Austin). 2015;9(2):68-74. doi: 10.1080/19336934.2015.1085623. | |
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| 17. | Labetalol Prevents Intestinal Dysfunction Induced by Traumatic Brain Injury. |
| Lang Y, Fu F, Sun D, Xi C, Chen F. | |
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| PMID: 26186619 [PubMed – indexed for MEDLINE] Free PMC Article | |
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| 18. | Thinking outside the brain for cognitive improvement: Is peripheral immunomodulation on the way? |
| Zheng X, Zhang X, Kang A, Ran C, Wang G, Hao H. | |
| Neuropharmacology. 2015 Sep;96(Pt A):94-104. doi: 10.1016/j.neuropharm.2014.06.0 | |
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| 19. | Ghrelin attenuates brain injury after traumatic brain injury and uncontrolled hemorrhagic shock in rats. |
| Qi L, Cui X, Dong W, Barrera R, Nicastro J, Coppa GF, Wang P, Wu R. | |
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| PMID: 22160303 [PubMed – indexed for MEDLINE] Free PMC Article | |
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