Today’s broadcast is covering Reflex Sympathetic Dystrophy (RSD) or more specifically Complex Regional Pain Syndrome type 1 (CRPS-1). We will also discuss nerve related injuries classified as Complex Regional Pain Syndrome type 2 (CRPS-2) formerly known as causalgia. Many patients with chronic unrelenting pain following trivial or significant trauma classified under these umbrellas feel dejected with a lack of acceptance regarding their condition as well as there being a lack of answers. In today’s broadcast we will describe the mechanisms as to why RSD/CRPS occurs and discuss treatment options.
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References:
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Midbari A, Suzan E, Adler T, Melamed E, Norman D, Vulfsons S, Eisenberg E. | |
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PMID: 27037439 [PubMed – in process] | |
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2. | Complex regional pain syndrome in children: incidence and clinical characteristics. |
Abu-Arafeh H, Abu-Arafeh I. | |
Arch Dis Child. 2016 Mar 22. pii: archdischild-2015-310233. doi: 10.1136/archdischild-2015- | |
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7. | [Complex regional pain syndrome type 1: negating the myth]. |
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10. | Homocysteine-induced attenuation of vascular endothelium-dependent hyperalgesia in the rat. |
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11. | Intrinsic brain networks normalize with treatment in pediatric complex regional pain syndrome. |
Becerra L, Sava S, Simons LE, Drosos AM, Sethna N, Berde C, Lebel AA, Borsook D. | |
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12. | Interhemispheric somatosensory differences in chronic pain reflect abnormality of the healthy side. |
Di Pietro F, Stanton TR, Moseley GL, Lotze M, McAuley JH. | |
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13. | Primary somatosensory cortex function in complex regional pain syndrome: a systematic review and meta-analysis. |
Di Pietro F, McAuley JH, Parkitny L, Lotze M, Wand BM, Moseley GL, Stanton TR. | |
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15. | Patterns of cortical reorganization parallel impaired tactile discrimination and pain intensity in complex regional pain syndrome. |
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16. | Complex regional pain syndrome: a comprehensive and critical review. |
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17. | Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy? |
Oaklander AL, Fields HL. | |
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18. | Evidence of focal small-fiber axonal degeneration in complex regional pain syndrome-I (reflex sympathetic dystrophy). |
Oaklander AL, Rissmiller JG, Gelman LB, Zheng L, Chang Y, Gott R. | |
Pain. 2006 Feb;120(3):235-43. Epub 2006 Jan 19. | |
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19. | Skin biopsy in complex regional pain syndrome: case series and literature review. |
Kharkar S, Venkatesh YS, Grothusen JR, Rojas L, Schwartzman RJ. | |
Pain Physician. 2012 May-Jun;15(3):255-66. | |
PMID: 22622910 [PubMed – indexed for MEDLINE] Free Article | |
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20. | Topical combinations aimed at treating microvascular dysfunction reduce allodynia in rat models of CRPS-I and neuropathic pain. |
Ragavendran JV, Laferrière A, Xiao WH, Bennett GJ, Padi SS, Zhang J, Coderre TJ. | |
J Pain. 2013 Jan;14(1):66-78. doi: 10.1016/j.jpain.2012.10.004. | |
PMID: 23273834 [PubMed – indexed for MEDLINE] Free PMC Article | |
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21. | Treatment of complex regional pain syndrome type I with bisphosphonates. |
Giusti A, Bianchi G. | |
RMD Open. 2015 Aug 15;1(Suppl 1):e000056. doi: 10.1136/rmdopen-2015-000056. eCollection 2015. Review. | |
PMID: 26557377 [PubMed] Free PMC Article | |
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22. | Immunotherapy Prospects for Painful Small-fiber Sensory Neuropathies and Ganglionopathies. |
Oaklander AL. | |
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23. | Differential Efficacy of Ketamine in the Acute versus Chronic Stages of Complex Regional Pain Syndrome in Mice. |
Tajerian M, Leu D, Yang P, Huang TT, Kingery WS, Clark JD. | |
Anesthesiology. 2015 Dec;123(6):1435-47. doi: 10.1097/ALN.0000000000000889. | |
PMID: 26492479 [PubMed – indexed for MEDLINE] | |
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24. | Lumbar Sympathetic Block with Botulinum Toxin Type B for Complex Regional Pain Syndrome: A Case Study. |
Choi E, Cho CW, Kim HY, Lee PB, Nahm FS. | |
Pain Physician. 2015 Sep-Oct;18(5):E911-6. | |
PMID: 26431145 [PubMed – indexed for MEDLINE] Free Article | |
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25. | Neurogenic neuroinflammation in fibromyalgia and complex regional pain syndrome. |
Littlejohn G. | |
Nat Rev Rheumatol. 2015 Nov;11(11):639-48. doi: 10.1038/nrrheum.2015.100. Epub 2015 Aug 4. Review. | |
PMID: 26241184 [PubMed – indexed for MEDLINE] | |
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26. | Comparison of tonic spinal cord stimulation, high-frequency and burst stimulation in patients with complex regional pain syndrome: a double-blind, randomised placebo controlled trial. |
Kriek N, Groeneweg JG, Stronks DL, Huygen FJ. | |
BMC Musculoskelet Disord. 2015 Aug 25;16:222. doi: 10.1186/s12891-015-0650-y. | |
PMID: 26303326 [PubMed – indexed for MEDLINE] Free PMC Article | |
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27. | Plasma Exchange Therapy in Patients with Complex Regional Pain Syndrome. |
Aradillas E, Schwartzman RJ, Grothusen JR, Goebel A, Alexander GM. | |
Pain Physician. 2015 Jul-Aug;18(4):383-94. | |
PMID: 26218942 [PubMed – indexed for MEDLINE] Free Article | |
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