PTSD and its Role in Fibromyalgia

Fibromyalgia is a common condition, that lacks a gold standard treatment.  Studies have shown that medications are often minimally effective, and that simple interventions like exercise may be of more benefit.  Tremendous confusion surrounds the diagnosis of Fibromyalgia, for both doctors and patients.

The three major underlying “triggers” of fibromyalgia include stress, inflammation, and small fiber peripheral neuropathy.  In our clinical experience, as well as the literature, a significant percentage of fibromyalgia patients have been exposed to horrific circumstances, and the long lasting effects of this stress in the form of Post Traumatic Stress Disorder (PTSD) are important to not only recognize, but also to use as a tool in the aim of helping the Fibromyalgia patient improve.

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1.Self-reported childhood maltreatment, lifelong traumatic events and mental disorders in fibromyalgia syndrome: a comparison of US and German outpatients.
Häuser W, Hoffmann EM, Wolfe F, Worthing AB, Stahl N, Rothenberg R, Walitt B.
Clin Exp Rheumatol. 2015 Mar-Apr;33(1 Suppl 88):86-92. Epub 2015 Mar 18.
PMID: 25786049 [PubMed – in process]
Related citations
2.GILZ: Glitzing up our understanding of the glucocorticoid receptor in psychopathology.
Thiagarajah AS, Eades LE, Thomas PR, Guymer EK, Morand EF, Clarke DM, Leech M.
Brain Res. 2014 Jul 29;1574:60-9. doi: 10.1016/j.brainres.2014.06.008. Epub 2014 Jun 12. Review.
PMID: 24931768 [PubMed – indexed for MEDLINE]
Related citations
3.A cross-sectional survey assessing sources of movement-related fear among people with fibromyalgia syndrome.
Russek L, Gardner S, Maguire K, Stevens C, Brown EZ, Jayawardana V, Mondal S.
Clin Rheumatol. 2014 Jan 31. [Epub ahead of print]
PMID: 24481649 [PubMed – as supplied by publisher]
Related citations
4.Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis.
Afari N, Ahumada SM, Wright LJ, Mostoufi S, Golnari G, Reis V, Cuneo JG.
Psychosom Med. 2014 Jan;76(1):2-11. doi: 10.1097/PSY.0000000000000010. Epub 2013 Dec 12. Review.
PMID: 24336429 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations
5.Associations between body mass index, post-traumatic stress disorder, and child maltreatment in young women.
Duncan AE, Sartor CE, Jonson-Reid M, Munn-Chernoff MA, Eschenbacher MA, Diemer EW, Nelson EC, Waldron M, Bucholz KK, Madden PA, Heath AC.
Child Abuse Negl. 2015 Mar 11. pii: S0145-2134(15)00052-6. doi: 10.1016/j.chiabu.2015.02.007. [Epub ahead of print]
PMID: 25770346 [PubMed – as supplied by publisher]
Related citations
6.An epidemiological overview of child sexual abuse.
Singh MM, Parsekar SS, Nair SN.
J Family Med Prim Care. 2014 Oct-Dec;3(4):430-5. doi: 10.4103/2249-4863.148139. Review.
PMID: 25657958 [PubMed] Free PMC Article
Related citations
7.[Conditions, controversies and contradictions between Central Sensitivity Syndrome and Depressive Disorders].
Maresca T, Covini E, Mato AM.
Vertex. 2013 Sep-Oct;24(111):373-91. Spanish.
PMID: 24312923 [PubMed – indexed for MEDLINE]
Related citations
8.Vulnerability to traumatic stress in fibromyalgia patients: 19 month follow-up after the great East Japan disaster.
Usui C, Hatta K, Aratani S, Yagishita N, Nishioka K, Okamura S, Itoh K, Yamano Y, Nakamura H, Asukai N, Nakajima T, Nishioka K.
Arthritis Res Ther. 2013 Sep 23;15(5):R130. doi: 10.1186/ar4310.
PMID: 24286267 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations
9.Dissociative depression among women with fibromyalgia or rheumatoid arthritis.
Kilic O, Sar V, Taycan O, Aksoy-Poyraz C, Erol TC, Tecer O, Emul MH, Ozmen M.
J Trauma Dissociation. 2014;15(3):285-302. doi: 10.1080/15299732.2013.844218.
PMID: 24228798 [PubMed – indexed for MEDLINE]
Related citations
10.Posttraumatic stress disorder in fibromyalgia syndrome: prevalence, temporal relationship between posttraumatic stress and fibromyalgia symptoms, and impact on clinical outcome.
Häuser W, Galek A, Erbslöh-Möller B, Köllner V, Kühn-Becker H, Langhorst J, Petermann F, Prothmann U, Winkelmann A, Schmutzer G, Brähler E, Glaesmer H.
Pain. 2013 Aug;154(8):1216-23. doi: 10.1016/j.pain.2013.03.034. Epub 2013 Apr 2.
PMID: 23685006 [PubMed – indexed for MEDLINE]
Related citations
11.Alcohol dependence as a chronic pain disorder.
Egli M, Koob GF, Edwards S.
Neurosci Biobehav Rev. 2012 Nov;36(10):2179-92. doi: 10.1016/j.neubiorev.2012.07.010. Epub 2012 Sep 11. Review.
PMID: 22975446 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations
12.FMRI reveals abnormal central processing of sensory and pain stimuli in ill Gulf War veterans.
Gopinath K, Gandhi P, Goyal A, Jiang L, Fang Y, Ouyang L, Ganji S, Buhner D, Ringe W, Spence J, Biggs M, Briggs R, Haley R.
Neurotoxicology. 2012 Jun;33(3):261-71. doi: 10.1016/j.neuro.2012.01.014. Epub 2012 Feb 4.
PMID: 22327017 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations
13.Holocaust survivors: the pain behind the agony. Increased prevalence of fibromyalgia among Holocaust survivors.
Ablin JN, Cohen H, Eisinger M, Buskila D.
Clin Exp Rheumatol. 2010 Nov-Dec;28(6 Suppl 63):S51-6. Epub 2010 Dec 22.
PMID: 21176421 [PubMed – indexed for MEDLINE]
Related citations
14.Nondermatomal somatosensory deficits: overview of unexplainable negative sensory phenomena in chronic pain patients.
Mailis-Gagnon A, Nicholson K.
Curr Opin Anaesthesiol. 2010 Oct;23(5):593-7. doi: 10.1097/ACO.0b013e32833dd01c. Review.
PMID: 20657277 [PubMed – indexed for MEDLINE]
Related citations
15.Childhood maltreatment and diurnal cortisol patterns in women with chronic pain.
Nicolson NA, Davis MC, Kruszewski D, Zautra AJ.
Psychosom Med. 2010 Jun;72(5):471-80. doi: 10.1097/PSY.0b013e3181d9a104. Epub 2010 May 13.
PMID: 20467005 [PubMed – indexed for MEDLINE]
Related citations
16.Health consequences of childhood sexual abuse.
Wilson DR.
Perspect Psychiatr Care. 2010 Jan;46(1):56-64. doi: 10.1111/j.1744-6163.2009.00238.x. Review.
PMID: 20051079 [PubMed – indexed for MEDLINE]
Related citations
17.Etiopathogenetic mechanisms of fibromyalgia syndrome.
Stisi S, Cazzola M, Buskila D, Spath M, Giamberardino MA, Sarzi-Puttini P, Arioli G, Alciati A, Leardini G, Gorla R, Marsico A, Ceccherelli F, Bazzichi L, Carignola R, Gracely RH, Salaffi F, Marinangeli F, Torta R, Di Franco M, Biasi G, Cassisi G, Casale R, Altomonte L, Atzeni F; Italian Fibromyalgia Network.
Reumatismo. 2008 Jul-Sep;60 Suppl 1:25-35.
PMID: 18852906 [PubMed – indexed for MEDLINE]
Related citations
18.Somatoform dissociation and traumatic experiences in patients with rheumatoid arthritis and fibromyalgia.
Näring GW, van Lankveld W, Geenen R.
Clin Exp Rheumatol. 2007 Nov-Dec;25(6):872-7.
PMID: 18173922 [PubMed – indexed for MEDLINE]
Related citations
19.Coping styles in fibromyalgia: effect of co-morbid posttraumatic stress disorder.
Ablin JN, Cohen H, Neumann L, Kaplan Z, Buskila D.
Rheumatol Int. 2008 May;28(7):649-56. Epub 2007 Dec 6.
PMID: 18058105 [PubMed – indexed for MEDLINE]
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20.Physical activity protects male patients with post-traumatic stress disorder from developing severe fibromyalgia.
Arnson Y, Amital D, Fostick L, Silberman A, Polliack ML, Zohar J, Rubinow A, Amital H.
Clin Exp Rheumatol. 2007 Jul-Aug;25(4):529-33.
PMID: 17888207 [PubMed – indexed for MEDLINE]
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21.The hypothalamo-pituitary-adrenal axis in chronic fatigue syndrome and fibromyalgia syndrome.
Tanriverdi F, Karaca Z, Unluhizarci K, Kelestimur F.
Stress. 2007 Mar;10(1):13-25. Review.
PMID: 17454963 [PubMed – indexed for MEDLINE]
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