Psoriasis and Rosacea, are these disorders stemming from the gut?

Today we are discussing skin conditions and the latest research regarding lack of bacterial balance in the gut and its connection to disorders such as psoriasis and rosacea.  The information presented today is exciting, as the argument for the gut being a causal mechanism and generator of these conditions is growing stronger.
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1.Decreased bacterial diversity characterizes the altered gut microbiota in patients with psoriatic arthritis, resembling dysbiosis in inflammatory bowel disease.
Scher JU, Ubeda C, Artacho A, Attur M, Isaac S, Reddy SM, Marmon S, Neimann A, Brusca S, Patel T, Manasson J, Pamer EG, Littman DR, Abramson SB.
Arthritis Rheumatol. 2015 Jan;67(1):128-39. doi: 10.1002/art.38892.
PMID: 25319745 [PubMed – indexed for MEDLINE]
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2.Skin microbiome and skin disease: the example of rosacea.
Picardo M, Ottaviani M.
J Clin Gastroenterol. 2014 Nov-Dec;48 Suppl 1:S85-6. doi: 10.1097/MCG.0000000000000241. Review.
PMID: 25291137 [PubMed – indexed for MEDLINE]
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3.The immunomodulatory role of bile acids.
Sipka S, Bruckner G.
Int Arch Allergy Immunol. 2014;165(1):1-8. doi: 10.1159/000366100. Epub 2014 Sep 24. Review.
PMID: 25277277 [PubMed – indexed for MEDLINE]
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4.Effect of glucagon-like peptide-1 receptor agonists in patients with psoriasis.
Al-Badri MR, Azar ST.
Ther Adv Endocrinol Metab. 2014 Apr;5(2):34-8. doi: 10.1177/2042018814543483. Review.
PMID: 25152810 [PubMed] Free PMC Article
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5.Biologic therapy improves psoriasis by decreasing the activity of monocytes and neutrophils.
Yamanaka K, Umezawa Y, Yamagiwa A, Saeki H, Kondo M, Gabazza EC, Nakagawa H, Mizutani H.
J Dermatol. 2014 Aug;41(8):679-85. doi: 10.1111/1346-8138.12560.
PMID: 25099154 [PubMed – in process]
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6.The microbiome and psoriatic arthritis.
Eppinga H, Konstantinov SR, Peppelenbosch MP, Thio HB.
Curr Rheumatol Rep. 2014 Mar;16(3):407. doi: 10.1007/s11926-013-0407-2. Review.
PMID: 24474190 [PubMed – indexed for MEDLINE]
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7.Th17 cells in immunity and autoimmunity.
Bedoya SK, Lam B, Lau K, Larkin J 3rd.
Clin Dev Immunol. 2013;2013:986789. doi: 10.1155/2013/986789. Epub 2013 Dec 26. Review.
PMID: 24454481 [PubMed – indexed for MEDLINE] Free PMC Article
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8.Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut.
Groeger D, O’Mahony L, Murphy EF, Bourke JF, Dinan TG, Kiely B, Shanahan F, Quigley EM.
Gut Microbes. 2013 Jul-Aug;4(4):325-39. doi: 10.4161/gmic.25487. Epub 2013 Jun 21.
PMID: 23842110 [PubMed – indexed for MEDLINE] Free PMC Article
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9.Microscopic gut inflammation in axial spondyloarthritis: a multiparametric predictive model.
Van Praet L, Van den Bosch FE, Jacques P, Carron P, Jans L, Colman R, Glorieus E, Peeters H, Mielants H, De Vos M, Cuvelier C, Elewaut D.
Ann Rheum Dis. 2013 Mar;72(3):414-7. doi: 10.1136/annrheumdis-2012-202135. Epub 2012 Nov 8.
PMID: 23139267 [PubMed – indexed for MEDLINE]
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10.Quality of life in patients with immune-mediated inflammatory diseases.
Russell AS, Gulliver WP, Irvine EJ, Albani S, Dutz JP.
J Rheumatol Suppl. 2011 Nov;88:7-19. doi: 10.3899/jrheum.110899. Review.
PMID: 22045973 [PubMed – indexed for MEDLINE]
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11.Gastric bypass surgery: improving psoriasis through a GLP-1-dependent mechanism?
Faurschou A, Zachariae C, Skov L, Vilsbøll T, Knop FK.
Med Hypotheses. 2011 Dec;77(6):1098-101. doi: 10.1016/j.mehy.2011.09.011. Epub 2011 Oct 2.
PMID: 21968278 [PubMed – indexed for MEDLINE]
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12.The life and death of epithelia during inflammation: lessons learned from the gut.
Koch S, Nusrat A.
Annu Rev Pathol. 2012;7:35-60. doi: 10.1146/annurev-pathol-011811-120905. Epub 2011 Aug 12. Review.
PMID: 21838548 [PubMed – indexed for MEDLINE]
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13.Psoriatic disease–from skin to bone.
Ritchlin C.
Nat Clin Pract Rheumatol. 2007 Dec;3(12):698-706. Review.
PMID: 18037929 [PubMed – indexed for MEDLINE]
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14.Triggering psoriasis: the role of infections and medications.
Fry L, Baker BS.
Clin Dermatol. 2007 Nov-Dec;25(6):606-15. Review.
PMID: 18021899 [PubMed – indexed for MEDLINE]
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15.Patient-reported treatment satisfaction and choice of dosing frequency with biologic treatment for moderate to severe plaque psoriasis.
Zhang M, Brenneman SK, Carter CT, Essoi BL, Farahi K, Johnson MP, Lee S, Olson WH.
Patient Prefer Adherence. 2015 Jun 16;8:777-84. doi: 10.2147/PPA.S85773. eCollection 2015.
PMID: 26124643 [PubMed] Free PMC Article
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16.A multicenter, non-interventional study to evaluate patient-reported experiences of living with psoriasis.
Pariser D, Schenkel B, Carter C, Farahi K, Brown TM, Ellis CN; Psoriasis Patient Interview Study Group.
J Dermatolog Treat. 2015 Jul 3:1-8. [Epub ahead of print]
PMID: 26138406 [PubMed – as supplied by publisher]
17.Depression’s multiple comorbidities explained by (neuro)inflammatory and oxidative & nitrosative stress pathways.
Maes M, Kubera M, Obuchowiczwa E, Goehler L, Brzeszcz J.
Neuro Endocrinol Lett. 2011;32(1):7-24. Review.
PMID: 21407167 [PubMed – indexed for MEDLINE]
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18.Vasoactive Intestinal Peptide in Early Spondyloarthritis: Low Serum Levels as a Potential Biomarker for Disease Severity.
Seoane IV, Tomero E, Martínez C, Garcia-Vicuña R, Juarranz Y, Lamana A, Ocón E, Ortiz AM, Gómez-León N, González-Álvaro I, Gomariz RP.
J Mol Neurosci. 2015 Jul;56(3):577-84. doi: 10.1007/s12031-015-0517-6. Epub 2015 Feb 25.
PMID: 25711477 [PubMed – in process] Free PMC Article
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19.GLP-1: benefits beyond pancreas.
Muscogiuri G, Cignarelli A, Giorgino F, Prodram F, Santi D, Tirabassi G, Balercia G, Modica R, Faggiano A, Colao A.
J Endocrinol Invest. 2014 Aug 9. [Epub ahead of print]
PMID: 25107343 [PubMed – as supplied by publisher]
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20.Helicobacter pylori infection and skin disorders.
Kutlubay Z, Zara T, Engin B, Serdaro?lu S, Tüzün Y, Yilmaz E, Eren B.
Hong Kong Med J. 2014 Aug;20(4):317-24. doi: 10.12809/hkmj134174. Epub 2014 Jul 18. Review.
PMID: 25045884 [PubMed – indexed for MEDLINE] Free Article
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21.[Intestinal strongyloidiasis in a psoriasis patient with diabetes].
Iraz M, Karaman U, Topukçu B, Doymaz MZ.
Turkiye Parazitol Derg. 2014 Jun;38(2):127-30. doi: 10.5152/tpd.2014.3304. Turkish.
PMID: 25016122 [PubMed – indexed for MEDLINE] Free Article
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