POTS is a condition that can be associated with other chronic conditions such as Fibromyalgia, Chronic Fatigue Syndrome, Anxiety, irritable bowel symptoms, and Lyme Disease. In today’s broadcast we will discuss how POTS can be an independent cause of fatigue, summarize the current treatments for this condition, but also expand upon new research demonstrating an autoimmune component that may be driving POTS. Please enjoy
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References:
| 1. | A tale of two syndromes: Lyme disease preceding postural orthostatic tachycardia syndrome. |
| Noyes AM, Kluger J. | |
| Ann Noninvasive Electrocardiol. 2015 Jan;20(1):82-6. doi: 10.1111/anec.12158. Epub 2014 May 15. | |
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| 2. | Postural orthostatic tachycardia syndrome (POTS): association with Ehlers-Danlos syndrome and orthopaedic considerations. |
| Grigoriou E, Boris JR, Dormans JP. | |
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| 3. | An assessment of fatigue in patients with postural orthostatic tachycardia syndrome. |
| Wise S, Ross A, Brown A, Evans M, Jason L. | |
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| 4. | Menstrual cycle phase does not affect sympathetic neural activity in women with postural orthostatic tachycardia syndrome. |
| Stickford AS, VanGundy TB, Levine BD, Fu Q. | |
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| 5. | A cross-sectional study on upright heart rate and BP changing characteristics: basic data for establishing diagnosis of postural orthostatic tachycardia syndrome and orthostatic hypertension. |
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| 6. | Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort. |
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| 7. | Addressing the confounding role of joint hypermobility syndrome and gastrointestinal involvement in postural orthostatic tachycardia syndrome. |
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| 8. | Painful temporomandibular disorders are common in patients with postural orthostatic tachycardia syndrome and impact significantly upon quality of life. |
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| 9. | Mechanism of choline deficiency and membrane alteration in postural orthostatic tachycardia syndrome primary skin fibroblasts. |
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| 11. | The complexity of diagnosing postural orthostatic tachycardia syndrome: influence of the diurnal variability. |
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| 12. | [Postural orthostatic tachycardia syndrome (POTS)–pathophysiology, diagnostics, and treatment]. |
| Rek M, Kaczmarek K, Cygankiewicz I, Wranicz JK, Ptaszy?ski P. | |
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| 13. | Postural orthostatic tachycardia syndrome: a dermatologic perspective and successful treatment with losartan. |
| Landero J. | |
| J Clin Aesthet Dermatol. 2014 Aug;7(8):41-7. | |
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| 14. | Disturbances of gastrointestinal transit and autonomic functions in postural orthostatic tachycardia syndrome. |
| Loavenbruck A, Iturrino J, Singer W, Sletten DM, Low PA, Zinsmeister AR, Bharucha AE. | |
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| 15. | Postural Orthostatic Tachycardia Syndrome (POTS) – A novel member of the autoimmune family. |
| Dahan S, Tomljenovic L, Shoenfeld Y. | |
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| 16. | Stimulant medication and postural orthostatic tachycardia syndrome: a tale of two cases. |
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| 17. | Postural orthostatic tachycardia syndrome (POTS) and vitamin B12 deficiency in adolescents. |
| Öner T, Guven B, Tavli V, Mese T, Yilmazer MM, Demirpence S. | |
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| 18. | Improvement in Functioning and Psychological Distress in Adolescents With Postural Orthostatic Tachycardia Syndrome Following Interdisciplinary Treatment. |
| Bruce BK, Harrison TE, Bee SM, Luedtke CA, Porter CJ, Fischer PR, Hayes SE, Allman DA, Ale CM, Weiss KE. | |
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| 19. | Hemodynamic profile and heart rate variability in hyperadrenergic versus non-hyperadrenergic postural orthostatic tachycardia syndrome. |
| Crnošija L, Krbot Skori? M, Adamec I, Lovri? M, Junakovi? A, Mišmaš A, Mileti? V, Šprljan Alfirev R, Paveli? A, Habek M. | |
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| 20. | Autoimmunoreactive IgGs from patients with postural orthostatic tachycardia syndrome. |
| Wang XL, Chai Q, Charlesworth MC, Figueroa JJ, Low P, Shen WK, Lee HC. | |
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| 21. | Autoimmunoreactive IgGs against cardiac lipid raft-associated proteins in patients with postural orthostatic tachycardia syndrome. |
| Wang XL, Ling TY, Charlesworth MC, Figueroa JJ, Low P, Shen WK, Lee HC. | |
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| 22. | Autoimmune basis for postural tachycardia syndrome. |
| Li H, Yu X, Liles C, Khan M, Vanderlinde-Wood M, Galloway A, Zillner C, Benbrook A, Reim S, Collier D, Hill MA, Raj SR, Okamoto LE, Cunningham MW, Aston CE, Kem DC. | |
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| 23. | Diagnostic and therapeutic aspects of ?1-adrenergic receptor autoantibodies in human heart disease. |
| Bornholz B, Roggenbuck D, Jahns R, Boege F. | |
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| 24. | Invited Article: Autonomic ganglia: target and novel therapeutic tool. |
| Vernino S, Sandroni P, Singer W, Low PA. | |
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| 25. | Antibody titers predict clinical features of autoimmune autonomic ganglionopathy. |
| Gibbons CH, Freeman R. | |
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| 26. | Other autonomic neuropathies associated with ganglionic antibody. |
| Sandroni P, Low PA. | |
| Auton Neurosci. 2009 Mar 12;146(1-2):13-7. doi: 10.1016/j.autneu.2008.10.022. Epub 2008 Dec 4. Review. | |
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| 27. | The value of acetylcholine receptor antibody in children with postural tachycardia syndrome. |
| Li J, Zhang Q, Liao Y, Zhang C, Hao H, Du J. | |
| Pediatr Cardiol. 2015 Jan;36(1):165-70. doi: 10.1007/s00246-014-0981-8. Epub 2014 Aug 3. | |
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| 28. | Small fiber neuropathies. |
| Gibbons CH. | |
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| PMID: 25299289 [PubMed – indexed for MEDLINE] | |
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