Migraines and headaches affect a substantial proportion of the American population, with upwards of 15% of people suffering with migraines at any given time. Though medications and botox injections can be helpful for many, in our clinic we see a large number of individuals who’s headache are refractory to meds and botox. In today’s discussion we will cover migraine but also new daily persistent headaches, the underlying causes of these disorders, and discuss potential solutions for the headache sufferer.
Please forward us any comments here on our website or go to our Power Health Facebook page http://powerhealthreno.com/Facebook
References:
| 1. | Reduction of CD4(+)CD25(+) regulatory T-cells in migraine: Is migraine an autoimmune disorder? |
| Arumugam M, Parthasarathy V. | |
| J Neuroimmunol. 2016 Jan 15;290:54-9. doi: 10.1016/j.jneuroim.2015.11. | |
| PMID: 26711570 [PubMed – in process] | |
| Similar articles |
| 2. | Brain Aging and Disorders of the Central Nervous System: Kynurenines and Drug Metabolism. |
| Török N, Majláth Z, Fülöp F, Toldi J, Vécsei L. | |
| Curr Drug Metab. 2016;17(5):412-29. | |
| PMID: 26694727 [PubMed – in process] | |
| Similar articles |
| 3. | Antiphospholipid antibodies and migraine: a retrospective study of 428 patients with inflammatory connective tissue diseases. |
| T?n?sescu R, Nicolau A, Caraiola S, Ticmeanu M, Cojocaru IM, Fr?sineanu A, Ionescu R, Hristea A, Ene A, Anghel D, T?n?sescu R, B?icu? C. | |
| Rom J Intern Med. 2007;45(4):355-63. | |
| PMID: 18767411 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 4. | The prevalence and burden of migraine and severe headache in the United States: updated statistics from government health surveillance studies. |
| Burch RC, Loder S, Loder E, Smitherman TA. | |
| Headache. 2015 Jan;55(1):21-34. doi: 10.1111/head.12482. Review. Erratum in: Headache. 2015 Feb;55(2):356. | |
| PMID: 25600719 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 5. | Frequency of subclinical hypothyroidism in 5- to 15-year-old children with migraine headache. |
| Fallah R, Mirouliaei M, Bashardoost N, Partovee M. | |
| J Pediatr Endocrinol Metab. 2012;25(9-10):859-62. doi: 10.1515/jpem-2012-0121. | |
| PMID: 23426813 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 6. | Migraine: is it related to hormonal disturbances or stress? |
| Parashar R, Bhalla P, Rai NK, Pakhare A, Babbar R. | |
| Int J Womens Health. 2014 Oct 24;6:921-5. doi: 10.2147/IJWH.S62922. eCollection 2014. | |
| PMID: 25368535 [PubMed] Free PMC Article | |
| Similar articles |
| 7. | Anxiety and depressive symptoms and medical illness among adults with anxiety disorders. |
| Niles AN, Dour HJ, Stanton AL, Roy-Byrne PP, Stein MB, Sullivan G, Sherbourne CD, Rose RD, Craske MG. | |
| J Psychosom Res. 2015 Feb;78(2):109-15. doi: 10.1016/j.jpsychores.2014.11. | |
| PMID: 25510186 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 8. | [Clinical features of migraine and parameters of trigeminal somatosensory evoked potentials in patients with different levels of thyroid-stimulating hormone]. |
| Shestakov VV, Starikova NL. | |
| Zh Nevrol Psikhiatr Im S S Korsakova. 2010;110(12):77-81. Russian. | |
| PMID: 21311493 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 9. | Efficacy of levothyroxine in migraine headaches in children with subclinical hypothyroidism. |
| Mirouliaei M, Fallah R, Bashardoost N, Partovee M, Ordooei M. | |
| Iran J Child Neurol. 2012 Fall;6(4):23-6. | |
| PMID: 24665276 [PubMed] Free PMC Article | |
| Similar articles |
| 10. | Triggering Events and New Daily Persistent Headache: Age and Gender Differences and Insights on Pathogenesis-A Clinic-Based Study. |
| Rozen TD. | |
| Headache. 2016 Jan;56(1):164-73. doi: 10.1111/head.12707. Epub 2015 Oct 16. | |
| PMID: 26474179 [PubMed – in process] | |
| Similar articles |
| 11. | New daily persistent headache: A lack of an association with white matter abnormalities on neuroimaging. |
| Rozen TD. | |
| Cephalalgia. 2015 Oct 23. pii: 0333102415612766. [Epub ahead of print] | |
| PMID: 26498346 [PubMed – as supplied by publisher] | |
| Similar articles |
| 12. | Update on New Daily Persistent Headache. |
| Nierenburg H, Newman LC. | |
| Curr Treat Options Neurol. 2016 Jun;18(6):25. doi: 10.1007/s11940-016-0408-3. Review. | |
| PMID: 27080086 [PubMed] | |
| Similar articles |
| 13. | New daily persistent headache with a thunderclap headache onset and complete response to nimodipine (a new distinct subtype of NDPH). |
| Rozen TD, Beams JL. | |
| J Headache Pain. 2013 Dec 23;14:100. doi: 10.1186/1129-2377-14-100. | |
| PMID: 24364890 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 14. | Resolution of New Daily Persistent Headache After Osteopathic Manipulative Treatment. |
| Alexander J. | |
| J Am Osteopath Assoc. 2016 Mar 1;116(3):182-5. doi: 10.7556/jaoa.2016.035. | |
| PMID: 26927912 [PubMed – in process] | |
| Similar articles |
| 15. | New daily persistent headache: an update. |
| Rozen TD. | |
| Curr Pain Headache Rep. 2014 Jul;18(7):431. doi: 10.1007/s11916-014-0431-6. Review. | |
| PMID: 24820732 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 16. | New daily persistent headache and potential new therapeutic agents. |
| Joshi SG, Mathew PG, Markley HG. | |
| Curr Neurol Neurosci Rep. 2014 Feb;14(2):425. doi: 10.1007/s11910-013-0425-5. Review. | |
| PMID: 24402404 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 17. | New daily persistent headache. |
| Evans RW. | |
| Headache. 2012 May;52 Suppl 1:40-4. doi: 10.1111/j.1526-4610.2012. | |
| PMID: 22540206 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 18. | New daily persistent headache. |
| Rozen TD. | |
| Curr Opin Neurol. 2011 Jun;24(3):211-6. doi: 10.1097/WCO.0b013e328345c5ad. Review. | |
| PMID: 21455069 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 19. | The role of the blood-brain barrier in the development and treatment of migraine and other pain disorders. |
| DosSantos MF, Holanda-Afonso RC, Lima RL, DaSilva AF, Moura-Neto V. | |
| Front Cell Neurosci. 2014 Oct 8;8:302. doi: 10.3389/fncel.2014.00302. eCollection 2014. Review. | |
| PMID: 25339863 [PubMed] Free PMC Article | |
| Similar articles |
| 20. | Unexpected effects of peripherally administered kynurenic acid on cortical spreading depression and related blood-brain barrier permeability. |
| Oláh G, Herédi J, Menyhárt A, Czinege Z, Nagy D, Fuzik J, Kocsis K, Knapp L, Krucsó E, Gellért L, Kis Z, Farkas T, Fülöp F, Párdutz A, Tajti J, Vécsei L, Toldi J. | |
| Drug Des Devel Ther. 2013 Sep 16;7:981-7. doi: 10.2147/DDDT.S44496. eCollection 2013. | |
| PMID: 24068867 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 21. | Impact of migraine attacks on the blood-brain barrier. |
| Gao HM, Li L, Zhang KL, Chen XH, Tian SQ, Zhang ZL. | |
| Chin Med J (Engl). 2010 Sep;123(18):2559-61. | |
| PMID: 21034616 [PubMed – indexed for MEDLINE] Free Article | |
| Similar articles |
| 22. | Basic mechanisms of migraine and its acute treatment. |
| Edvinsson L, Villalón CM, MaassenVanDenBrink A. | |
| Pharmacol Ther. 2012 Dec;136(3):319-33. doi: 10.1016/j.pharmthera.2012.08. | |
| PMID: 22939884 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 23. | Does sumatriptan cross the blood-brain barrier in animals and man? |
| Tfelt-Hansen PC. | |
| J Headache Pain. 2010 Feb;11(1):5-12. doi: 10.1007/s10194-009-0170-y. Epub 2009 Dec 10. Review. | |
| PMID: 20012125 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 24. | CSD, BBB and MMP-9 elevations: animal experiments versus clinical phenomena in migraine. |
| Gupta VK. | |
| Expert Rev Neurother. 2009 Nov;9(11):1595-614. doi: 10.1586/ern.09.103. Review. | |
| PMID: 19903020 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 25. | [Mechanisms underlying migraine chronification]. |
| Shibata M. | |
| Rinsho Shinkeigaku. 2012;52(11):1012-3. Japanese. | |
| PMID: 23196500 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 26. | Spreading depression requires microglia and is decreased by their M2a polarization from environmental enrichment. |
| Pusic KM, Pusic AD, Kemme J, Kraig RP. | |
| Glia. 2014 Jul;62(7):1176-94. doi: 10.1002/glia.22672. Epub 2014 Apr 10. | |
| PMID: 24723305 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 27. | Spreading depression sends microglia on Lévy flights. |
| Grinberg YY, Milton JG, Kraig RP. | |
| PLoS One. 2011 Apr 26;6(4):e19294. doi: 10.1371/journal.pone.0019294. | |
| PMID: 21541289 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 28. | Could glial activation be a factor in migraine? |
| Bartley J. | |
| Med Hypotheses. 2009 Mar;72(3):255-7. doi: 10.1016/j.mehy.2008.09.048. Epub 2008 Nov 25. | |
| PMID: 19036526 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 29. | TNF-? and Microglial Hormetic Involvement in Neurological Health & Migraine. |
| Kraig RP, Mitchell HM, Christie-Pope B, Kunkler PE, White DM, Tang YP, Langan G. | |
| Dose Response. 2010 Feb 18;8(4):389-413. doi: 10.2203/dose-response.09-056. | |
| PMID: 21191481 [PubMed] Free PMC Article | |
| Similar articles |
| 30. | Mitochondrial dysfunction in migraine. |
| Yorns WR Jr, Hardison HH. | |
| Semin Pediatr Neurol. 2013 Sep;20(3):188-93. doi: 10.1016/j.spen.2013.09.002. | |
| PMID: 24331360 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 31. | Vitamin supplementation as possible prophylactic treatment against migraine with aura and menstrual migraine. |
| Shaik MM, Gan SH. | |
| Biomed Res Int. 2015;2015:469529. doi: 10.1155/2015/469529. Epub 2015 Feb 28. Review. | |
| PMID: 25815319 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
