Melatonin: Benefits For Sleep Just The Tip Of The Iceberg?

In today’s broadcast we will be discussing the exciting new research regarding melatonin and its ability to act as an antioxidant, and how this new research may translate to helping a number of metabolic, endocrine, and neurologic disorders. Please enjoy!
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References:
1. Melatonin based therapies for delirium and dementia.
Alagiakrishnan K.
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PMID: 27355332 [PubMed – in process] Free Article
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2. Sleep Problems in Children with Attention Deficit/Hyperactivity Disorder: Current Status of Knowledge and Appropriate Management.
Tsai MH, Hsu JF, Huang YS.
Curr Psychiatry Rep. 2016 Aug;18(8):76. doi: 10.1007/s11920-016-0711-4. Review.
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3. Salivary melatonin and cortisol and occupational injuries among Italian hospital workers.
Valent F, Mariuz M, Liva G, Verri S, Arlandini S, Vivoli R.
Neurol Sci. 2016 Jun 15. [Epub ahead of print]
PMID: 27307287 [PubMed – as supplied by publisher]
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4. Melatonin Reduces Cataract Formation and Aldose Reductase Activity in Lenses of Streptozotocin-induced Diabetic Rat.
Khorsand M Ms, Akmali M PhD, Sharzad S Md, Beheshtitabar M PhD.
Iran J Med Sci. 2016 Jul;41(4):305-313.
PMID: 27365552 [PubMed – as supplied by publisher] Free PMC Article
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5. Melatonin reduces endoplasmic reticulum stress and autophagy in liver of leptin-deficient mice.
de Luxán-Delgado B, Potes Y, Rubio-González A, Caballero B, Solano JJ, Fernández-Fernández M, Bermúdez M, Rodrigues Moreira Guimarães M, Vega-Naredo I, Boga JA, Coto-Montes A.
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6. Nutraceuticals with clinically detectable blood pressure lowering effect: a review of available randomized clinical trials and their meta-analyses.
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Br J Clin Pharmacol. 2016 Feb 6. doi: 10.1111/bcp.12902. [Epub ahead of print]
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7. Effect of myo-inositol and melatonin versus myo-inositol, in a randomized controlled trial, for improving in vitro fertilization of patients with polycystic ovarian syndrome.
Pacchiarotti A, Carlomagno G, Antonini G, Pacchiarotti A.
Gynecol Endocrinol. 2016;32(1):69-73. doi: 10.3109/09513590.2015.1101444. Epub 2015 Oct 28.
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8. Melatonin for Spinal Cord Injury in Animal Models: A Systematic Review and Network Meta-Analysis.
Yang L, Yao M, Lan Y, Mo W, Sun YL, Wang J, Wang YJ, Cui XJ.
J Neurotrauma. 2016 Feb 1;33(3):290-300. doi: 10.1089/neu.2015.4038. Epub 2016 Jan 7.
PMID: 26414869 [PubMed – in process]
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9. Pharmacokinetics of high-dose intravenous melatonin in humans.
Andersen LP, Werner MU, Rosenkilde MM, Fenger AQ, Petersen MC, Rosenberg J, Gögenur I.
J Clin Pharmacol. 2016 Mar;56(3):324-9. doi: 10.1002/jcph.592. Epub 2015 Sep 14.
PMID: 26184078 [PubMed – in process]
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10. Oxidative stress-induced methemoglobinemia is the silent killer during snakebite: a novel and strategic neutralization by melatonin.
Sharma RD, Katkar GD, Sundaram MS, Paul M, NaveenKumar SK, Swethakumar B, Hemshekhar M, Girish KS, Kemparaju K.
J Pineal Res. 2015 Sep;59(2):240-54. doi: 10.1111/jpi.12256. Epub 2015 Jul 14.
PMID: 26103459 [PubMed – indexed for MEDLINE]
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11. Beneficial effects of melatonin on serum nitric oxide, homocysteine, and ADMA levels in fructose-fed rats.
Kantar ?, Türközkan N, Bircan FS, Pa?ao?lu ÖT.
Pharm Biol. 2015 Jul;53(7):1035-41. doi: 10.3109/13880209.2014.957782. Epub 2015 Jan 22.
PMID: 25609150 [PubMed – indexed for MEDLINE]
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12. A pilot double-blind randomised placebo-controlled dose-response trial assessing the effects of melatonin on infertility treatment (MIART): study protocol.
Fernando S, Osianlis T, Vollenhoven B, Wallace E, Rombauts L.
BMJ Open. 2014 Sep 1;4(8):e005986. doi: 10.1136/bmjopen-2014-005986.
PMID: 25180056 [PubMed – indexed for MEDLINE] Free PMC Article
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