In this broadcast on “Lyme Disease, Cutting Through the B.S.” we discuss how the paradigm needs to shift for those with chronic effects of Lyme disease. The current evidence demonstrates Lyme disease, in the chronic form, to be more of an autoimmune illness. We also discuss the immunosuppressive aspects of this disease as well as how conventional and alternative testing methods are not sensitive or specific requiring a different model for testing. Please stay tuned and enjoy this broadcast.
Dr. Rutherford has worked with thousands of patients from all over the world to help them get to the root cause of their health issues and start to feel better again naturally.
If you are interested in having a consultation with Dr. Rutherford to discuss your specific case and if he feels you would be a good candidate for his protocols please visit http://powerhealthconsult.com.
References:
| 1. | Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection. |
| Elsner RA, Hastey CJ, Olsen KJ, Baumgarth N. | |
| PLoS Pathog. 2015 Jul 2;11(7):e1004976. doi: 10.1371/journal.ppat.1004976. eCollection 2015 Jul. | |
| PMID: 26136236 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 2. | Lyme disease. |
| Nat LB, Simiti AL, Poanta LI. | |
| Rom J Intern Med. 2014 Oct-Dec;52(4):269-72. | |
| PMID: 25726630 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 3. | Cerebrospinal fluid T-regulatory cells recognize Borrelia burgdorferi NAPA in chronic Lyme borreliosis. |
| Amedei A, Codolo G, Ozolins D, Ballerini C, Biagioli T, Jaunalksne I, Zilevica A, D Elios S, De Bernard M, D’ Elios MM. | |
| Int J Immunopathol Pharmacol. 2013 Oct-Dec;26(4):907-15. | |
| PMID: 24355226 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 4. | Spitting image: tick saliva assists the causative agent of Lyme disease in evading host skin’s innate immune response. |
| Hovius JW. | |
| J Invest Dermatol. 2009 Oct;129(10):2337-9. doi: 10.1038/jid.2009.202. | |
| PMID: 19749783 [PubMed – indexed for MEDLINE] Free Article | |
| Similar articles |
| 5. | Is human granulocytic ehrlichiosis a new Lyme disease? Review and comparison of clinical, laboratory, epidemiological, and some biological features. |
| Dumler JS. | |
| Clin Infect Dis. 1997 Jul;25 Suppl 1:S43-7. Review. | |
| PMID: 9233663 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 6. | Cellular immune findings in Lyme disease. Correlation with serum IgM and disease activity. |
| Moffat CM, Sigal LH, Steere AC, Freeman DH, Dwyer JM. | |
| Am J Med. 1984 Oct;77(4):625-32. | |
| PMID: 6237576 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 7. | Cutting edge: T cell-mediated pathology in murine Lyme borreliosis. |
| McKisic MD, Redmond WL, Barthold SW. | |
| J Immunol. 2000 Jun 15;164(12):6096-9. | |
| PMID: 10843657 [PubMed – indexed for MEDLINE] Free Article | |
| Similar articles |
| 8. | ?-Glucuronidase, a Regulator of Lyme Arthritis Severity, Modulates Lysosomal Trafficking and MMP-9 Secretion in Response to Inflammatory Stimuli. |
| Bramwell KK, Mock K, Ma Y, Weis JH, Teuscher C, Weis JJ. | |
| J Immunol. 2015 Aug 15;195(4):1647-56. doi: 10.4049/jimmunol.1500212. Epub 2015 Jul 13. | |
| PMID: 26170381 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 9. | Dysregulation of CD4+CD25(high) T cells in the synovial fluid of patients with antibiotic-refractory Lyme arthritis. |
| Vudattu NK, Strle K, Steere AC, Drouin EE. | |
| Arthritis Rheum. 2013 Jun;65(6):1643-53. doi: 10.1002/art.37910. | |
| PMID: 23450683 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 10. | Cellular immune findings in Lyme disease. |
| Sigal LH, Moffat CM, Steere AC, Dwyer JM. | |
| Yale J Biol Med. 1984 Jul-Aug;57(4):595-8. | |
| PMID: 6240164 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 11. | The outer surface protein A (OspA) vaccine against Lyme disease: efficacy in the rhesus monkey. |
| Philipp MT, Lobet Y, Bohm RP Jr, Roberts ED, Dennis VA, Gu Y, Lowrie RC Jr, Desmons P, Duray PH, England JD, Hauser P, Piesman J, Xu K. | |
| Vaccine. 1997 Dec;15(17-18):1872-87. | |
| PMID: 9413097 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 12. | Lyme disease: a rigorous review of diagnostic criteria and treatment. |
| Borchers AT, Keen CL, Huntley AC, Gershwin ME. | |
| J Autoimmun. 2015 Feb;57:82-115. doi: 10.1016/j.jaut.2014.09.004. Epub 2014 Oct 16. Review. | |
| PMID: 25451629 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 13. | [Lyme disease: how widespread is the problem?]. |
| van der Horst HE. | |
| Ned Tijdschr Geneeskd. 2014;158:A8175. Dutch. | |
| PMID: 25248741 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 14. | [Combatting Lyme disease]. |
| Hovius JW, Sprong H. | |
| Ned Tijdschr Geneeskd. 2014;158:A7986. Review. Dutch. | |
| PMID: 25248736 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 15. | Long-term Assessment of Post-Treatment Symptoms in Patients With Culture-Confirmed Early Lyme Disease. |
| Weitzner E, McKenna D, Nowakowski J, Scavarda C, Dornbush R, Bittker S, Cooper D, Nadelman RB, Visintainer P, Schwartz I, Wormser GP. | |
| Clin Infect Dis. 2015 Dec 15;61(12):1800-6. doi: 10.1093/cid/civ735. Epub 2015 Sep 18. | |
| PMID: 26385994 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 16. | Immunogenetic Markers Definition in Latvian Patients with Lyme Borreliosis and Lyme Neuroborreliosis. |
| Kovalchuka L, Cvetkova S, Trofimova J, Eglite J, Gintere S, Lucenko I, Oczko-Grzesik B, Viksna L, Krumina A. | |
| Int J Environ Res Public Health. 2016 Dec 1;13(12). pii: E1194. | |
| PMID: 27916969 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 17. | The Lyme disease vaccine–a public health perspective. |
| Shen AK, Mead PS, Beard CB. | |
| Clin Infect Dis. 2011 Feb;52 Suppl 3:s247-52. doi: 10.1093/cid/ciq115. Review. | |
| PMID: 21217171 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 18. | A lack of correlation between the incidence of lyme disease and deaths due to Alzheimer’s disease. |
| O’Day DH, Catalano A. | |
| J Alzheimers Dis. 2014;42(1):115-8. doi: 10.3233/JAD-140552. | |
| PMID: 24840565 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 19. | Nervous system lyme disease: is there a controversy? |
| Halperin JJ. | |
| Semin Neurol. 2011 Jul;31(3):317-24. doi: 10.1055/s-0031-1287652. Epub 2011 Sep 30. Review. | |
| PMID: 21964848 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 20. | Borrelia burgdorferi persists in the brain in chronic lyme neuroborreliosis and may be associated with Alzheimer disease. |
| Miklossy J, Khalili K, Gern L, Ericson RL, Darekar P, Bolle L, Hurlimann J, Paster BJ. | |
| J Alzheimers Dis. 2004 Dec;6(6):639-49; discussion 673-81. | |
| PMID: 15665404 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 21. | Plaques of Alzheimer’s disease originate from cysts of Borrelia burgdorferi, the Lyme disease spirochete. |
| MacDonald AB. | |
| Med Hypotheses. 2006;67(3):592-600. Epub 2006 May 3. | |
| PMID: 16675154 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 22. | Alzheimer’s disease Braak Stage progressions: reexamined and redefined as Borrelia infection transmission through neural circuits. |
| MacDonald AB. | |
| Med Hypotheses. 2007;68(5):1059-64. Epub 2006 Nov 17. | |
| PMID: 17113237 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 23. | Transfection “Junk” DNA – a link to the pathogenesis of Alzheimer’s disease? |
| MacDonald AB. | |
| Med Hypotheses. 2006;66(6):1140-1. Epub 2006 Feb 14. | |
| PMID: 16481123 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 24. | Concurrent neocortical borreliosis and Alzheimer’s disease. |
| MacDonald AB, Miranda JM. | |
| Hum Pathol. 1987 Jul;18(7):759-61. | |
| PMID: 3297997 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 25. | A life cycle for Borrelia spirochetes? |
| MacDonald AB. | |
| Med Hypotheses. 2006;67(4):810-8. Epub 2006 May 22. | |
| PMID: 16716532 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 26. | Alzheimer’s neuroborreliosis with trans-synaptic spread of infection and neurofibrillary tangles derived from intraneuronal spirochetes. |
| MacDonald AB. | |
| Med Hypotheses. 2007;68(4):822-5. Epub 2006 Oct 20. | |
| PMID: 17055667 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 27. | Spirochetal cyst forms in neurodegenerative disorders,…hiding in plain sight. |
| MacDonald AB. | |
| Med Hypotheses. 2006;67(4):819-32. Epub 2006 Jul 7. | |
| PMID: 16828236 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 28. | Use of an autologous antigen in the serologic testing of patients with erythema migrans of Lyme disease. |
| Berger BW, MacDonald AB, Benach JL. | |
| J Am Acad Dermatol. 1988 Jun;18(6):1243-6. | |
| PMID: 3290287 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 29. | Interstitial cystitis and Borrelia burgdorferi. |
| Schwan TG, MacDonald AB. | |
| Ann Intern Med. 1989 Sep 15;111(6):537. No abstract available. | |
| PMID: 2774376 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 30. | Stillbirth following maternal Lyme disease. |
| MacDonald AB, Benach JL, Burgdorfer W. | |
| N Y State J Med. 1987 Nov;87(11):615-6. No abstract available. | |
| PMID: 3480464 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 31. | Temporal arteritis associated with Borrelia infection. A case report. |
| Pizzarello LD, MacDonald AB, Semlear R, DiLeo F, Berger B. | |
| J Clin Neuroophthalmol. 1989 Mar;9(1):3-6. | |
| PMID: 2522942 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 32. | Giant cell arteritis and Borrelia infection. |
| MacDonald AB. | |
| J Clin Neuroophthalmol. 1987 Sep;7(3):180-1. No abstract available. | |
| PMID: 2958514 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 33. | Lyme disease. A neuro-ophthalmologic view. |
| MacDonald AB. | |
| J Clin Neuroophthalmol. 1987 Dec;7(4):185-90. Review. | |
| PMID: 2963023 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 34. | Gestational Lyme borreliosis. Implications for the fetus. |
| MacDonald AB. | |
| Rheum Dis Clin North Am. 1989 Nov;15(4):657-77. Review. | |
| PMID: 2685924 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 35. | Borrelia burgdorferi tissue morphologies and imaging methodologies. |
| MacDonald AB. | |
| Eur J Clin Microbiol Infect Dis. 2013 Aug;32(8):1077-82. doi: 10.1007/s10096-013-1853-5. Epub 2013 Mar 12. | |
| PMID: 23479042 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 36. | No evidence for contamination of Borrelia blood cultures: a review of facts. |
| MacDonald AB. | |
| J Clin Microbiol. 2014 May;52(5):1803. doi: 10.1128/JCM.02275-13. No abstract available. | |
| PMID: 24744404 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 37. | Characterization of biofilm formation by Borrelia burgdorferi in vitro. |
| Sapi E, Bastian SL, Mpoy CM, Scott S, Rattelle A, Pabbati N, Poruri A, Burugu D, Theophilus PA, Pham TV, Datar A, Dhaliwal NK, MacDonald A, Rossi MJ, Sinha SK, Luecke DF. | |
| PLoS One. 2012;7(10):e48277. doi: 10.1371/journal.pone.0048277. Epub 2012 Oct 24. | |
| PMID: 23110225 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 38. | Evidence of In Vivo Existence of Borrelia Biofilm in Borrelial Lymphocytomas. |
| Sapi E, Balasubramanian K, Poruri A, Maghsoudlou JS, Socarras KM, Timmaraju AV, Filush KR, Gupta K, Shaikh S, Theophilus PA, Luecke DF, MacDonald A, Zelger B. | |
| Eur J Microbiol Immunol (Bp). 2016 Feb 9;6(1):9-24. doi: 10.1556/1886.2015.00049. eCollection 2016 Mar. | |
| PMID: 27141311 [PubMed] Free PMC Article | |
| Similar articles |
| 39. | Clinical implications of delayed growth of the Lyme borreliosis spirochete, Borrelia burgdorferi. |
| MacDonald AB, Berger BW, Schwan TG. | |
| Acta Trop. 1990 Dec;48(2):89-94. | |
| PMID: 1980573 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 40. | Human fetal borreliosis, toxemia of pregnancy, and fetal death. |
| MacDonald AB. | |
| Zentralbl Bakteriol Mikrobiol Hyg A. 1986 Dec;263(1-2):189-200. No abstract available. | |
| PMID: 3554838 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 41. | Acute postnatal exposure to di(2-ethylhexyl) phthalate adversely impacts hippocampal development in the male rat. |
| Smith CA, Macdonald A, Holahan MR. | |
| Neuroscience. 2011 Oct 13;193:100-8. doi: 10.1016/j.neuroscience.2011. | |
| PMID: 21782900 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 42. | Borrelia in the brains of patients dying with dementia. |
| MacDonald AB. | |
| JAMA. 1986 Oct 24-31;256(16):2195-6. No abstract available. | |
| PMID: 3761515 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 43. | Impact of Wildfire Emissions on Chloride and Bromide Depletion in Marine Aerosol Particles. |
| Braun RA, Dadashazar H, MacDonald AB, Aldhaif AM, Maudlin LC, Crosbie E, Aghdam MA, Hossein Mardi A, Sorooshian A. | |
| Environ Sci Technol. 2017 Aug 15;51(16):9013-9021. doi: 10.1021/acs.est.7b02039. Epub 2017 Jul 27. | |
| PMID: 28700243 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 44. | Nutrition and shiftwork: evaluation of new paramedics’ knowledge and attitudes. |
| Macdonald AB, Rossiter MD, Jensen JL. | |
| Can J Diet Pract Res. 2013 Winter;74(4):198-201. | |
| PMID: 24472169 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 45. | Development and psychometric evaluation of a brief version of the hyperventilation questionnaire: the HVQ-B. |
| Sabourin BC, Stewart SH, Watt MC, Macdonald AB. | |
| Cogn Behav Ther. 2013;42(3):193-202. doi: 10.1080/16506073.2012.756059. Epub 2013 May 22. | |
| PMID: 23697597 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 46. | Acute and general medicine on opposite sides of the world. |
| MacDonald AB. | |
| Acute Med. 2011;10(2):67-8. No abstract available. | |
| PMID: 22041603 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 47. | What does the future hold for general medicine? |
| Jenkins PF, Thompson CH, MacDonald AB. | |
| Med J Aust. 2011 Jul 4;195(1):49-50. | |
| PMID: 21728946 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 48. | Molecular cloning, ontogeny and tissue distribution of zebrafish (Danio rerio) prohormone convertases: pcsk1 and pcsk2. |
| Morash MG, MacDonald AB, Croll RP, Anini Y. | |
| Gen Comp Endocrinol. 2009 Jun;162(2):179-87. doi: 10.1016/j.ygcen.2009.03.013. Epub 2009 Mar 28. | |
| PMID: 19332069 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 49. | The roles of alcohol and alcohol expectancy in the dampening of responses to hyperventilation among high anxiety sensitive young adults. |
| MacDonald AB, Stewart SH, Hutson R, Rhyno E, Loughlin HL. | |
| Addict Behav. 2001 Nov-Dec;26(6):841-67. | |
| PMID: 11768548 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 50. | Effects of alcohol on the response to hyperventilation of participants high and low in anxiety sensitivity. |
| MacDonald AB, Baker JM, Stewart SH, Skinner M. | |
| Alcohol Clin Exp Res. 2000 Nov;24(11):1656-65. | |
| PMID: 11104113 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 51. | Biochemical and functional antigenic mimicry by a polyclonal anti-idiotypic antibody for chlamydial exoglycolipid antigen. |
| An LL, Hudson AP, Prendergast RA, O’Brien TP, Stuart ES, Whittum-Hudson JA, MacDonald AB. | |
| Pathobiology. 1997;65(5):229-40. Erratum in: Pathobiology 1998;66(1):48. | |
| PMID: 9459493 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 52. | Oral immunization with an anti-idiotypic antibody to the exoglycolipid antigen protects against experimental Chlamydia trachomatis infection. |
| Whittum-Hudson JA, An LL, Saltzman WM, Prendergast RA, MacDonald AB. | |
| Nat Med. 1996 Oct;2(10):1116-21. | |
| PMID: 8837610 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 53. | The rightward gas vesicle operon in Halobacterium plasmid pNRC100: identification of the gvpA and gvpC gene products by use of antibody probes and genetic analysis of the region downstream of gvpC. |
| Halladay JT, Jones JG, Lin F, MacDonald AB, DasSarma S. | |
| J Bacteriol. 1993 Feb;175(3):684-92. | |
| PMID: 8423144 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 54. | Examination of chlamydial glycolipid with monoclonal antibodies: cellular distribution and epitope binding. |
| Stuart ES, Wyrick PB, Choong J, Stoler SB, MacDonald AB. | |
| Immunology. 1991 Dec;74(4):740-7. | |
| PMID: 1723717 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 55. | Some characteristics of a secreted chlamydial antigen recognized by IgG from C. trachomatis patient sera. |
| Stuart ES, Macdonald AB. | |
| Immunology. 1989 Dec;68(4):469-73. | |
| PMID: 2606506 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 56. | Anti-idiotypic antibodies that protect cells against the action of diphtheria toxin. |
| Rolf JM, Gaudin HM, Tirrell SM, MacDonald AB, Eidels L. | |
| Proc Natl Acad Sci U S A. 1989 Mar;86(6):2036-9. | |
| PMID: 2467297 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 57. | Characterization of an antigen secreted by Chlamydia-infected cell culture. |
| Stuart ES, Tirrell SM, MacDonald AB. | |
| Immunology. 1987 Aug;61(4):527-33. | |
| PMID: 3443454 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 58. | Oral immunization against chlamydial eye infection. |
| Taylor HR, Young E, MacDonald AB, Schachter J, Prendergast RA. | |
| Invest Ophthalmol Vis Sci. 1987 Feb;28(2):249-58. | |
| PMID: 8591904 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 59. | Antigens of Chlamydia trachomatis. |
| MacDonald AB. | |
| Rev Infect Dis. 1985 Nov-Dec;7(6):731-6. | |
| PMID: 2999944 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 60. | Nonvariant antigens limited to bloodstream forms of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. |
| Beat DA, Stanley HA, Choroma?ski L, MacDonald AB, Honigberg BM. | |
| J Protozool. 1984 Nov;31(4):541-8. | |
| PMID: 6439856 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 61. | A case of crystal formation in bone marrow. |
| Carter KJ, Jones JD, Mandel NS, Mandel GS, MacDonald AB. | |
| Clin Chem. 1984 Jul;30(7):1267-8. No abstract available. | |
| PMID: 6733919 [PubMed – indexed for MEDLINE] Free Article | |
| Similar articles |
| 62. | Immune response of owl monkeys to topical vaccination with irradiated Chlamydia trachomatis. |
| MacDonald AB, McComb D, Howard L. | |
| J Infect Dis. 1984 Mar;149(3):439-42. | |
| PMID: 6715899 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 63. | Inhibition of cholesterol side chain cleavage by active site directed antibody to corpus luteum cytochrome P-450. |
| Kashiwagi K, MacDonald AB, Salhanick HA. | |
| J Biol Chem. 1982 Mar 10;257(5):2212-7. | |
| PMID: 6895894 [PubMed – indexed for MEDLINE] Free Article | |
| Similar articles |
| 64. | The conversion of an enhancing factor to a suppressor factor by the formation of an aggregate molecule. |
| Mulcahy HL, Rubin AS, MacDonald AB. | |
| Immunology. 1981 Jan;42(1):37-43. | |
| PMID: 7007220 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 65. | Purification and properties of a factor from leukaemic T cells which non-specifically enhances the antibody response. |
| Mulcahy HL, Rubin AS, MacDonald AB. | |
| Immunology. 1981 Jan;42(1):25-35. | |
| PMID: 7007219 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 66. | Isolation and purification of a type-specific antigen from Chlamydia trachomatis propagated in cell culture utilizing molecular shift chromatography. |
| Hourihan JT, Rota TR, MacDonald AB. | |
| J Immunol. 1980 May;124(5):2399-404. | |
| PMID: 6154102 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 67. | Changes in immunoferritin labeling of Rickettsia tsutsugamushi after serial cultivation in 60Co-irradiated BHK cells. |
| Rikihisa Y, Rota T, Lee TH, MacDonald AB, Ito S. | |
| Infect Immun. 1979 Nov;26(2):638-50. | |
| PMID: 121111 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 68. | Isolation of a type-specific antigen from Chlamydia trachomatis by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. |
| Sacks DL, MacDonald AB. | |
| J Immunol. 1979 Jan;122(1):136-9. | |
| PMID: 84016 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 69. | Cell-mediated immune responses in owl monkeys (Aotus trivirgatus) with trachoma to soluble antigens of Chlamydia trachomatis. |
| Sacks DL, Todd WJ, Macdonald AB. | |
| Clin Exp Immunol. 1978 Jul;33(1):57-64. | |
| PMID: 101327 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 70. | Separation and partial characterization of a type-specific antigen from Chlamydia trachomatis. |
| Sacks DL, Rota TR, MacDonald AB. | |
| J Immunol. 1978 Jul;121(1):204-8. | |
| PMID: 78941 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 71. | Isolation and partial characterization of an antibody enhancing factor from leukaemic owl monkey cell cultures. |
| MacDonald AB, Fraser CE, Rubin AS. | |
| Immunology. 1978 Jan;34(1):137-47. | |
| PMID: 342395 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 72. | Neutralization of tetanus toxin by human and rabbit immunoglobulin classes and subunits. |
| Ourth DD, MacDonald AB. | |
| Immunology. 1977 Dec;33(6):807-15. | |
| PMID: 590997 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 73. | Partial characterization of an immunoenhancing factor from allogeneic human lymphocyte cell lines. |
| Rubin AS, Macdonald AB. | |
| Immunology. 1976 Jan;30(1):69-81. | |
| PMID: 765266 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 74. | Immunity to chlamydial infections of the eye. IV. Immunity in owl monkeys to reinfection with trachoma. |
| Fraser CE, McComb DE, Murray ES, MacDonald AB. | |
| Arch Ophthalmol. 1975 Jul;93(7):518-21. | |
| PMID: 166634 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 75. | An indirect immunofluorescent test for human antibodies to tetanus toxoid using an insoluble toxoid as antigen. |
| Ourth DD, Murray ES, MacDonald AB, Spielman JM. | |
| Clin Exp Immunol. 1975 Mar;19(3):571-7. | |
| PMID: 1106916 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 76. | The role of immunoglobulin in the neutralization of trachoma infectivity. |
| Barenfanger J, MacDonald AB. | |
| J Immunol. 1974 Nov;113(5):1607-17. No abstract available. | |
| PMID: 4214333 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 77. | Specific heterologous enhancement of immune responses. VI. Partial purification of a nonspecific enhancing factor from supernates of allogeneically stimulated human lymphocyte cell lines. |
| Rubin AS, MacDonald AB, Coons AH. | |
| J Exp Med. 1974 Feb 1;139(2):439-44. | |
| PMID: 4855755 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 78. | Specific heterologous enhancement of immune responses. V. Isolation of a soluble enhancing factor from supernatants of specifically stimulated and allogeneically induced lymphoid cells. |
| Rubin AS, MacDonald AB, Coons AH. | |
| J Immunol. 1973 Nov;111(5):1314-25. No abstract available. | |
| PMID: 4583072 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 79. | Immunity to chlamydial infections of the eye. 3. Presence and duration of delayed hypersensitivity to guinea pig inclusion conjuctivitis. |
| Watson RR, MacDonald AB, Murray ES, Modabber FZ. | |
| J Immunol. 1973 Aug;111(2):618-23. No abstract available. | |
| PMID: 4736938 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 80. | Immunity to chlamydial infections of the eye. I. The role of circulatory and secretory antibodies in resistance to reinfection with guinea pig inclusion conjunctivitis. |
| Murray ES, Charbonnet LT, MacDonald AB. | |
| J Immunol. 1973 Jun;110(6):1518-25. No abstract available. | |
| PMID: 4576503 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 81. | Immunity to chlamydial infections of the eye. VI. Homologous neutralization of trachoma infectivity for the owl monkey conjuctivae by eye secretions from humans with trachoma. |
| Nichols RL, Oertley RE, Fraser EC, MacDonald AB, McComb DE. | |
| J Infect Dis. 1973 Apr;127(4):429-32. No abstract available. | |
| PMID: 4632880 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 82. | Quantitative investigations of idiotypic antibodies. 3. Persistence and variations of idiotypic specificities during the course of immunization. |
| MacDonald AB, Nisonoff A. | |
| J Exp Med. 1970 Mar 1;131(3):583-601. | |
| PMID: 5413330 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 83. | Quantitative investigations of idiotypic antibodies. II. Nonprecipitating antibodies. |
| Hopper JE, MacDonald AB, Nisonoff A. | |
| J Exp Med. 1970 Jan 1;131(1):41-56. | |
| PMID: 5308065 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 84. | Quantitative studies of idiotypic antibodies. |
| Nisonoff A, Macdonald AB, Hopper JE, Daugharty H. | |
| Fed Proc. 1970 Jan-Feb;29(1):72-7. No abstract available. | |
| PMID: 4983815 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 85. | Quantitative investigations of idiotypic antibodies. I. Analysis of precipitating antibody populations. |
| Daugharty H, Hopper JE, MacDonald AB, Nisonoff A. | |
| J Exp Med. 1969 Nov 1;130(5):1047-62. | |
| PMID: 5347693 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 86. | Purification and properties of a nucleoside triphosphate pyrophosphohydrolase from red cells of the rabbit. |
| Chern CJ, MacDonald AB, Morris AJ. | |
| J Biol Chem. 1969 Oct 25;244(20):5489-95. No abstract available. | |
| PMID: 4310599 [PubMed – indexed for MEDLINE] Free Article | |
| Similar articles |
| 87. | Biosynthesis of antibody molecules with similar properties during prolonged immunization. |
| MacDonald AB, Alescio L, Nisonoff A. | |
| Biochemistry. 1969 Jul;8(7):3109-14. No abstract available. | |
| PMID: 5808353 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 88. | Rehabilitation, the industrial and social work of a leper colony. |
| MacDONALD AB. | |
| Lepr Rev. 1948 Apr;19(2):45-55. No abstract available. | |
| PMID: 18871564 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 89. | Nervous system Lyme disease. |
| Halperin JJ. | |
| Handb Clin Neurol. 2014;121:1473-83. doi: 10.1016/B978-0-7020-4088-7. | |
| PMID: 24365431 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 90. | Lyme disease: diagnostic issues and controversies. |
| Aguero-Rosenfeld ME, Wormser GP. | |
| Expert Rev Mol Diagn. 2015 Jan;15(1):1-4. doi: 10.1586/14737159.2015.989837. Epub 2014 Dec 8. Review. | |
| PMID: 25482091 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 91. | Lyme disease: aetiopathogenesis, factors for disease development and control. |
| Kean IR, Irvine KL. | |
| Inflammopharmacology. 2013 Apr;21(2):101-11. doi: 10.1007/s10787-012-0156-2. Epub 2012 Oct 31. Review. | |
| PMID: 23111553 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 92. | Association of immune response to endothelial cell growth factor with early disseminated and late manifestations of Lyme disease but not posttreatment Lyme disease syndrome. |
| Tang KS, Klempner MS, Wormser GP, Marques AR, Alaedini A. | |
| Clin Infect Dis. 2015 Dec 1;61(11):1703-6. doi: 10.1093/cid/civ638. Epub 2015 Jul 28. | |
| PMID: 26219695 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 93. | Lyme disease: recent advances and perspectives. |
| Petnicki-Ocwieja T, Brissette CA. | |
| Front Cell Infect Microbiol. 2015 Apr 1;5:27. doi: 10.3389/fcimb.2015.00027. eCollection 2015. No abstract available. | |
| PMID: 25883907 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 94. | Advice varies for suspected Lyme disease. |
| Eggertson L. | |
| CMAJ. 2014 Sep 2;186(12):899-900. doi: 10.1503/cmaj.109-4850. Epub 2014 Jul 28. No abstract available. | |
| PMID: 25070984 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 95. | Chronic Lyme disease: fact or fiction? |
| Sordet C. | |
| Joint Bone Spine. 2014 Mar;81(2):110-1. doi: 10.1016/j.jbspin.2013.12.003. Epub 2014 Feb 24. No abstract available. | |
| PMID: 24582003 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 96. | Diagnosis and management of Lyme disease. |
| Wright WF, Riedel DJ, Talwani R, Gilliam BL. | |
| Am Fam Physician. 2012 Jun 1;85(11):1086-93. Review. | |
| PMID: 22962880 [PubMed – indexed for MEDLINE] Free Article | |
| Similar articles |
| 97. | Natural IgM prevents autoimmunity by enforcing B cell central tolerance induction. |
| Nguyen TT, Elsner RA, Baumgarth N. | |
| J Immunol. 2015 Feb 15;194(4):1489-502. doi: 10.4049/jimmunol.1401880. Epub 2015 Jan 16. | |
| PMID: 25595791 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 98. | CD4+ T cells promote antibody production but not sustained affinity maturation during Borrelia burgdorferi infection. |
| Elsner RA, Hastey CJ, Baumgarth N. | |
| Infect Immun. 2015 Jan;83(1):48-56. doi: 10.1128/IAI.02471-14. Epub 2014 Oct 13. | |
| PMID: 25312948 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 99. | Delays and diversions mark the development of B cell responses to Borrelia burgdorferi infection. |
| Hastey CJ, Elsner RA, Barthold SW, Baumgarth N. | |
| J Immunol. 2012 Jun 1;188(11):5612-22. doi: 10.4049/jimmunol.1103735. Epub 2012 Apr 30. | |
| PMID: 22547698 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 100. | Lymphoadenopathy during lyme borreliosis is caused by spirochete migration-induced specific B cell activation. |
| Tunev SS, Hastey CJ, Hodzic E, Feng S, Barthold SW, Baumgarth N. | |
| PLoS Pathog. 2011 May;7(5):e1002066. doi: 10.1371/journal.ppat.1002066. Epub 2011 May 26. | |
| PMID: 21637808 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 101. | Lyme disease: neurology, neurobiology, and behavior. |
| Halperin JJ. | |
| Clin Infect Dis. 2014 May;58(9):1267-72. doi: 10.1093/cid/ciu106. Epub 2014 Feb 25. | |
| PMID: 24571864 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 102. | Posttreatment Lyme disease syndrome. |
| Aucott JN. | |
| Infect Dis Clin North Am. 2015 Jun;29(2):309-23. doi: 10.1016/j.idc.2015.02.012. Review. | |
| PMID: 25999226 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 103. | Long-Term Assessment of Fibromyalgia in Patients with Culture-Confirmed Lyme Disease. |
| Wormser GP, Weitzner E, McKenna D, Nadelman RB, Scavarda C, Farber S, Prakash P, Ash J, Nowakowski J. | |
| Arthritis Rheumatol. 2014 Dec 2. doi: 10.1002/art.38972. [Epub ahead of print] | |
| PMID: 25470117 [PubMed – as supplied by publisher] Free Article | |
| Similar articles |
| 104. | Characteristics of seroconversion and implications for diagnosis of post-treatment Lyme disease syndrome: acute and convalescent serology among a prospective cohort of early Lyme disease patients. |
| Rebman AW, Crowder LA, Kirkpatrick A, Aucott JN. | |
| Clin Rheumatol. 2015 Mar;34(3):585-9. doi: 10.1007/s10067-014-2706-z. Epub 2014 Jun 13. | |
| PMID: 24924604 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 105. | Development of a foundation for a case definition of post-treatment Lyme disease syndrome. |
| Aucott JN, Crowder LA, Kortte KB. | |
| Int J Infect Dis. 2013 Jun;17(6):e443-9. doi: 10.1016/j.ijid.2013.01.008. Epub 2013 Feb 23. | |
| PMID: 23462300 [PubMed – indexed for MEDLINE] Free Article | |
| Similar articles |
| 106. | CCL19 as a Chemokine Risk Factor for Posttreatment Lyme Disease Syndrome: a Prospective Clinical Cohort Study. |
| Aucott JN, Soloski MJ, Rebman AW, Crowder LA, Lahey LJ, Wagner CA, Robinson WH, Bechtold KT. | |
| Clin Vaccine Immunol. 2016 Sep 6;23(9):757-66. doi: 10.1128/CVI.00071-16. Print 2016 Sep. | |
| PMID: 27358211 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 107. | Post-treatment Lyme disease syndrome symptomatology and the impact on life functioning: is there something here? |
| Aucott JN, Rebman AW, Crowder LA, Kortte KB. | |
| Qual Life Res. 2013 Feb;22(1):75-84. | |
| PMID: 22294245 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 108. | Lyme disease and post-treatment Lyme disease syndrome: the neglected disease in our own backyard. |
| Crowder LA, Yedlin VA, Weinstein ER, Kortte KB, Aucott JN. | |
| Public Health. 2014 Sep;128(9):784-91. doi: 10.1016/j.puhe.2014.06.016. Epub 2014 Sep 9. | |
| PMID: 25213101 [PubMed – indexed for MEDLINE] | |
| Similar articles |
| 109. | Probable late lyme disease: a variant manifestation of untreated Borrelia burgdorferi infection. |
| Aucott JN, Seifter A, Rebman AW. | |
| BMC Infect Dis. 2012 Aug 1;12:173. | |
| PMID: 22853630 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 110. | Direct molecular detection and genotyping of Borrelia burgdorferi from whole blood of patients with early Lyme disease. |
| Eshoo MW, Crowder CC, Rebman AW, Rounds MA, Matthews HE, Picuri JM, Soloski MJ, Ecker DJ, Schutzer SE, Aucott JN. | |
| PLoS One. 2012;7(5):e36825. doi: 10.1371/journal.pone.0036825. Epub 2012 May 8. | |
| PMID: 22590620 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
| 111. | Development of a Multiantigen Panel for Improved Detection of Borrelia burgdorferi Infection in Early Lyme Disease. |
| Lahey LJ, Panas MW, Mao R, Delanoy M, Flanagan JJ, Binder SR, Rebman AW, Montoya JG, Soloski MJ, Steere AC, Dattwyler RJ, Arnaboldi PM, Aucott JN, Robinson WH. | |
| J Clin Microbiol. 2015 Dec;53(12):3834-41. doi: 10.1128/JCM.02111-15. Epub 2015 Oct 7. | |
| PMID: 26447113 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Similar articles |
