Today we will be discussing new scientific articles explaining the relationship between alterations in gut bacteria and the development of Eczema (Atopic Dermatitis). While we are aware that Eczema can be a multifactorial illness that is sometimes triggered by environmental sensitivities, the newest data is suggesting that these hyperactive immune responses are secondary at least in part due to inflammation at the gastrointestinal interface.
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References:
| 1. | Intestinal microbiota and allergic diseases: A systematic review. |
| Melli LC, do Carmo-Rodrigues MS, Araújo-Filho HB, Solé D, de Morais MB. | |
| Allergol Immunopathol (Madr). 2016 Mar-Apr;44(2):177-88. doi: 10.1016/j.aller.2015.01.013. Review. | |
| PMID: 25985709 [PubMed – in process] | |
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| 2. | Gut microbiome and innate immune response patterns in IgE-associated eczema. |
| West CE, Rydén P, Lundin D, Engstrand L, Tulic MK, Prescott SL. | |
| Clin Exp Allergy. 2015 Sep;45(9):1419-29. doi: 10.1111/cea.12566. | |
| PMID: 25944283 [PubMed – indexed for MEDLINE] | |
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| 3. | [Skin microbiota and atopic dermatitis: toward new therapeutic options?]. |
| Lacour JP. | |
| Ann Dermatol Venereol. 2015 Jan;142 Suppl 1:S18-22. doi: 10.1016/S0151-9638(15)30003-X. French. | |
| PMID: 25749836 [PubMed – indexed for MEDLINE] | |
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| 4. | Food intolerance and mucosal inflammation. |
| Ohtsuka Y. | |
| Pediatr Int. 2015;57(1):22-9. doi: 10.1111/ped.12546. | |
| PMID: 25442377 [PubMed – in process] | |
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| 5. | Severity of atopic disease inversely correlates with intestinal microbiota diversity and butyrate-producing bacteria. |
| Nylund L, Nermes M, Isolauri E, Salminen S, de Vos WM, Satokari R. | |
| Allergy. 2015 Feb;70(2):241-4. doi: 10.1111/all.12549. | |
| PMID: 25413686 [PubMed – indexed for MEDLINE] | |
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| 6. | Treatment of atopic dermatitis eczema with a high concentration of Lactobacillus salivarius LS01 associated with an innovative gelling complex: a pilot study on adults. |
| Drago L, De Vecchi E, Toscano M, Vassena C, Altomare G, Pigatto P. | |
| J Clin Gastroenterol. 2014 Nov-Dec;48 Suppl 1:S47-51. doi: 10.1097/MCG.0000000000000249. | |
| PMID: 25291127 [PubMed – indexed for MEDLINE] | |
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| 7. | Small intestinal permeability in patients with eosinophilic oesophagitis during active phase and remission. |
| Katzka DA, Geno DM, Blair HE, Lamsam JL, Alexander JA, Camilleri M. | |
| Gut. 2015 Apr;64(4):538-43. doi: 10.1136/gutjnl-2013-305882. | |
| PMID: 24957264 [PubMed – indexed for MEDLINE] | |
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| 8. | Efficacy of Probiotic Therapy on Atopic Dermatitis in Children: A Randomized, Double-blind, Placebo-controlled Trial. |
| Yang HJ, Min TK, Lee HW, Pyun BY. | |
| Allergy Asthma Immunol Res. 2014 May;6(3):208-15. doi: 10.4168/aair.2014.6.3.208. | |
| PMID: 24843795 [PubMed] Free PMC Article | |
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| 9. | Probiotics: immunomodulatory properties in allergy and eczema. |
| Drago L, Toscano M, Pigatto PD. | |
| G Ital Dermatol Venereol. 2013 Oct;148(5):505-14. | |
| PMID: 24005144 [PubMed – indexed for MEDLINE] | |
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| 10. | [Meta-analysis of probiotics preventing allergic diseases in infants]. |
| Tang LJ, Chen J, Shen Y. | |
| Zhonghua Er Ke Za Zhi. 2012 Jul;50(7):504-9. Chinese. | |
| PMID: 22932010 [PubMed – indexed for MEDLINE] | |
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| 11. | Low diversity of the gut microbiota in infants with atopic eczema. |
| Abrahamsson TR, Jakobsson HE, Andersson AF, Björkstén B, Engstrand L, Jenmalm MC. | |
| J Allergy Clin Immunol. 2012 Feb;129(2):434-40, 440.e1-2. doi: 10.1016/j.jaci.2011.10.025. | |
| PMID: 22153774 [PubMed – indexed for MEDLINE] | |
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| 12. | Mode and place of delivery, gastrointestinal microbiota, and their influence on asthma and atopy. |
| van Nimwegen FA, Penders J, Stobberingh EE, Postma DS, Koppelman GH, Kerkhof M, Reijmerink NE, Dompeling E, van den Brandt PA, Ferreira I, Mommers M, Thijs C. | |
| J Allergy Clin Immunol. 2011 Nov;128(5):948-55.e1-3. doi: 10.1016/j.jaci.2011.07.027. | |
| PMID: 21872915 [PubMed – indexed for MEDLINE] | |
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| 13. | Any benefits of probiotics in allergic disorders? |
| Ozdemir O. | |
| Allergy Asthma Proc. 2010 Mar-Apr;31(2):103-11. doi: 10.2500/aap.2010.31.3313. Review. | |
| PMID: 20406592 [PubMed – indexed for MEDLINE] | |
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| 14. | Various effects of different probiotic strains in allergic disorders: an update from laboratory and clinical data. |
| Ozdemir O. | |
| Clin Exp Immunol. 2010 Jun;160(3):295-304. doi: 10.1111/j.1365-2249.2010. | |
| PMID: 20345982 [PubMed – indexed for MEDLINE] Free PMC Article | |
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