Fibromyalgia: What is Causing the Fatigue?

Fatigue is a central component of fibromyalgia and for patients is often one of the most confusing symptoms associated with the condition.  In today’s broadcast we will discuss underlying causes of the persistent fatigue and new research relative to this symptom complex.
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References:
1. Role for a water-soluble form of CoQ10 in female subjects affected by fibromyalgia. A preliminary study.
Di Pierro F, Rossi A, Consensi A, Giacomelli C, Bazzichi L.
Clin Exp Rheumatol. 2016 Dec 13. [Epub ahead of print]
PMID: 27974102 [PubMed – as supplied by publisher]
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2. Stress, Inflammation and Pain: A Potential Role for Monocytes in Fibromyalgia-related Symptom Severity.
Taylor AG, Fischer-White TG, Anderson JG, Adelstein KE, Murugesan M, Lewis JE, Scott MM, Gaykema RP, Goehler LE.
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3. 2016 Revisions to the 2010/2011 fibromyalgia diagnostic criteria.
Wolfe F, Clauw DJ, Fitzcharles MA, Goldenberg DL, Häuser W, Katz RL, Mease PJ, Russell AS, Russell IJ, Walitt B.
Semin Arthritis Rheum. 2016 Dec;46(3):319-329. doi: 10.1016/j.semarthrit.2016.08.012.
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4. Tiredness and fatigue during processes of illness and recovery: A qualitative study of women recovered from fibromyalgia syndrome.
Grape HE, Solbrække KN, Kirkevold M, Mengshoel AM.
Physiother Theory Pract. 2017 Jan;33(1):31-40. doi: 10.1080/09593985.2016.1247933.
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5. Gender Differences in Symptoms, Health-Related Quality of Life, Sleep Quality, Mental Health, Cognitive Performance, Pain-Cognition, and Positive Health in Spanish Fibromyalgia Individuals: The Al-Ándalus Project.
Segura-Jiménez V, Estévez-López F, Soriano-Maldonado A, Álvarez-Gallardo IC, Delgado-Fernández M, Ruiz JR, Aparicio VA.
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6. The relationship between balance and vitamin 25(OH)D in fibromyalgia patients.
Kasapo?lu Aksoy M, Altan L, Ökmen Metin B.
Mod Rheumatol. 2016 Dec 9:1-7. [Epub ahead of print]
PMID: 27846770 [PubMed – as supplied by publisher]
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7. Variations in the management of fibromyalgia by physician specialty: rheumatology versus primary care.
Able SL, Robinson RL, Kroenke K, Mease P, Williams DA, Chen Y, Wohlreich M, McCarberg BH.
Pragmat Obs Res. 2016 May 20;7:11-20.
PMID: 27799842 [Unknown status] Free PMC Article
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8. Fibromyalgia syndrome: metabolic and autophagic processes in intermittent cold stress mice.
Oezel L, Then H, Jung AL, Jabari S, Bonaterra GA, Wissniowski TT, Önel SF, Ocker M, Thieme K, Kinscherf R, Di Fazio P.
Pharmacol Res Perspect. 2016 Sep 27;4(5):e00248.
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9. A novel paradigm to evaluate conditioned pain modulation in fibromyalgia.
Schoen CJ, Ablin JN, Ichesco E, Bhavsar RJ, Kochlefl L, Harris RE, Clauw DJ, Gracely RH, Harte SE.
J Pain Res. 2016 Sep 26;9:711-719.
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10. Rumination modulates stress and other psychological processes in fibromyalgia.
Malin K, Littlejohn GO.
Eur J Rheumatol. 2015 Dec;2(4):143-148.
PMID: 27708952 [Unknown status] Free PMC Article
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11. The association between borderline personality disorder, fibromyalgia and chronic fatigue syndrome: systematic review.
Penfold S, St Denis E, Mazhar MN.
BJPsych Open. 2016 Sep 2;2(4):275-279. Review.
PMID: 27703787 [Unknown status] Free PMC Article
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12. Impact of fatigue on postural control in quiet standing in fibromyalgia.
Vaillant J, Revillet P, Sevenier AM, Juvin R.
Ann Phys Rehabil Med. 2016 Sep;59S:e124-e125. doi: 10.1016/j.rehab.2016.07.280.
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13. Distinctive personality profiles of fibromyalgia and chronic fatigue syndrome patients.
Ablin JN, Zohar AH, Zaraya-Blum R, Buskila D.
PeerJ. 2016 Sep 13;4:e2421. doi: 10.7717/peerj.2421.
PMID: 27672497 [PubMed] Free PMC Article
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14. Subjects with fibromyalgia syndrome have a reduction of balance performance.
Vaillant J, Pissety S, Martinez S, Juvin R.
Ann Phys Rehabil Med. 2016 Sep;59S:e111-e112. doi: 10.1016/j.rehab.2016.07.249.
PMID: 27676727 [PubMed – as supplied by publisher]
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15. The Inflammatory Fibromyalgia.
Metyas S, Rezk T, Arkfeld D, Leptich T.
Curr Rheumatol Rev. 2016 Sep 19. [Epub ahead of print]
PMID: 27655626 [PubMed – as supplied by publisher]
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16. Self-Regulatory Fatigue: A Missing Link in Understanding Fibromyalgia and Other Chronic MultiSymptom Illnesses.
Nes LS, Ehlers SL, Whipple MO, Vincent A.
Pain Pract. 2016 Sep 2. doi: 10.1111/papr.12480. [Epub ahead of print]
PMID: 27589266 [PubMed – as supplied by publisher]
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17. Resistance exercise improves physical fatigue in women with fibromyalgia: a randomized controlled trial.
Ericsson A, Palstam A, Larsson A, Löfgren M, Bileviciute-Ljungar I, Bjersing J, Gerdle B, Kosek E, Mannerkorpi K.
Arthritis Res Ther. 2016 Jul 30;18:176. doi: 10.1186/s13075-016-1073-3.
PMID: 27473164 [Unknown status] Free PMC Article
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