Do Statins Cause Peripheral Neuropathy?

Today we are discussing an interesting and hot topic regarding the widely used cholesterol lowering medications, termed statins, and their association with peripheral neuropathy.  In today’s broadcast we will attempt to present both sides of the argument, and what this all means to the peripheral neuropathy sufferer.  Please enjoy!
Please forward us any comments here on our website or go to our Power Health Facebook page http://powerhealthreno.com/Facebook
References:
1. Statin safety: a systematic review.
Law M, Rudnicka AR.
Am J Cardiol. 2006 Apr 17;97(8A):52C-60C. Epub 2006 Feb 3. Review.
PMID: 16581329 [PubMed – indexed for MEDLINE]
Similar articles
2. Advances in understanding drug-induced neuropathies.
Peltier AC, Russell JW.
Drug Saf. 2006;29(1):23-30. Review.
PMID: 16454532 [PubMed – indexed for MEDLINE]
Similar articles
3. Statin-associated neuromyotoxicity.
Baker SK, Tarnopolsky MA.
Timely Top Med Cardiovasc Dis. 2005 Sep 1;9:E26.
PMID: 16215630 [PubMed – in process]
Similar articles
4. Toxic neuropathy.
Umapathi T, Chaudhry V.
Curr Opin Neurol. 2005 Oct;18(5):574-80. Review.
PMID: 16155443 [PubMed – indexed for MEDLINE]
Similar articles
5. Neuronal nitric oxide synthase mediates statin-induced restoration of vasa nervorum and reversal of diabetic neuropathy.
Ii M, Nishimura H, Kusano KF, Qin G, Yoon YS, Wecker A, Asahara T, Losordo DW.
Circulation. 2005 Jul 5;112(1):93-102. Epub 2005 Jun 27.
PMID: 15983249 [PubMed – indexed for MEDLINE] Free Article
Similar articles
6. Lipid lowering drugs prescription and the risk of peripheral neuropathy: an exploratory case-control study using automated databases.
Corrao G, Zambon A, Bertù L, Botteri E, Leoni O, Contiero P.
J Epidemiol Community Health. 2004 Dec;58(12):1047-51.
PMID: 15547071 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
7. Statin-associated peripheral neuropathy: review of the literature.
Chong PH, Boskovich A, Stevkovic N, Bartt RE.
Pharmacotherapy. 2004 Sep;24(9):1194-203. Review.
PMID: 15460180 [PubMed – indexed for MEDLINE] Free Article
Similar articles
8. Disorder resembling Guillain-Barré syndrome on initiation of statin therapy.
Rajabally YA, Varakantam V, Abbott RJ.
Muscle Nerve. 2004 Nov;30(5):663-6.
PMID: 15389662 [PubMed – indexed for MEDLINE]
Similar articles
9. Looking to the future: diabetic neuropathy and effects of rosuvastatin on neurovascular function in diabetes models.
Cameron N, Cotter M, Inkster M, Nangle M.
Diabetes Res Clin Pract. 2003 Jul;61 Suppl 1:S35-9. Review.
PMID: 12880693 [PubMed – indexed for MEDLINE]
Similar articles
10. Prevention of the complications of diabetes.
Vinik AI, Vinik E.
Am J Manag Care. 2003 Mar;9(3 Suppl):S63-80; quiz S81-4. Review.
PMID: 12653455 [PubMed – indexed for MEDLINE] Free Article
Similar articles
11. Statin therapy and small fibre neuropathy: a serial electrophysiological study.
Lo YL, Leoh TH, Loh LM, Tan CE.
J Neurol Sci. 2003 Apr 15;208(1-2):105-8.
PMID: 12639733 [PubMed – indexed for MEDLINE]
Similar articles
12. Association of HMG-CoA reductase inhibitors with neuropathy.
Backes JM, Howard PA.
Ann Pharmacother. 2003 Feb;37(2):274-8. Review.
PMID: 12549960 [PubMed – indexed for MEDLINE]
Similar articles
13. Medication-induced peripheral neuropathy.
Weimer LH.
Curr Neurol Neurosci Rep. 2003 Jan;3(1):86-92. Review.
PMID: 12507417 [PubMed – indexed for MEDLINE]
Similar articles
14. Statins and risk of polyneuropathy: a case-control study.
Gaist D, Jeppesen U, Andersen M, García Rodríguez LA, Hallas J, Sindrup SH.
Neurology. 2002 May 14;58(9):1333-7.
PMID: 12011277 [PubMed – indexed for MEDLINE]
Similar articles
15. Are users of lipid-lowering drugs at increased risk of peripheral neuropathy?
Gaist D, García Rodríguez LA, Huerta C, Hallas J, Sindrup SH.
Eur J Clin Pharmacol. 2001 Mar;56(12):931-3.
PMID: 11317483 [PubMed – indexed for MEDLINE]
Similar articles
16. Statins and peripheral neuropathy.
Jeppesen U, Gaist D, Smith T, Sindrup SH.
Eur J Clin Pharmacol. 1999 Jan;54(11):835-8.
PMID: 10027656 [PubMed – indexed for MEDLINE]
Similar articles
17. Peripheral neuropathy and lipid-lowering therapy.
Ziajka PE, Wehmeier T.
South Med J. 1998 Jul;91(7):667-8. Review.
PMID: 9671841 [PubMed – indexed for MEDLINE]
Similar articles
18. Peripheral neuropathy associated with simvastatin.
Phan T, McLeod JG, Pollard JD, Peiris O, Rohan A, Halpern JP.
J Neurol Neurosurg Psychiatry. 1995 May;58(5):625-8.
PMID: 7745415 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
19. HMG-CoA reductase inhibitor therapy and peripheral neuropathy.
Jacobs MB.
Ann Intern Med. 1994 Jun 1;120(11):970. No abstract available.
PMID: 8172444 [PubMed – indexed for MEDLINE]
Similar articles

Leave a Comment

Your email address will not be published. Required fields are marked *

*

This site uses Akismet to reduce spam. Learn how your comment data is processed.