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Today we will be discussing an important and little discussed topic relative to Traumatic Brain Injury and concussion sufferers. New research is demonstrating significant hormonal disturbances in upwards of half of brain injury patients, and that these alterations in hormones can be correlated with post concussion symptoms.
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References:
| 1. | Diffuse traumatic brain injury affects chronic corticosterone function in the rat. |
| Rowe RK, Rumney BM, May HG, Permana P, Adelson PD, Harman SM, Lifshitz J, Thomas TC. | |
| Endocr Connect. 2016 Jul;5(4):152-66. doi: 10.1530/EC-16-0031. Epub 2016 Jun 17. | |
| PMID: 27317610 [PubMed] Free Article | |
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| 2. | Catecholamines and Paroxysmal Sympathetic Hyperactivity after Traumatic Brain Injury. |
| Fernandez-Ortega JF, Baguley IJ, Gates TA, Garcia-Caballero M, Quesada-Garcia JG, Prieto-Palomino MA. | |
| J Neurotrauma. 2016 Jul 8. [Epub ahead of print] | |
| PMID: 27251119 [PubMed – as supplied by publisher] | |
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| 3. | Circadian Melatonin Rhythm Following Traumatic Brain Injury. |
| Grima NA, Ponsford JL, St Hilaire MA, Mansfield D, Rajaratnam SM. | |
| Neurorehabil Neural Repair. 2016 May 23. pii: 1545968316650279. [Epub ahead of print] | |
| PMID: 27221043 [PubMed – as supplied by publisher] | |
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| 4. | Secondary Adrenal Insufficiency: Where Is It Hidden and What Does It Look Like? |
| Guaraldi F, Karamouzis I, Berardelli R, D’Angelo V, Rampino A, Zichi C, Ghigo E, Giordano R. | |
| Front Horm Res. 2016;46:159-70. doi: 10.1159/000443915. Epub 2016 May 17. | |
| PMID: 27211575 [PubMed – in process] | |
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| 5. | Isolated Adrenocorticotropic Hormone or Thyrotropin Deficiency Following Mild Traumatic Brain Injury: Three Cases with Long-Term Follow-Up. |
| Baek CO, Kim YJ, Kim JH, Park JH. | |
| Korean J Neurotrauma. 2015 Oct;11(2):139-43. doi: 10.13004/kjnt.2015.11.2.139. Epub 2015 Oct 31. | |
| PMID: 27169080 [PubMed] Free PMC Article | |
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| 6. | Circulating MicroRNAs as Potential Biomarkers for Traumatic Brain Injury-Induced Hypopituitarism. |
| Taheri S, Tanriverdi F, Zararsiz G, Elbuken G, Ulutabanca H, Karaca Z, Selcuklu A, Unluhizarci K, Tanriverdi K, Kelestimur F. | |
| J Neurotrauma. 2016 Mar 30. [Epub ahead of print] | |
| PMID: 27027233 [PubMed – as supplied by publisher] | |
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| 7. | Neuroprotection by Estrogen and Progesterone in Traumatic Brain Injury and Spinal Cord Injury. |
| Brotfain E, Gruenbaum SE, Boyko M, Kutz R, Zlotnik A, Klein M. | |
| Curr Neuropharmacol. 2016;14(6):641-53. | |
| PMID: 26955967 [PubMed – in process] | |
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| 8. | GH and Pituitary Hormone Alterations After Traumatic Brain Injury. |
| Karaca Z, Tanr?verdi F, Ünlüh?zarc? K, Kelestimur F. | |
| Prog Mol Biol Transl Sci. 2016;138:167-91. doi: 10.1016/bs.pmbts.2015.10.010. Epub 2015 Nov 4. | |
| PMID: 26940391 [PubMed – in process] | |
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| 9. | Voxel-based statistical analysis of brain metabolism in patients with growth hormone deficiency after traumatic brain injury. |
| Park KD, Lim OK, Yoo CJ, Kim YW, Lee S, Park Y, Lee JK. | |
| Brain Inj. 2016 Feb 24:1-7. [Epub ahead of print] | |
| PMID: 26910852 [PubMed – as supplied by publisher] | |
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| 10. | Chronic Exposure to Androgenic-Anabolic Steroids Exacerbates Axonal Injury and Microgliosis in the CHIMERA Mouse Model of Repetitive Concussion. |
| Namjoshi DR, Cheng WH, Carr M, Martens KM, Zareyan S, Wilkinson A, McInnes KA, Cripton PA, Wellington CL. | |
| PLoS One. 2016 Jan 19;11(1):e0146540. doi: 10.1371/journal.pone.0146540. eCollection 2016. | |
| PMID: 26784694 [PubMed – indexed for MEDLINE] Free PMC Article | |
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| 11. | Enduring changes in tonic GABAA receptor signaling in dentate granule cells after controlled cortical impact brain injury in mice. |
| Boychuk JA, Butler CR, Halmos KC, Smith BN. | |
| Exp Neurol. 2016 Mar;277:178-89. doi: 10.1016/j.expneurol.2016.01. | |
| PMID: 26772635 [PubMed – indexed for MEDLINE] | |
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| 12. | The Development of Neuroendocrine Disturbances over Time: Longitudinal Findings in Patients after Traumatic Brain Injury and Subarachnoid Hemorrhage. |
| Kopczak A, Krewer C, Schneider M, Kreitschmann-Andermahr I, Schneider HJ, Stalla GK. | |
| Int J Mol Sci. 2015 Dec 22;17(1). pii: E2. doi: 10.3390/ijms17010002. | |
| PMID: 26703585 [PubMed – in process] Free PMC Article | |
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| 13. | Pituitary and/or hypothalamic dysfunction following moderate to severe traumatic brain injury: Current perspectives. |
| Javed Z, Qamar U, Sathyapalan T. | |
| Indian J Endocrinol Metab. 2015 Nov-Dec;19(6):753-63. doi: 10.4103/2230-8210.167561. Review. | |
| PMID: 26693424 [PubMed] Free PMC Article | |
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| 14. | Post-traumatic hypopituitarism and fatigue. |
| Masel BE, Zgaljardic DJ, Forman J. | |
| Neuropsychol Rehabil. 2015 Dec 18:1-11. [Epub ahead of print] | |
| PMID: 26682872 [PubMed – as supplied by publisher] | |
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| 15. | Efficacy of Progesterone for Acute Traumatic Brain Injury: a Meta-analysis of Randomized Controlled Trials. |
| Wang Z, Shi L, Ding W, Shao F, Yu J, Zhang J. | |
| Mol Neurobiol. 2015 Dec 16. [Epub ahead of print] | |
| PMID: 26676571 [PubMed – as supplied by publisher] | |
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