Chronic Lyme Disease: Urgent Need for Better Testing

There is tremendous confusion surrounding testing for Lyme disease after the acute phase.  In today’s broadcast we will discuss some of the pitfalls with this testing, arguments why chronic Lyme disease does not exist based on the current testing model, and why a new paradigm is needed for testing patients for chronic infections with Borrelia.

Please forward us any comments here on our website or go to our Power Health Facebook page
1.Nervous system Lyme disease.
Halperin JJ.
Handb Clin Neurol. 2014;121:1473-83. doi: 10.1016/B978-0-7020-4088-7.00099-7. Review.
PMID: 24365431 [PubMed – indexed for MEDLINE]
Similar articles
2.Lyme disease: diagnostic issues and controversies.
Aguero-Rosenfeld ME, Wormser GP.
Expert Rev Mol Diagn. 2015 Jan;15(1):1-4. doi: 10.1586/14737159.2015.989837. Epub 2014 Dec 8. Review.
PMID: 25482091 [PubMed – indexed for MEDLINE]
Similar articles
3.Lyme disease: aetiopathogenesis, factors for disease development and control.
Kean IR, Irvine KL.
Inflammopharmacology. 2013 Apr;21(2):101-11. doi: 10.1007/s10787-012-0156-2. Epub 2012 Oct 31. Review.
PMID: 23111553 [PubMed – indexed for MEDLINE]
Similar articles
4.Association of immune response to endothelial cell growth factor with early disseminated and late manifestations of Lyme disease but not posttreatment Lyme disease syndrome.
Tang KS, Klempner MS, Wormser GP, Marques AR, Alaedini A.
Clin Infect Dis. 2015 Dec 1;61(11):1703-6. doi: 10.1093/cid/civ638. Epub 2015 Jul 28.
PMID: 26219695 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
5.Lyme disease: recent advances and perspectives.
Petnicki-Ocwieja T, Brissette CA.
Front Cell Infect Microbiol. 2015 Apr 1;5:27. doi: 10.3389/fcimb.2015.00027. eCollection 2015. No abstract available.
PMID: 25883907 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
6.Advice varies for suspected Lyme disease.
Eggertson L.
CMAJ. 2014 Sep 2;186(12):899-900. doi: 10.1503/cmaj.109-4850. Epub 2014 Jul 28. No abstract available.
PMID: 25070984 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
7.Chronic Lyme disease: fact or fiction?
Sordet C.
Joint Bone Spine. 2014 Mar;81(2):110-1. doi: 10.1016/j.jbspin.2013.12.003. Epub 2014 Feb 24. No abstract available.
PMID: 24582003 [PubMed – indexed for MEDLINE]
Similar articles
8.Diagnosis and management of Lyme disease.
Wright WF, Riedel DJ, Talwani R, Gilliam BL.
Am Fam Physician. 2012 Jun 1;85(11):1086-93. Review.
PMID: 22962880 [PubMed – indexed for MEDLINE] Free Article
Similar articles
9.Natural IgM prevents autoimmunity by enforcing B cell central tolerance induction.
Nguyen TT, Elsner RA, Baumgarth N.
J Immunol. 2015 Feb 15;194(4):1489-502. doi: 10.4049/jimmunol.1401880. Epub 2015 Jan 16.
PMID: 25595791 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
10.Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection.
Elsner RA, Hastey CJ, Olsen KJ, Baumgarth N.
PLoS Pathog. 2015 Jul 2;11(7):e1004976. doi: 10.1371/journal.ppat.1004976. eCollection 2015 Jul.
PMID: 26136236 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
11.CD4+ T cells promote antibody production but not sustained affinity maturation during Borrelia burgdorferi infection.
Elsner RA, Hastey CJ, Baumgarth N.
Infect Immun. 2015 Jan;83(1):48-56. doi: 10.1128/IAI.02471-14. Epub 2014 Oct 13.
PMID: 25312948 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
12.Delays and diversions mark the development of B cell responses to Borrelia burgdorferi infection.
Hastey CJ, Elsner RA, Barthold SW, Baumgarth N.
J Immunol. 2012 Jun 1;188(11):5612-22. doi: 10.4049/jimmunol.1103735. Epub 2012 Apr 30.
PMID: 22547698 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
13.Lymphoadenopathy during lyme borreliosis is caused by spirochete migration-induced specific B cell activation.
Tunev SS, Hastey CJ, Hodzic E, Feng S, Barthold SW, Baumgarth N.
PLoS Pathog. 2011 May;7(5):e1002066. doi: 10.1371/journal.ppat.1002066. Epub 2011 May 26.
PMID: 21637808 [PubMed – indexed for MEDLINE] Free PMC Article
Similar articles
14.Lyme disease: neurology, neurobiology, and behavior.
Halperin JJ.
Clin Infect Dis. 2014 May;58(9):1267-72. doi: 10.1093/cid/ciu106. Epub 2014 Feb 25.
PMID: 24571864 [PubMed – indexed for MEDLINE]
Similar articles

Leave a Comment

Your email address will not be published. Required fields are marked *