Asthma: Connections to the Microbiome

Today we will be discussing new literature demonstrating asthma sufferers to have different colonies of bacterial in the lungs than normal controls.  We will also discuss this in the context of allergic diseases and potential new therapies on the horizon.
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1.‘The Microbiome and the Pathophysiology of Asthma’.
Sullivan A, Hunt E, MacSharry J, Murphy DM.
Respir Res. 2016 Dec 5;17(1):163. Review.
PMID: 27919249 [Unknown status] Free Article
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2.Evidence of microbiota dysbiosis in chronic rhinosinusitis.
Hoggard M, Biswas K, Zoing M, Wagner Mackenzie B, Taylor MW, Douglas RG.
Int Forum Allergy Rhinol. 2016 Nov 23. doi: 10.1002/alr.21871. [Epub ahead of print]
PMID: 27879060 [PubMed – as supplied by publisher]
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3.The microbiome in asthma.
Noval Rivas M, Crother TR, Arditi M.
Curr Opin Pediatr. 2016 Dec;28(6):764-771.
PMID: 27606957 [Unknown status]
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4.The possible mechanisms of the human microbiome in allergic diseases.
Ipci K, Alt?ntoprak N, Muluk NB, Senturk M, Cingi C.
Eur Arch Otorhinolaryngol. 2016 Apr 26. [Epub ahead of print] Review.
PMID: 27115907 [PubMed – as supplied by publisher]
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5.Microbiome diversity and asthma and allergy risk.
Legatzki A, Rösler B, von Mutius E.
Curr Allergy Asthma Rep. 2014 Oct;14(10):466. doi: 10.1007/s11882-014-0466-0. Review.
PMID: 25149168 [PubMed – indexed for MEDLINE]
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6.The relationships between environmental bacterial exposure, airway bacterial colonization, and asthma.
Beigelman A, Weinstock GM, Bacharier LB.
Curr Opin Allergy Clin Immunol. 2014 Apr;14(2):137-42. doi: 10.1097/ACI.0000000000000036. Review.
PMID: 24451910 [PubMed – indexed for MEDLINE] Free PMC Article
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7.The microbiome in asthma.
Huang YJ, Boushey HA.
J Allergy Clin Immunol. 2015 Jan;135(1):25-30. doi: 10.1016/j.jaci.2014.11.011. Review.
PMID: 25567040 [PubMed – indexed for MEDLINE] Free PMC Article
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8.Microbiota in allergy and asthma and the emerging relationship with the gut microbiome.
Fujimura KE, Lynch SV.
Cell Host Microbe. 2015 May 13;17(5):592-602. doi: 10.1016/j.chom.2015.04.007. Review.
PMID: 25974301 [PubMed – indexed for MEDLINE] Free PMC Article
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9.Gut Microbiome and the Development of Food Allergy and Allergic Disease.
Prince BT, Mandel MJ, Nadeau K, Singh AM.
Pediatr Clin North Am. 2015 Dec;62(6):1479-92. doi: 10.1016/j.pcl.2015.07.007. Review.
PMID: 26456445 [PubMed – indexed for MEDLINE] Free PMC Article
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10.Far from the eyes, close to the heart: dysbiosis of gut microbiota and cardiovascular consequences.
Serino M, Blasco-Baque V, Nicolas S, Burcelin R.
Curr Cardiol Rep. 2014 Nov;16(11):540. doi: 10.1007/s11886-014-0540-1. Review.
PMID: 25303894 [PubMed – indexed for MEDLINE] Free PMC Article
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11.Influences of the microbiome on the early origins of allergic asthma.
Marsland BJ.
Ann Am Thorac Soc. 2013 Dec;10 Suppl:S165-9. doi: 10.1513/AnnalsATS.201305-118AW. Review.
PMID: 24313768 [PubMed – indexed for MEDLINE]
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12.New developments providing mechanistic insight into the impact of the microbiota on allergic disease.
McCoy KD, Köller Y.
Clin Immunol. 2015 Aug;159(2):170-6. doi: 10.1016/j.clim.2015.05.007. Review.
PMID: 25988860 [PubMed – indexed for MEDLINE] Free PMC Article
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13.Western diseases: current concepts and implications for pediatric surgery research and practice.
Bickler SW, DeMaio A.
Pediatr Surg Int. 2008 Mar;24(3):251-5. Review.
PMID: 18087704 [PubMed – indexed for MEDLINE]
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14.Tropical enteropathy protects against Western diseases in environments of poor sanitation.
Bickler SW.
Med Hypotheses. 2006;67(1):146-50.
PMID: 16545527 [PubMed – indexed for MEDLINE]
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