PHT Live – Neuroplasticity Neurological Rehabilitation for Stroke Patients, Balance Disorders, and Chronic Pain

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Today we have a great broadcast on rehabilitation for neurologic disorders. It was learned in the 1980’s that the brain is able to change. It was thought for most of the 20th century that once our brain had developed, it was not capable of growing new connections. However, the research of Dr. Kandel from Columbia University disproved this notion, and since then we have observed an explosion in research relative to the field of neuroplasticity and neurologic rehabilitation.

Attached are 30+ articles conglomerated in a short period of time (that is only mentioned as there are tens of thousands of articles on the subject), that discuss the efficacy of employing neuroplasticity based treatments for the effect of helping those with disorders such as lack of balance, pain, neuropathy, and individuals recovering from stroke. We hope you enjoy the broadcast, and we will attempt also to cover our clinical observations relative to neuroplasticity, and how they may tie in with the pro’s and con’s of this type of translational neuroscience.

1.Preliminary evidence for performance enhancement following parietal lobe stimulation in Developmental Dyscalculia.
Iuculano T, Cohen Kadosh R.
Front Hum Neurosci. 2014 Feb 7;8:38. doi: 10.3389/fnhum.2014.00038. eCollection 2014.
PMID: 24570659 [PubMed] Free PMC Article
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2.Forced arm use is superior to voluntary training for motor recovery and brain plasticity after cortical ischemia in rats.
Schneider A, Rogalewski A, Wafzig O, Kirsch F, Gretz N, Krüger C, Diederich K, Pitzer C, Laage R, Plaas C, Vogt G, Minnerup J, Schäbitz WR.
Exp Transl Stroke Med. 2014 Feb 14;6(1):3. doi: 10.1186/2040-7378-6-3.
PMID: 24528872 [PubMed] Free PMC Article
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3.Effect of oculomotor rehabilitation on vergence responsivity in mild traumatic brain injury.
Thiagarajan P, Ciuffreda KJ.
J Rehabil Res Dev. 2013;50(9):1223-40. doi: 10.1682/JRRD.2012.12.0235.
PMID: 24458963 [PubMed – in process] Free Article
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4.Innovative strength training-induced neuroplasticity and increased muscle size and strength in children with spastic cerebral palsy: An experimenter-blind case study – three-month follow-up.
Lee DR, Kim YH, Kim DA, Lee JA, Hwang PW, Lee MJ, You SH.
NeuroRehabilitation. 2014 Jan 13. [Epub ahead of print]
PMID: 24419014 [PubMed – as supplied by publisher]
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5.Induction of neuroplasticity and recovery in post-stroke aphasia by non-invasive brain stimulation.
Shah PP, Szaflarski JP, Allendorfer J, Hamilton RH.
Front Hum Neurosci. 2013 Dec 24;7:888. eCollection 2013. Review.
PMID: 24399952 [PubMed – as supplied by publisher] Free PMC Article
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6.Voluntary forced use of the impaired limb following stroke facilitates functional recovery in the rat.
Livingston-Thomas JM, McGuire EP, Doucette TA, Tasker RA.
Behav Brain Res. 2014 Mar 15;261:210-9. doi: 10.1016/j.bbr.2013.12.032. Epub 2013 Dec 31.
PMID: 24388978 [PubMed – in process]
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7.Effect of intensive functional electrical stimulation therapy on upper-limb motor recovery after stroke: case study of a patient with chronic stroke.
Kawashima N, Popovic MR, Zivanovic V.
Physiother Can. 2013 Winter;65(1):20-8. doi: 10.3138/ptc.2011-36.
PMID: 24381377 [PubMed] Free PMC Article
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8.Constraint-induced movement therapy: a method for harnessing neuroplasticity to treat motor disorders.
Uswatte G, Taub E.
Prog Brain Res. 2013;207:379-401. doi: 10.1016/B978-0-444-63327-9.00015-1.
PMID: 24309263 [PubMed – in process]
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9.Principles of neuroplasticity-based rehabilitation.
Nahum M, Lee H, Merzenich MM.
Prog Brain Res. 2013;207:141-71. doi: 10.1016/B978-0-444-63327-9.00009-6.
PMID: 24309254 [PubMed – in process]
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10.Motor skills training promotes motor functional recovery and induces synaptogenesis in the motor cortex and striatum after intracerebral hemorrhage in rats.
Tamakoshi K, Ishida A, Takamatsu Y, Hamakawa M, Nakashima H, Shimada H, Ishida K.
Behav Brain Res. 2014 Mar 1;260:34-43. doi: 10.1016/j.bbr.2013.11.034. Epub 2013 Dec 1.
PMID: 24304717 [PubMed – in process]
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11.The effectiveness of a single session of Whole-Body Vibration in improving the balance and the strength in type 2 diabetic patients with mild to moderate degree of peripheral neuropathy: a pilot study.
Kordi Yoosefinejad A, Shadmehr A, Olyaei G, Talebian S, Bagheri H.
J Bodyw Mov Ther. 2014 Jan;18(1):82-6. doi: 10.1016/j.jbmt.2013.10.007. Epub 2013 Nov 7.
PMID: 24411154 [PubMed – in process]
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12.Therapeutic effects of fenofibrate on diabetic peripheral neuropathy by improving endothelial and neural survival in db/db mice.
Cho YR, Lim JH, Kim MY, Kim TW, Hong BY, Kim YS, Chang YS, Kim HW, Park CW.
PLoS One. 2014 Jan 2;9(1):e83204. doi: 10.1371/journal.pone.0083204. eCollection 2014.
PMID: 24392081 [PubMed – in process] Free PMC Article
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13.Exercise interventions, gait, and balance in older subjects with distal symmetric polyneuropathy: a three-group randomized clinical trial.
Quigley PA, Bulat T, Schulz B, Friedman Y, Hart-Hughes S, Richardson JK, Barnett S.
Am J Phys Med Rehabil. 2014 Jan;93(1):1-12; quiz 13-6. doi: 10.1097/PHM.0000000000000052.
PMID: 24355993 [PubMed – indexed for MEDLINE]
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14.Balance rehabilitation: promoting the role of virtual reality in patients with diabetic peripheral neuropathy.
Grewal GS, Sayeed R, Schwenk M, Bharara M, Menzies R, Talal TK, Armstrong DG, Najafi B.
J Am Podiatr Med Assoc. 2013 Nov-Dec;103(6):498-507.
PMID: 24297986 [PubMed – in process]
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15.[Efficacy observation of carpal tunnel syndrome treated with electroacupuncture].
Xia Q, Liu XW, Wang XL, Tao Y.
Zhongguo Zhen Jiu. 2013 Aug;33(8):700-2. Chinese.
PMID: 24195210 [PubMed – indexed for MEDLINE]
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16.Using Peripheral Nerve Stimulation (PNS) to Treat Neuropathic Pain: A Clinical Series.
Reverberi C, Dario A, Barolat G, Zuccon G.
Neuromodulation. 2014 Feb 14. doi: 10.1111/ner.12157. [Epub ahead of print]
PMID: 24528884 [PubMed – as supplied by publisher]
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17.Electrical stimulation as an adjunctive treatment of painful and sensory diabetic neuropathy.
Thakral G, Kim PJ, LaFontaine J, Menzies R, Najafi B, Lavery LA.
J Diabetes Sci Technol. 2013 Sep 1;7(5):1202-9.
PMID: 24124947 [PubMed – in process]
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18.Diabetic autonomic neuropathy affects symptom generation and brain-gut axis.
Brock C, Søfteland E, Gunterberg V, Frøkjær JB, Lelic D, Brock B, Dimcevski G, Gregersen H, Simrén M, Drewes AM.
Diabetes Care. 2013 Nov;36(11):3698-705. doi: 10.2337/dc13-0347. Epub 2013 Sep 11.
PMID: 24026548 [PubMed – in process]
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19.Electroacupuncture for chemotherapy-induced peripheral neuropathy: study protocol for a pilot multicentre randomized, patient-assessor-blinded, controlled trial.
Kim JH, Kim EJ, Seo BK, Lee S, Lee S, Jung SY, Lee MH, Kim AR, Park HJ, Shin MS, Choi SM.
Trials. 2013 Aug 14;14:254. doi: 10.1186/1745-6215-14-254.
PMID: 23945074 [PubMed – indexed for MEDLINE] Free PMC Article
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20.A novel plantar stimulation technology for improving protective sensation and postural control in patients with diabetic peripheral neuropathy: a double-blinded, randomized study.
Najafi B, Crews RT, Wrobel JS.
Gerontology. 2013;59(5):473-80. doi: 10.1159/000352072. Epub 2013 Jul 16.
PMID: 23860103 [PubMed – in process] Free Article
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  1. Thanks Doctor.
    I appreciate all your help in the videos btw.
    I’ve had Fibromyalgia for nearly 40 years.

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