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Today’s hangout will be on natural IBS remedies. Dr. Gates will be going over the main causes and symptoms of IBS and natural remedies he has found to work with his patients as well as what the current research is showing.
| 1. | A study of the methodological and clinical validity of the combined lactulose hydrogen breath test with scintigraphic oro-cecal transit test for diagnosing small intestinal bacterial overgrowth in IBS patients. |
| Zhao J, Zheng X, Chu H, Zhao J, Cong Y, Fried M, Fox M, Dai N. | |
| Neurogastroenterol Motil. 2014 Mar 18. doi: 10.1111/nmo.12331. [Epub ahead of print] | |
| PMID: 24641100 [PubMed – as supplied by publisher] | |
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| 2. | Irritable bowel syndrome and small intestinal bacterial overgrowth: meaningful association or unnecessary hype. |
| Ghoshal UC, Srivastava D. | |
| World J Gastroenterol. 2014 Mar 14;20(10):2482-91. doi: 10.3748/wjg.v20.i10.2482. Review. | |
| PMID: 24627585 [PubMed – in process] Free PMC Article | |
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| 3. | Overgrowth of the indigenous gut microbiome and irritable bowel syndrome. |
| Bye W, Ishaq N, Bolin TD, Duncombe VM, Riordan SM. | |
| World J Gastroenterol. 2014 Mar 14;20(10):2449-55. doi: 10.3748/wjg.v20.i10.2449. Review. | |
| PMID: 24627582 [PubMed – in process] Free PMC Article | |
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| 4. | Small intestinal bacterial overgrowth produces symptoms in irritable bowel syndrome which are improved by rifaximin. A pilot study. |
| Moraru IG, Portincasa P, Moraru AG, Diculescu M, Dumitra?cu DL. | |
| Rom J Intern Med. 2013 Jul-Dec;51(3-4):143-7. | |
| PMID: 24620626 [PubMed – in process] | |
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| 5. | Review article: bacteria and pathogenesis of disease in the upper gastrointestinal tract–beyond the era of Helicobacter pylori. |
| Walker MM, Talley NJ. | |
| Aliment Pharmacol Ther. 2014 Apr;39(8):767-79. doi: 10.1111/apt.12666. Epub 2014 Feb 24. | |
| PMID: 24612362 [PubMed – in process] | |
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| 6. | [Irritable bowel syndrome: a functional disorder?]. |
| Man F, Bustos Fernández LM. | |
| Acta Gastroenterol Latinoam. 2013 Dec;43(4):321-34. Review. Spanish. | |
| PMID: 24516961 [PubMed – indexed for MEDLINE] | |
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| 7. | Motility abnormalities in irritable bowel syndrome. |
| Dupont AW, Jiang ZD, Harold SA, Snyder N, Galler GW, Garcia-Torres F, Dupont HL. | |
| Digestion. 2014;89:119-23. doi: 10.1159/000356314. Epub 2014 Feb 6. | |
| PMID: 24503633 [PubMed – in process] | |
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| 8. | In vitro activity of rifaximin against isolates from patients with small intestinal bacterial overgrowth. |
| Pistiki A, Galani I, Pyleris E, Barbatzas C, Pimentel M, Giamarellos-Bourboulis EJ. | |
| Int J Antimicrob Agents. 2014 Mar;43(3):236-41. doi: 10.1016/j.ijantimicag.2013.12. | |
| PMID: 24461710 [PubMed – in process] | |
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| 9. | Relationship of cytokines, oxidative stress and GI motility with bacterial overgrowth in ulcerative colitis patients. |
| Rana SV, Sharma S, Kaur J, Prasad KK, Sinha SK, Kochhar R, Malik A, Morya RK. | |
| J Crohns Colitis. 2014 Jan 20. pii: S1873-9946(14)00011-7. doi: 10.1016/j.crohns.2014.01.007. [Epub ahead of print] | |
| PMID: 24456736 [PubMed – as supplied by publisher] | |
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| 10. | Small intestinal bacterial overgrowth: what it is and what it is not. |
| Quigley EM. | |
| Curr Opin Gastroenterol. 2014 Mar;30(2):141-6. doi: 10.1097/MOG.0000000000000040. | |
| PMID: 24406476 [PubMed – in process] | |
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| 11. | The impact of alcohol consumption and cholecystectomy on small intestinal bacterial overgrowth. |
| Gabbard SL, Lacy BE, Levine GM, Crowell MD. | |
| Dig Dis Sci. 2014 Mar;59(3):638-44. doi: 10.1007/s10620-013-2960-y. Epub 2013 Dec 10. | |
| PMID: 24323179 [PubMed – indexed for MEDLINE] | |
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| 12. | [The composition of the gastrointestinal mucosa-associated microbiota in irritable bowel syndrome patients]. |
| Loranskaia ID, Boldyreva MN, Lavrent’eva OA. | |
| Eksp Klin Gastroenterol. 2013;(3):15-22. Russian. | |
| PMID: 24294767 [PubMed – indexed for MEDLINE] | |
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| 13. | Comparison of the antibacterial activity of essential oils and extracts of medicinal and culinary herbs to investigate potential new treatments for irritable bowel syndrome. |
| Thompson A, Meah D, Ahmed N, Conniff-Jenkins R, Chileshe E, Phillips CO, Claypole TC, Forman DW, Row PE. | |
| BMC Complement Altern Med. 2013 Nov 28;13:338. doi: 10.1186/1472-6882-13-338. | |
| PMID: 24283351 [PubMed – in process] Free Article | |
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| 14. | Antinociceptive effect of berberine on visceral hypersensitivity in rats. |
| Tang QL, Lai ML, Zhong YF, Wang AM, Su JK, Zhang MQ. | |
| World J Gastroenterol. 2013 Jul 28;19(28):4582-9. doi: 10.3748/wjg.v19.i28.4582. | |
| PMID: 23901236 [PubMed – indexed for MEDLINE] Free PMC Article | |
| Related citations |
| 15. | Effects of berberine on rat jejunal motility. |
| Chen DP, Xiong YJ, Lv BC, Liu FF, Wang L, Tang ZY, Lin Y. | |
| J Pharm Pharmacol. 2013 May;65(5):734-44. doi: 10.1111/jphp.12026. Epub 2013 Jan 25. | |
| PMID: 23600391 [PubMed – indexed for MEDLINE] | |
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| 16. | Pharmacokinetic comparison of berberine in rat plasma after oral administration of berberine hydrochloride in normal and post inflammation irritable bowel syndrome rats. |
| Gong Z, Chen Y, Zhang R, Wang Y, Guo Y, Yang Q, Zhang H, Dong Y, Weng X, Gao S, Zhu X. | |
| Int J Mol Sci. 2014 Jan 2;15(1):456-67. doi: 10.3390/ijms15010456. | |
| PMID: 24451127 [PubMed – in process] Free PMC Article | |
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| 17. | Breath Testing for Small Intestinal Bacterial Overgrowth: Maximizing Test Accuracy. |
| Saad RJ, Chey WD. | |
| Clin Gastroenterol Hepatol. 2013 Oct 1. pii: S1542-3565(13)01468-7. doi: 10.1016/j.cgh.2013.09.055. [Epub ahead of print] | |
| PMID: 24095975 [PubMed – as supplied by publisher] | |
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| 18. | Gastrointestinal bacterial overgrowth: pathogenesis and clinical significance. |
| Sachdev AH, Pimentel M. | |
| Ther Adv Chronic Dis. 2013 Sep;4(5):223-31. doi: 10.1177/2040622313496126. | |
| PMID: 23997926 [PubMed] Free PMC Article | |
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| 19. | Effectiveness of trimethoprim-sulfamethoxazole and metronidazole in the treatment of small intestinal bacterial overgrowth in children living in a slum. |
| Tahan S, Melli LC, Mello CS, Rodrigues MS, Bezerra Filho H, de Morais MB. | |
| J Pediatr Gastroenterol Nutr. 2013 Sep;57(3):316-8. doi: 10.1097/MPG.0b013e3182952e93. | |
| PMID: 23974062 [PubMed – indexed for MEDLINE] | |
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| 20. | Review article: small intestinal bacterial overgrowth–prevalence, clinical features, current and developing diagnostic tests, and treatment. |
| Grace E, Shaw C, Whelan K, Andreyev HJ. | |
| Aliment Pharmacol Ther. 2013 Oct;38(7):674-88. doi: 10.1111/apt.12456. Epub 2013 Aug 20. | |
| PMID: 23957651 [PubMed – in process] | |
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| 21. | Duodenal-mucosal bacteria associated with celiac disease in children. |
| Sánchez E, Donat E, Ribes-Koninckx C, Fernández-Murga ML, Sanz Y. | |
| Appl Environ Microbiol. 2013 Sep;79(18):5472-9. doi: 10.1128/AEM.00869-13. Epub 2013 Jul 8. | |
| PMID: 23835180 [PubMed – indexed for MEDLINE] Free PMC Article | |
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| 22. | Clinical approach and management of chronic diarrhea. |
| Abdullah M, Firmansyah MA. | |
| Acta Med Indones. 2013 Apr;45(2):157-65. Review. | |
| PMID: 23770798 [PubMed – indexed for MEDLINE] Free Article | |
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| 23. | Rifaximin treatment for small intestinal bacterial overgrowth in children with irritable bowel syndrome. |
| Scarpellini E, Giorgio V, Gabrielli M, Filoni S, Vitale G, Tortora A, Ojetti V, Gigante G, Fundarò C, Gasbarrini A. | |
| Eur Rev Med Pharmacol Sci. 2013 May;17(10):1314-20. | |
| PMID: 23740443 [PubMed – indexed for MEDLINE] Free Article | |
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| 24. | The role of small intestinal bacterial overgrowth in Parkinson’s disease. |
| Fasano A, Bove F, Gabrielli M, Petracca M, Zocco MA, Ragazzoni E, Barbaro F, Piano C, Fortuna S, Tortora A, Di Giacopo R, Campanale M, Gigante G, Lauritano EC, Navarra P, Marconi S, Gasbarrini A, Bentivoglio AR. | |
| Mov Disord. 2013 Aug;28(9):1241-9. doi: 10.1002/mds.25522. Epub 2013 May 27. | |
| PMID: 23712625 [PubMed – indexed for MEDLINE] | |
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| 25. | The low FODMAP diet improves gastrointestinal symptoms in patients with irritable bowel syndrome: a prospective study. |
| de Roest RH, Dobbs BR, Chapman BA, Batman B, O’Brien LA, Leeper JA, Hebblethwaite CR, Gearry RB. | |
| Int J Clin Pract. 2013 Sep;67(9):895-903. doi: 10.1111/ijcp.12128. Epub 2013 May 23. | |
| PMID: 23701141 [PubMed – indexed for MEDLINE] | |
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| 26. | [The role of small bowel microflora in the development of secondary lactase deficiency and the possibilities of its treatment with probiotics]. |
| Ruchkina IN, Fadeeva NA, Parfenov AI, Shcherbakov PL, Gubina AV, Poleva NI, Khomeriki SG, Chikunova BZ. | |
| Ter Arkh. 2013;85(2):21-6. Russian. | |
| PMID: 23653934 [PubMed – indexed for MEDLINE] | |
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| 27. | Alteration of the intestinal microbiota as a cause of and a potential therapeutic option in irritable bowel syndrome. |
| König J, Brummer RJ. | |
| Benef Microbes. 2014 Feb 28:1-15. [Epub ahead of print] | |
| PMID: 24583610 [PubMed – as supplied by publisher] Free Article | |
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| 28. | A role for the gut microbiota in IBS. |
| Collins SM. | |
| Nat Rev Gastroenterol Hepatol. 2014 Apr 22. doi: 10.1038/nrgastro.2014.40. [Epub ahead of print] | |
| PMID: 24751910 [PubMed – as supplied by publisher] | |
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| 29. | Post-infectious irritable bowel syndrome: Mechanistic insights into chronic disturbances following enteric infection. |
| Beatty JK, Bhargava A, Buret AG. | |
| World J Gastroenterol. 2014 Apr 14;20(14):3976-3985. Review. | |
| PMID: 24744587 [PubMed – as supplied by publisher] Free PMC Article | |
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| 30. | Intestinal permeability defects: is it time to treat? |
| Odenwald MA, Turner JR. | |
| Clin Gastroenterol Hepatol. 2013 Sep;11(9):1075-83. doi: 10.1016/j.cgh.2013.07.001. Epub 2013 Jul 12. Review. | |
| PMID: 23851019 [PubMed – indexed for MEDLINE] | |
| Related citations |
| 31. | Leaky gut in patients with diarrhea-predominant irritable bowel syndrome and inactive ulcerative colitis. |
| Gecse K, Róka R, Séra T, Rosztóczy A, Annaházi A, Izbéki F, Nagy F, Molnár T, Szepes Z, Pávics L, Bueno L, Wittmann T. | |
| Digestion. 2012;85(1):40-6. doi: 10.1159/000333083. Epub 2011 Dec 14. | |
| PMID: 22179430 [PubMed – indexed for MEDLINE] | |
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| 32. | Anxiety and depression comorbidities in irritable bowel syndrome (IBS): a systematic review and meta-analysis. |
| Fond G, Loundou A, Hamdani N, Boukouaci W, Dargel A, Oliveira J, Roger M, Tamouza R, Leboyer M, Boyer L. | |
| Eur Arch Psychiatry Clin Neurosci. 2014 Apr 6. [Epub ahead of print] | |
| PMID: 24705634 [PubMed – as supplied by publisher] | |
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| 33. | Long-term efficacy and safety of otilonium bromide in the management of irritable bowel syndrome: a literature review. |
| Triantafillidis JK, Malgarinos G. | |
| Clin Exp Gastroenterol. 2014 Apr 7;7:75-82. eCollection 2014. Review. | |
| PMID: 24741324 [PubMed – as supplied by publisher] Free PMC Article | |
| Related citations |
| 34. | Efficacy and tolerability of renzapride in irritable bowel syndrome: a meta-analysis of randomized, controlled clinical trials including 2528 patients. |
| Mozaffari S, Nikfar S, Abdollahi M. | |
| Arch Med Sci. 2014 Feb 24;10(1):10-18. Epub 2014 Feb 23. Review. | |
| PMID: 24701208 [PubMed – as supplied by publisher] Free PMC Article | |
| Related citations |
| 35. | Emerging role of probiotics and antimicrobials in the management of irritable bowel syndrome. |
| Cash BD. | |
| Curr Med Res Opin. 2014 Apr 14. [Epub ahead of print] | |
| PMID: 24666019 [PubMed – as supplied by publisher] | |
| Related citations |
| 36. | Review article: evidence for the role of gut microbiota in irritable bowel syndrome and its potential influence on therapeutic targets. |
| Dupont HL. | |
| Aliment Pharmacol Ther. 2014 May;39(10):1033-42. doi: 10.1111/apt.12728. Epub 2014 Mar 25. | |
| PMID: 24665829 [PubMed – in process] | |
| Related citations |
| 37. | Motility response to colonic distention is increased in postinfectious irritable bowel syndrome (PI-IBS). |
| Kanazawa M, Palsson OS, van Tilburg MA, Gangarosa LM, Fukudo S, Whitehead WE. | |
| Neurogastroenterol Motil. 2014 May;26(5):696-704. doi: 10.1111/nmo.12318. Epub 2014 Feb 13. | |
| PMID: 24602083 [PubMed – in process] | |
| Related citations |
| 38. | Are there any different effects of Bifidobacterium, Lactobacillus and Streptococcus on intestinal sensation, barrier function and intestinal immunity in PI-IBS mouse model? |
| Wang H, Gong J, Wang W, Long Y, Fu X, Fu Y, Qian W, Hou X. | |
| PLoS One. 2014 Mar 3;9(3):e90153. doi: 10.1371/journal.pone.0090153. eCollection 2014. | |
| PMID: 24595218 [PubMed – in process] Free PMC Article | |
| Related citations |
| 39. | Rifaximin alters intestinal bacteria and prevents stress-induced gut inflammation and visceral hyperalgesia in rats. |
| Xu D, Gao J, Gillilland M 3rd, Wu X, Song I, Kao JY, Owyang C. | |
| Gastroenterology. 2014 Feb;146(2):484-96.e4. doi: 10.1053/j.gastro.2013.10.026. Epub 2013 Oct 22. | |
| PMID: 24161699 [PubMed – indexed for MEDLINE] | |
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| 40. | Interaction between preprandial and postprandial rectal sensory and motor abnormalities in IBS. |
| Törnblom H, Van Oudenhove L, Tack J, Simrén M. | |
| Gut. 2013 Oct 18. doi: 10.1136/gutjnl-2013-305853. [Epub ahead of print] | |
| PMID: 24142965 [PubMed – as supplied by publisher] | |
| Related citations |
| 41. | [Importance of diet in irritable bowel syndrome]. |
| Mearin F, Peña E, Balboa A. | |
| Gastroenterol Hepatol. 2014 May;37(5):302-10. doi: 10.1016/j.gastrohep.2013.12. | |
| PMID: 24582764 [PubMed – in process] | |
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Fabulous talk Dr. G.!!! I really learned a lot. Thanks for the clear roadmap to better health.