Today we are discussing restless leg syndrome. We have done several broadcasts on restless leg syndrome, however today we are going to tie the separate pieces together so that you as the restless leg suffer, or loved one of a restless leg suffer, has a better idea as to the causes of the condition as well as the natural management strategies that are available.
Please enjoy, and send us your questions. Please forward us any questions here on our website or go to our Power Health Facebook page http://powerhealthreno.com/Facebook
References:
| 1. | Altered Brain iron homeostasis and dopaminergic function in Restless Legs Syndrome (Willis-Ekbom Disease). |
| Earley CJ, Connor J, Garcia-Borreguero D, Jenner P, Winkelman J, Zee PC, Allen R. | |
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| 2. | Prevalence of restless legs syndrome in an urban population of eastern Africa (Tanzania). |
| Burtscher C, Baxmann A, Kassubek J, Hornyak M, Matuja W, Schmutzhard E, Winkler AS. | |
| J Neurol Sci. 2014 Nov 15;346(1-2):121-7. doi: 10.1016/j.jns.2014.08.007. Epub 2014 Aug 14. | |
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| 3. | Gray matter alteration in patients with restless legs syndrome: a voxel-based morphometry study. |
| Chang Y, Chang HW, Song H, Ku J, Earley CJ, Allen RP, Cho YW. | |
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| 4. | Painful Restless Legs Syndrome: A Severe, Burning Form of the Disease. |
| Karroum EG, Golmard JL, Leu-Semenescu S, Arnulf I. | |
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| 5. | The effect of vitamin D supplements on the severity of restless legs syndrome. |
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| 7. | Effect of sensory stimuli on restless legs syndrome: a randomized crossover study. |
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| 8. | Restless leg syndrome and sleep quality in lumbar radiculopathy patients. |
| Kocabicak E, Terzi M, Akpinar K, Paksoy K, Cebeci I, Iyigun O. | |
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| 9. | Mood disorders in restless legs syndrome (Willis-Ekbom disease). |
| Becker PM, Sharon D. | |
| J Clin Psychiatry. 2014 Jul;75(7):e679-94. doi: 10.4088/JCP.13r08692. Review. | |
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| 10. | Profile of altered brain iron acquisition in restless legs syndrome. |
| Connor JR, Ponnuru P, Wang XS, Patton SM, Allen RP, Earley CJ. | |
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| 11. | Gray matter anomalies in anterior cingulate cortex as a correlate of depressive symptoms in drug-naïve idiopathic restless legs syndrome. |
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| 12. | New treatment options for the management of restless leg syndrome. |
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| 13. | An update on restless legs syndrome (Willis-Ekbom disease): clinical features, pathogenesis and treatment. |
| Garcia-Borreguero D, Williams AM. | |
| Curr Opin Neurol. 2014 Aug;27(4):493-501. doi: 10.1097/WCO.0000000000000117. Review. | |
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| 14. | Differentiating nocturnal leg cramps and restless legs syndrome. |
| Rana AQ, Khan F, Mosabbir A, Ondo W. | |
| Expert Rev Neurother. 2014 Jul;14(7):813-8. doi: 10.1586/14737175.2014.927734. Epub 2014 Jun 14. Review. | |
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| 15. | Quality of life in patients with primary restless leg syndrome: community-based study. |
| Svetel MV, Jovic JS, Pekmezovic TD, Kostic VS. | |
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| 16. | Restless legs syndrome in end stage renal disease patients on haemodialysis. |
| Haider I, Anees M, Shahid SA. | |
| Pak J Med Sci. 2014 Nov-Dec;30(6):1209-12. doi: 10.12669/pjms.306.5691. | |
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| 17. | Sleep patterns and sleep disturbances across pregnancy. |
| Mindell JA, Cook RA, Nikolovski J. | |
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| 18. | Blood withdrawal affects iron store dynamics in primates with consequences on monoaminergic system function. |
| Hyacinthe C, De Deurwaerdere P, Thiollier T, Li Q, Bezard E, Ghorayeb I. | |
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| 19. | Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands. |
| Keck TM, Banala AK, Slack RD, Burzynski C, Bonifazi A, Okunola-Bakare OM, Moore M, Deschamps JR, Rais R, Slusher BS, Hauck Newman A. | |
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| 21. | Restless legs syndrome and hypothyroidism. |
| Rodríguez Martín C, Miranda Riaño S, Celorrio San Miguel M, Prieto de Paula JM. | |
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| 22. | Presenting features of idiopathic versus secondary restless legs syndrome in pregnancy. |
| Miri S, Rohani M, Vahdat M, Kashanian M, Sariri E, Zamani B, Shahidi GA. | |
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| 23. | An Evidence-based Analysis of the Association between Periodic Leg Movements during Sleep and Arousals in Restless Legs Syndrome. |
| Ferri R, Rundo F, Zucconi M, Manconi M, Bruni O, Ferini-Strambi L, Fulda S. | |
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| 24. | Transcranial direct current stimulation on primary sensorimotor area has no effect in patients with drug-naïve restless legs syndrome: a proof-of-concept clinical trial. |
| Koo YS, Kim SM, Lee C, Lee BU, Moon YJ, Cho YW, Im CH, Choi JW, Kim KH, Jung KY. | |
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| 25. | Association Between Restless Legs Syndrome and Adult ADHD in a German Community-Based Sample. |
| Roy M, de Zwaan M, Tuin I, Philipsen A, Brähler E, Müller A. | |
| J Atten Disord. 2015 Jan 2. pii: 1087054714561291. [Epub ahead of print] | |
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| 26. | Consensus clinical practice guidelines for the diagnosis and treatment of restless legs syndrome/Willis-Ekbom disease during pregnancy and lactation. |
| Picchietti DL, Hensley JG, Bainbridge JL, Lee KA, Manconi M, McGregor JA, Silver RM, Trenkwalder C, Walters AS; International Restless Legs Syndrome Study Group (IRLSSG). | |
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| 27. | Direct comparison of cortical excitability to transcranial magnetic stimulation in obstructive sleep apnea syndrome and restless legs syndrome. |
| Lanza G, Lanuzza B, Aricò D, Cantone M, Cosentino FI, Pennisi M, Bella R, Pennisi G, Ferri R. | |
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| 28. | Pramipexole for Chinese people with primary restless legs syndrome: a 12-week multicenter, randomized, double-blind study. |
| Zhang J, Liu B, Zheng Y, Chu T, Yang Z. | |
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| 29. | Efficacy of the Low-Dose Saccharum Iron Treatment of Idiopathic Restless Legs Syndrome. |
| Zhang X, Chen WW, Huang WJ. | |
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| 30. | Spontaneous aching pain and peculiar involuntary movements: a case report of painful legs and moving toes and review of the literature. |
| Fan YY, Xu Y, Gao XG. | |
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| 31. | Neurocognitive function in patients with idiopathic Restless Legs Syndrome before and after treatment with dopamine-agonist. |
| Galbiati A, Marelli S, Giora E, Zucconi M, Oldani A, Ferini-Strambi L. | |
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| 32. | What patients do to counteract the symptoms of Willis-Ekbom disease (RLS/WED): Effect of gender and severity of illness. |
| Gupta R, Goel D, Ahmed S, Dhar M, Lahan V. | |
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| 33. | Design and validation of a periodic leg movement detector. |
| Moore H 4th, Leary E, Lee SY, Carrillo O, Stubbs R, Peppard P, Young T, Widrow B, Mignot E. | |
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| 34. | Association of Restless Legs Syndrome, Pain, and Mood Disorders in Parkinson’s Disease. |
| Rana AQ, Qureshi AR, Rahman L, Jesudasan A, Hafez KK, Rana MA. | |
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| 35. | Restless legs syndrome in multiple sclerosis. |
| Sieminski M, Losy J, Partinen M. | |
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| 36. | Response to intravenous iron in patients with iron deficiency anemia (IDA) and restless leg syndrome (Willis-Ekbom disease). |
| Mehmood T, Auerbach M, Earley CJ, Allen RP. | |
| Sleep Med. 2014 Dec;15(12):1473-6. doi: 10.1016/j.sleep.2014.08.012. Epub 2014 Sep 10. | |
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| 37. | The cerebellum and sleep. |
| DelRosso LM, Hoque R. | |
| Neurol Clin. 2014 Nov;32(4):893-900. doi: 10.1016/j.ncl.2014.07.003. Epub 2014 Oct 24. | |
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| 38. | Structural brain lesions and restless legs syndrome: a cross-sectional population-based study. |
| Rist PM, Tzourio C, Elbaz A, Soumaré A, Dufouil C, Mazoyer B, Kurth T. | |
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| 39. | Increased nocturnal periodic limb movements in rheumatoid arthritis patients meeting questionnaire diagnostic criteria for restless legs syndrome. |
| Taylor-Gjevre RM, Gjevre JA, Nair BV. | |
| BMC Musculoskelet Disord. 2014 Nov 18;15:378. doi: 10.1186/1471-2474-15-378. | |
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| 40. | Does idiopathic restless legs syndrome delay onset and reduce severity of Parkinson’s disease: a pilot study. |
| Dragan EM, Chen Z, Ondo WG. | |
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| 41. | The gut microbiome and the brain. |
| Galland L. | |
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| 42. | A novel model for brain iron uptake: introducing the concept of regulation. |
| Simpson IA, Ponnuru P, Klinger ME, Myers RL, Devraj K, Coe CL, Lubach GR, Carruthers A, Connor JR. | |
| J Cereb Blood Flow Metab. 2015 Jan;35(1):48-57. doi: 10.1038/jcbfm.2014.168. Epub 2014 Oct 15. | |
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| 43. | A review of current treatment strategies for restless legs syndrome (Willis-Ekbom disease). |
| Klingelhoefer L, Cova I, Gupta S, Chaudhuri KR. | |
| Clin Med. 2014 Oct;14(5):520-4. doi: 10.7861/clinmedicine.14-5-520. | |
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| 44. | Is autonomic nervous system involved in restless legs syndrome during wakefulness? |
| Izzi F, Placidi F, Romigi A, Lauretti B, Marfia GA, Mercuri NB, Marciani MG, Rocchi C. | |
| Sleep Med. 2014 Nov;15(11):1392-7. doi: 10.1016/j.sleep.2014.06.022. Epub 2014 Aug 22. | |
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