PHT Live – Small Intestinal Bacterial Overgrowth – SIBO

Today we will be talking about SIBO.
SIBO stands for small intestinal bacterial overgrowth, and is a relatively newly acknowledged entity which causes symptoms of irritable bowel syndrome (IBS).  Because many of our patients have IBS as well as SIBO, we wanted to take today to discuss the new findings regarding SIBO in how it is diagnosed as well as how it is treated.
Please enjoy, and send us your questions.  Please forward us any questions here on our website or go to our Power Health Facebook page


1.Skin microbiome and skin disease: the example of rosacea.
Picardo M, Ottaviani M.
J Clin Gastroenterol. 2014 Nov-Dec;48 Suppl 1:S85-6. doi: 10.1097/MCG.0000000000000241.
PMID: 25291137 [PubMed – in process]
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2.Hydrogen breath tests in gastrointestinal diseases.
Rana SV, Malik A.
Indian J Clin Biochem. 2014 Oct;29(4):398-405. doi: 10.1007/s12291-014-0426-4. Epub 2014 Mar 21. Review.
PMID: 25298621 [PubMed]
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3.Small intestinal bacterial overgrowth in patients with chronic pancreatitis.
Signoretti M, Stigliano S, Valente R, Piciucchi M, Delle Fave G, Capurso G.
J Clin Gastroenterol. 2014 Nov-Dec;48 Suppl 1:S52-5. doi: 10.1097/MCG.0000000000000238.
PMID: 25291129 [PubMed – in process]
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4.Short-term probiotic therapy alleviates small intestinal bacterial overgrowth, but does not improve intestinal permeability in chronic liver disease.
Kwak DS, Jun DW, Seo JG, Chung WS, Park SE, Lee KN, Khalid-Saeed W, Lee HL, Lee OY, Yoon BC, Choi HS.
Eur J Gastroenterol Hepatol. 2014 Sep 19. [Epub ahead of print]
PMID: 25244414 [PubMed – as supplied by publisher]
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5.The biopsy pathology of non-coeliac enteropathy.
Greenson JK.
Histopathology. 2014 Sep 18. doi: 10.1111/his.12522. [Epub ahead of print]
PMID: 25234408 [PubMed – as supplied by publisher]
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6.Small intestinal bacterial overgrowth is common both among patients with alcoholic and idiopathic chronic pancreatitis.
Kumar K, Ghoshal UC, Srivastava D, Misra A, Mohindra S.
Pancreatology. 2014 Jul-Aug;14(4):280-3. doi: 10.1016/j.pan.2014.05.792. Epub 2014 May 27.
PMID: 25062877 [PubMed – in process]
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7.Liquid melevodopa versus standard levodopa in patients with Parkinson disease and small intestinal bacterial overgrowth.
Fasano A, Bove F, Gabrielli M, Ragazzoni E, Fortuna S, Tortora A, Zocco MA, Marconi S, Gasbarrini A, Bentivoglio AR.
Clin Neuropharmacol. 2014 Jul-Aug;37(4):91-5. doi: 10.1097/WNF.0000000000000034.
PMID: 24992085 [PubMed – in process]
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8.[Estimation of small intestinal bacterial overgrowth in patients with constipation and diarrhea irritable bowel syndrome].
?okie? K, Klupi?ska G, Walecka-Kapica E, B?o?ska A.
Pol Merkur Lekarski. 2014 May;36(215):307-10. Polish.
PMID: 24964506 [PubMed – indexed for MEDLINE]
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9.Link between hypothyroidism and small intestinal bacterial overgrowth.
Patil AD.
Indian J Endocrinol Metab. 2014 May;18(3):307-9. doi: 10.4103/2230-8210.131155. Review.
PMID: 24944923 [PubMed] Free PMC Article
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10.[Microbiota, gastrointestinal infections, low-grade inflammation, and antibiotic therapy in irritable bowel syndrome: an evidence-based review].
Schmulson M, Bielsa MV, Carmona-Sánchez R, Hernández A, López-Colombo A, López Vidal Y, Peláez-Luna M, Remes-Troche JM, Tamayo JL, Valdovinos MA.
Rev Gastroenterol Mex. 2014 Apr-Jun;79(2):96-134. doi: 10.1016/j.rgmx.2014.01.004. Epub 2014 May 23. Spanish.
PMID: 24857420 [PubMed – in process]
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11.Breath tests in the diagnosis of small intestinal bacterial overgrowth in patients with irritable bowel syndrome in comparison with quantitative upper gut aspirate culture.
Ghoshal UC, Srivastava D, Ghoshal U, Misra A.
Eur J Gastroenterol Hepatol. 2014 Jul;26(7):753-60. doi: 10.1097/MEG.0000000000000122.
PMID: 24849768 [PubMed – in process]
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12.Unclear abdominal discomfort: pivotal role of carbohydrate malabsorption.
Goebel-Stengel M, Stengel A, Schmidtmann M, Voort Iv, Kobelt P, Mönnikes H.
J Neurogastroenterol Motil. 2014 Apr 30;20(2):228-35. doi: 10.5056/jnm.2014.20.2.228.
PMID: 24840375 [PubMed] Free PMC Article
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13.Low ileocecal valve pressure is significantly associated with small intestinal bacterial overgrowth (SIBO).
Roland BC, Ciarleglio MM, Clarke JO, Semler JR, Tomakin E, Mullin GE, Pasricha PJ.
Dig Dis Sci. 2014 Jun;59(6):1269-77. doi: 10.1007/s10620-014-3166-7. Epub 2014 May 3.
PMID: 24795035 [PubMed – indexed for MEDLINE]
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14.Small intestinal bacterial overgrowth in Parkinson’s disease.
Tan AH, Mahadeva S, Thalha AM, Gibson PR, Kiew CK, Yeat CM, Ng SW, Ang SP, Chow SK, Tan CT, Yong HS, Marras C, Fox SH, Lim SY.
Parkinsonism Relat Disord. 2014 May;20(5):535-40. doi: 10.1016/j.parkreldis.2014.02.019. Epub 2014 Mar 2.
PMID: 24637123 [PubMed – in process]
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15.Small intestinal bacterial overgrowth produces symptoms in irritable bowel syndrome which are improved by rifaximin. A pilot study.
Moraru IG, Portincasa P, Moraru AG, Diculescu M, Dumitra?cu DL.
Rom J Intern Med. 2013 Jul-Dec;51(3-4):143-7.
PMID: 24620626 [PubMed – indexed for MEDLINE]
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16.Prolonged orocecal transit time enhances serum bile acids through bacterial overgrowth, contributing factor to gallstone disease.
Kaur J, Rana SV, Gupta R, Gupta V, Sharma SK, Dhawan DK.
J Clin Gastroenterol. 2014 Apr;48(4):365-9. doi: 10.1097/MCG.0b013e3182a14fba.
PMID: 24598592 [PubMed – in process]
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17.Relationship of cytokines, oxidative stress and GI motility with bacterial overgrowth in ulcerative colitis patients.
Rana SV, Sharma S, Kaur J, Prasad KK, Sinha SK, Kochhar R, Malik A, Morya RK.
J Crohns Colitis. 2014 Aug 1;8(8):859-65. doi: 10.1016/j.crohns.2014.01.007. Epub 2014 Jan 21.
PMID: 24456736 [PubMed – in process]
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18.In vitro activity of rifaximin against isolates from patients with small intestinal bacterial overgrowth.
Pistiki A, Galani I, Pyleris E, Barbatzas C, Pimentel M, Giamarellos-Bourboulis EJ.
Int J Antimicrob Agents. 2014 Mar;43(3):236-41. doi: 10.1016/j.ijantimicag.2013.12.008. Epub 2014 Jan 6.
PMID: 24461710 [PubMed – in process]
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19.Diagnosis of small intestinal bacterial overgrowth in the clinical practice.
Gabrielli M, D’Angelo G, Di Rienzo T, Scarpellini E, Ojetti V.
Eur Rev Med Pharmacol Sci. 2013;17 Suppl 2:30-5.
PMID: 24443065 [PubMed – in process] Free Article
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20.Role of small intestinal bacterial overgrowth in severe small intestinal damage in chronic non-steroidal anti-inflammatory drug users.
Muraki M, Fujiwara Y, Machida H, Okazaki H, Sogawa M, Yamagami H, Tanigawa T, Shiba M, Watanabe K, Tominaga K, Watanabe T, Arakawa T.
Scand J Gastroenterol. 2014 Mar;49(3):267-73. doi: 10.3109/00365521.2014.880182. Epub 2014 Jan 13.
PMID: 24417613 [PubMed – in process]
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21.Small intestinal bacterial overgrowth: what it is and what it is not.
Quigley EM.
Curr Opin Gastroenterol. 2014 Mar;30(2):141-6. doi: 10.1097/MOG.0000000000000040. Review.
PMID: 24406476 [PubMed – indexed for MEDLINE]
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