PHT Live – Non-Celiac Gluten Sensitivity

To Watch Live Hangout hit the play button we will be starting around 10am PST
Have questions?  Ask below!

Today we are discussing a very hot topic in the media, termed non celiac gluten sensitivity.  We have had a tremendous amount of feedback from patients regarding reports of a recent study which showed that non-celiac gluten sensitivity does not exist, and even more interestingly the study was conducted by the gentleman who pioneered the diagnosis of non-celiac gluten sensitivity, Peter Gibson.
In today’s hangout we will discuss how the study in question was potentially flawed and how other very important data, published just this year by Peter Gibson, is not consistent with what is being reported in the mainstream news.  So please tune in, enjoy, and forward us your questions!



1.Prevalence of Anti-deamidated Gliadin Peptide Antibodies in Asian Patients With Irritable Bowel Syndrome.
Lu W, Gwee KA, Siah KT, Kang JY, Lee R, Ngan CC.
J Neurogastroenterol Motil. 2014 Apr 30;20(2):236-41. doi: 10.5056/jnm.2014.20.2.236.
PMID: 24840376 [PubMed] Free PMC Article
Related citations
2.Fibromyalgia and non-celiac gluten sensitivity: a description with remission of fibromyalgia.
Isasi C, Colmenero I, Casco F, Tejerina E, Fernandez N, Serrano-Vela JI, Castro MJ, Villa LF.
Rheumatol Int. 2014 Apr 12. [Epub ahead of print]
PMID: 24728027 [PubMed – as supplied by publisher]
Related citations
3.[Non-celiac gluten sensitivity: A critical review of current evidence.]
Molina-Infante J, Santolaria S, Montoro M, Esteve M, Fernández-Bañares F.
Gastroenterol Hepatol. 2014 Mar 22. pii: S0210-5705(14)00051-X. doi: 10.1016/j.gastrohep.2014.01.005. [Epub ahead of print] Spanish.
PMID: 24667093 [PubMed – as supplied by publisher]
Related citations
4.[Clinical features suggesting autism spectrum disorder as a manifestation of non-celiac gluten sensitivity.]
Alonso Canal L, Isasi Zaragoza C, Colmenero Blanco I, Martínez Gómez MJ, Arcas Martínez J.
An Pediatr (Barc). 2014 Mar 18. pii: S1695-4033(14)00099-X. doi: 10.1016/j.anpedi.2014.02.021. [Epub ahead of print] Spanish. No abstract available.
PMID: 24656390 [PubMed – as supplied by publisher] Free Article
Related citations
5.Celiac disease or non-celiac gluten sensitivity? An approach to clinical differential diagnosis.
Kabbani TA, Vanga RR, Leffler DA, Villafuerte-Galvez J, Pallav K, Hansen J, Mukherjee R, Dennis M, Kelly CP.
Am J Gastroenterol. 2014 May;109(5):741-6. doi: 10.1038/ajg.2014.41. Epub 2014 Mar 11.
PMID: 24619056 [PubMed – in process]
Related citations
6.[Importance of diet in irritable bowel syndrome].
Mearin F, Peña E, Balboa A.
Gastroenterol Hepatol. 2014 May;37(5):302-10. doi: 10.1016/j.gastrohep.2013.12.010. Epub 2014 Feb 28. Spanish.
PMID: 24582764 [PubMed – in process]
Related citations
7.Non-celiac gluten sensitivity: literature review.
Mansueto P, Seidita A, D’Alcamo A, Carroccio A.
J Am Coll Nutr. 2014;33(1):39-54. doi: 10.1080/07315724.2014.869996.
PMID: 24533607 [PubMed – in process]
Related citations
8.Gluten and wheat intolerance today: are modern wheat strains involved?
de Lorgeril M, Salen P.
Int J Food Sci Nutr. 2014 Feb 13. [Epub ahead of print]
PMID: 24524657 [PubMed – as supplied by publisher]
Related citations
9.Effect of gluten free diet on immune response to gliadin in patients with non-celiac gluten sensitivity.
Caio G, Volta U, Tovoli F, De Giorgio R.
BMC Gastroenterol. 2014 Feb 13;14:26. doi: 10.1186/1471-230X-14-26.
PMID: 24524388 [PubMed – in process] Free PMC Article
Related citations
10.US perspective on gluten-related diseases.
Leonard MM, Vasagar B.
Clin Exp Gastroenterol. 2014 Jan 24;7:25-37. eCollection 2014. Review.
PMID: 24493932 [PubMed – as supplied by publisher] Free PMC Article
Related citations
11.Diagnosis and classification of celiac disease and gluten sensitivity.
Tonutti E, Bizzaro N.
Autoimmun Rev. 2014 Apr-May;13(4-5):472-6. doi: 10.1016/j.autrev.2014.01.043. Epub 2014 Jan 15. Review.
PMID: 24440147 [PubMed – indexed for MEDLINE]
Related citations
12.Non-celiac gluten sensitivity. Is it in the gluten or the grain?
Nijeboer P, Bontkes HJ, Mulder CJ, Bouma G.
J Gastrointestin Liver Dis. 2013 Dec;22(4):435-40.
PMID: 24369326 [PubMed – in process] Free Article
Related citations
13.Biomarkers of gluten sensitivity in patients with non-affective psychosis: a meta-analysis.
Lachance LR, McKenzie K.
Schizophr Res. 2014 Feb;152(2-3):521-7. doi: 10.1016/j.schres.2013.12.001. Epub 2013 Dec 22.
PMID: 24368154 [PubMed – in process]
Related citations
14.Non-celiac wheat sensitivity is a more appropriate label than non-celiac gluten sensitivity.
Carroccio A, Rini G, Mansueto P.
Gastroenterology. 2014 Jan;146(1):320-1. doi: 10.1053/j.gastro.2013.08.061. Epub 2013 Nov 22. No abstract available.
PMID: 24275240 [PubMed – indexed for MEDLINE]
Related citations
15.No effects of gluten in patients with self-reported non-celiac gluten sensitivity after dietary reduction of fermentable, poorly absorbed, short-chain carbohydrates.
Biesiekierski JR, Peters SL, Newnham ED, Rosella O, Muir JG, Gibson PR.
Gastroenterology. 2013 Aug;145(2):320-8.e1-3. doi: 10.1053/j.gastro.2013.04.051. Epub 2013 May 4.
PMID: 23648697 [PubMed – indexed for MEDLINE]
Related citations
16.Non-celiac wheat sensitivity diagnosed by double-blind placebo-controlled challenge: exploring a new clinical entity.
Carroccio A, Mansueto P, Iacono G, Soresi M, D’Alcamo A, Cavataio F, Brusca I, Florena AM, Ambrosiano G, Seidita A, Pirrone G, Rini GB.
Am J Gastroenterol. 2012 Dec;107(12):1898-906; quiz 1907. doi: 10.1038/ajg.2012.236. Epub 2012 Jul 24.
PMID: 22825366 [PubMed – indexed for MEDLINE]
Related citations
17.Non-Celiac Gluten sensitivity: the new frontier of gluten related disorders.
Catassi C, Bai JC, Bonaz B, Bouma G, Calabrò A, Carroccio A, Castillejo G, Ciacci C, Cristofori F, Dolinsek J, Francavilla R, Elli L, Green P, Holtmeier W, Koehler P, Koletzko S, Meinhold C, Sanders D, Schumann M, Schuppan D, Ullrich R, Vécsei A, Volta U, Zevallos V, Sapone A, Fasano A.
Nutrients. 2013 Sep 26;5(10):3839-53. doi: 10.3390/nu5103839. Review.
PMID: 24077239 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations
18.Is gluten a cause of gastrointestinal symptoms in people without celiac disease?
Biesiekierski JR, Muir JG, Gibson PR.
Curr Allergy Asthma Rep. 2013 Dec;13(6):631-8. doi: 10.1007/s11882-013-0386-4. Review.
PMID: 24026574 [PubMed – indexed for MEDLINE]
Related citations
19.Fibromyalgia and coeliac disease: a media hype or an emerging clinical problem?
Tovoli F, Giampaolo L, Caio G, Monti M, Piscaglia M, Frisoni M, Bolondi L, Volta U.
Clin Exp Rheumatol. 2013 Nov-Dec;31(6 Suppl 79):S50-2. Epub 2013 Sep 9.
PMID: 24021167 [PubMed – indexed for MEDLINE]
Related citations
20.Diagnostic accuracy of a new point-of-care screening assay for celiac disease.
Benkebil F, Combescure C, Anghel SI, Besson Duvanel C, Schäppi MG.
World J Gastroenterol. 2013 Aug 21;19(31):5111-7. doi: 10.3748/wjg.v19.i31.5111.
PMID: 23964145 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations
21.Non-celiac gluten sensitivity: clinical relevance and recommendations for future research.
Mooney PD, Aziz I, Sanders DS.
Neurogastroenterol Motil. 2013 Nov;25(11):864-71. doi: 10.1111/nmo.12216. Epub 2013 Aug 12.
PMID: 23937528 [PubMed – in process]
Related citations
22.Non-celiac gluten sensitivity: questions still to be answered despite increasing awareness.
Volta U, Caio G, Tovoli F, De Giorgio R.
Cell Mol Immunol. 2013 Sep;10(5):383-92. doi: 10.1038/cmi.2013.28. Epub 2013 Aug 10. Review.
PMID: 23934026 [PubMed – indexed for MEDLINE]
Related citations
23.Biochemical modifications of gliadins induced by microbial transglutaminase on wheat flour.
Mazzeo MF, Bonavita R, Maurano F, Bergamo P, Siciliano RA, Rossi M.
Biochim Biophys Acta. 2013 Nov;1830(11):5166-74. doi: 10.1016/j.bbagen.2013.07.021. Epub 2013 Jul 25.
PMID: 23891939 [PubMed – indexed for MEDLINE]
Related citations
24.Gluten ataxia of sporadic and hereditary cerebellar ataxia in patients from mainland China.
Guan WJ, Liu XJ, Tang BS, Liu YT, Zhou Y, Jiang H, Shen L, Xia K, Wang JL.
Neurol India. 2013 May-Jun;61(3):226-30.
PMID: 23860139 [PubMed – indexed for MEDLINE] Free Article
Related citations
25.[Non-coeliac gluten sensitivity: hype, or new epidemic?].
Nijeboer P, Mulder C, Bouma G.
Ned Tijdschr Geneeskd. 2013;157(21):A6168. Review. Dutch.
PMID: 23693012 [PubMed – indexed for MEDLINE]
Related citations
26.The relationship of autism and gluten.
Buie T.
Clin Ther. 2013 May;35(5):578-83. doi: 10.1016/j.clinthera.2013.04.011. Review.
PMID: 23688532 [PubMed – indexed for MEDLINE]
Related citations
27.Randomised clinical trial: gluten may cause depression in subjects with non-coeliac gluten sensitivity – an exploratory clinical study.
Peters SL, Biesiekierski JR, Yelland GW, Muir JG, Gibson PR.
Aliment Pharmacol Ther. 2014 May;39(10):1104-12. doi: 10.1111/apt.12730. Epub 2014 Apr 1.
PMID: 24689456 [PubMed – in process]
Related citations


Leave a Comment

Your email address will not be published. Required fields are marked *