PHT Live – Am I Gluten Intolerant? Symptoms of Gluten Intolerance/Gluten Allergy

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Today’s broadcast is on the highly controversial wheat protein, termed gluten.
Dr. Rutherford and Dr. Gates discuss the systemic manifestations of gluten intolerance.  They also explore the history of gluten related disorders, and the exploding research relative to gluten mediated immune responses as well as the new diagnostic category of non celiac gluten sensitivity.
Great emphasis is placed in the broadcast regarding neurologic diseases that may be completely or in part caused by gluten mediated mechanisms.  Dr. Hadjivassiliou is the one who deserves much of the credit for this, as his pioneering research has led to acceptance of his data within the neurology community.  Furthermore, the handbook of clinical neurology now has a chapter in it solely on gluten related neurologic disorders, written by none other than Dr. Hadjivassiliou.
Please enjoy the broadcast!
1.Neuropathy associated with gluten sensitivity.
Hadjivassiliou M, Grünewald RA, Kandler RH, Chattopadhyay AK, Jarratt JA, Sanders DS, Sharrack B, Wharton SB, Davies-Jones GA.
J Neurol Neurosurg Psychiatry. 2006 Nov;77(11):1262-6. Epub 2006 Jul 11.
PMID: 16835287 [PubMed – indexed for MEDLINE] Free PMC Article
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2.Non-Celiac Gluten sensitivity: the new frontier of gluten related disorders.
Catassi C, Bai JC, Bonaz B, Bouma G, Calabrò A, Carroccio A, Castillejo G, Ciacci C, Cristofori F, Dolinsek J, Francavilla R, Elli L, Green P, Holtmeier W, Koehler P, Koletzko S, Meinhold C, Sanders D, Schumann M, Schuppan D, Ullrich R, Vécsei A, Volta U, Zevallos V, Sapone A, Fasano A.
Nutrients. 2013 Sep 26;5(10):3839-53. doi: 10.3390/nu5103839.
PMID: 24077239 [PubMed – in process] Free PMC Article
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3.Non-celiac gluten sensitivity: clinical relevance and recommendations for future research.
Mooney PD, Aziz I, Sanders DS.
Neurogastroenterol Motil. 2013 Nov;25(11):864-71. doi: 10.1111/nmo.12216. Epub 2013 Aug 12.
PMID: 23937528 [PubMed – in process]
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4.Non-celiac gluten sensitivity: questions still to be answered despite increasing awareness.
Volta U, Caio G, Tovoli F, De Giorgio R.
Cell Mol Immunol. 2013 Sep;10(5):383-92. doi: 10.1038/cmi.2013.28. Epub 2013 Aug 10. Review.
PMID: 23934026 [PubMed – indexed for MEDLINE]
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5.Non-celiac gluten sensitivity. Is it in the gluten or the grain?
Nijeboer P, Bontkes HJ, Mulder CJ, Bouma G.
J Gastrointestin Liver Dis. 2013 Dec;22(4):435-40.
PMID: 24369326 [PubMed – in process] Free Article
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6.Diagnosis and classification of celiac disease and gluten sensitivity.
Tonutti E, Bizzaro N.
Autoimmun Rev. 2014 April – May;13(4-5):472-476. doi: 10.1016/j.autrev.2014.01.043. Epub 2014 Jan 15. Review.
PMID: 24440147 [PubMed – as supplied by publisher]
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7.Biomarkers of gluten sensitivity in patients with non-affective psychosis: a meta-analysis.
Lachance LR, McKenzie K.
Schizophr Res. 2014 Feb;152(2-3):521-7. doi: 10.1016/j.schres.2013.12.001. Epub 2013 Dec 22.
PMID: 24368154 [PubMed – in process]
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8.Non-celiac gluten sensitivity: literature review.
Mansueto P, Seidita A, D’Alcamo A, Carroccio A.
J Am Coll Nutr. 2014;33(1):39-54. doi: 10.1080/07315724.2014.869996.
PMID: 24533607 [PubMed – in process]
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9.Autoantibodies in gluten ataxia recognize a novel neuronal transglutaminase.
Hadjivassiliou M, Aeschlimann P, Strigun A, Sanders DS, Woodroofe N, Aeschlimann D.
Ann Neurol. 2008 Sep;64(3):332-43. doi: 10.1002/ana.21450.
PMID: 18825674 [PubMed – indexed for MEDLINE]
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10.Sensory ganglionopathy due to gluten sensitivity.
Hadjivassiliou M, Rao DG, Wharton SB, Sanders DS, Grünewald RA, Davies-Jones AG.
Neurology. 2010 Sep 14;75(11):1003-8. doi: 10.1212/WNL.0b013e3181f25ee0.
PMID: 20837968 [PubMed – indexed for MEDLINE]
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11.GAD antibody-associated neurological illness and its relationship to gluten sensitivity.
Hadjivassiliou M, Aeschlimann D, Grünewald RA, Sanders DS, Sharrack B, Woodroofe N.
Acta Neurol Scand. 2011 Mar;123(3):175-80. doi: 10.1111/j.1600-0404.2010.01356.x.
PMID: 20456245 [PubMed – indexed for MEDLINE]
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12.Immune-mediated acquired ataxias.
Hadjivassiliou M.
Handb Clin Neurol. 2012;103:189-99. doi: 10.1016/B978-0-444-51892-7.00011-5. Review.
PMID: 21827889 [PubMed – indexed for MEDLINE]
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13.Should we be ‘nervous’ about coeliac disease? Brain abnormalities in patients with coeliac disease referred for neurological opinion.
Currie S, Hadjivassiliou M, Clark MJ, Sanders DS, Wilkinson ID, Griffiths PD, Hoggard N.
J Neurol Neurosurg Psychiatry. 2012 Dec;83(12):1216-21. doi: 10.1136/jnnp-2012-303281. Epub 2012 Aug 20.
PMID: 22906616 [PubMed – indexed for MEDLINE]
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14.MR spectroscopy and atrophy in Gluten, Friedreich’s and SCA6 ataxias.
Hadjivassiliou M, Wallis LI, Hoggard N, Grünewald RA, Griffiths PD, Wilkinson ID.
Acta Neurol Scand. 2012 Aug;126(2):138-43. doi: 10.1111/j.1600-0404.2011.01620.x. Epub 2011 Nov 10.
PMID: 22070551 [PubMed – indexed for MEDLINE]
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15.Transglutaminase 6 antibodies in the diagnosis of gluten ataxia.
Hadjivassiliou M, Aeschlimann P, Sanders DS, Mäki M, Kaukinen K, Grünewald RA, Bandmann O, Woodroofe N, Haddock G, Aeschlimann DP.
Neurology. 2013 May 7;80(19):1740-5. doi: 10.1212/WNL.0b013e3182919070. Epub 2013 Apr 10.
PMID: 23576621 [PubMed – indexed for MEDLINE]
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16.Gluten-related neurologic dysfunction.
Hadjivassiliou M, Duker AP, Sanders DS.
Handb Clin Neurol. 2014;120:607-19. doi: 10.1016/B978-0-7020-4087-0.00041-3.
PMID: 24365341 [PubMed – in process]
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17.Gluten and wheat intolerance today: are modern wheat strains involved?
de Lorgeril M, Salen P.
Int J Food Sci Nutr. 2014 Feb 13. [Epub ahead of print]
PMID: 24524657 [PubMed – as supplied by publisher]
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18.Effect of gluten free diet on immune response to gliadin in patients with non-celiac gluten sensitivity.
Caio G, Volta U, Tovoli F, De Giorgio R.
BMC Gastroenterol. 2014 Feb 13;14:26. doi: 10.1186/1471-230X-14-26.
PMID: 24524388 [PubMed – in process] Free PMC Article
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19.US perspective on gluten-related diseases.
Leonard MM, Vasagar B.
Clin Exp Gastroenterol. 2014 Jan 24;7:25-37. eCollection 2014. Review.
PMID: 24493932 [PubMed – as supplied by publisher] Free PMC Article
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20.Genetic etiology of schizophrenia: possible role of immunoglobulin ? genes.
Pandey JP.
Psychiatr Genet. 2014 Apr;24(2):83-6. doi: 10.1097/YPG.0000000000000017.
PMID: 24572972 [PubMed – in process]
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