Peripheral Neuropathy – The Main Causes and Treatment Options

Today we are discussing Peripheral Neuropathy.  Peripheral Neuropathy is a condition affecting upwards of 20 million adults in the United States and also 1/10 individuals over the age of 65.  Likely you know someone with peripheral neuropathy.  Most patients are informed there is nothing that can be done for this condition, and that they will just have to live with it.  However, today we are presenting the most recent concepts in managing peripheral neuropathy including therapies that do not include medications.Thus far, we have done broadcasts on small fiber peripheral neuropathy and diabetic peripheral neuropathy, but today we are going to talk about the 80+ causes of peripheral neuropathy and how we manage many of these in our office.  In addition, we will be discussing new treatment options for those who suffer with this disabling disorder.

Please enjoy, and send us your questions.  Please forward us any questions here on our website or go to our Power Health Facebook page http://powerhealthreno.com/Facebook
References:
1.Spinal cord stimulation in patients with painful diabetic neuropathy: A multicentre randomized clinical trial.
de Vos CC, Meier K, Zaalberg PB, Nijhuis HJ, Duyvendak W, Vesper J, Enggaard TP, Lenders MW.
Pain. 2014 Aug 29. pii: S0304-3959(14)00390-X. doi: 10.1016/j.pain.2014.08.031. [Epub ahead of print]
PMID: 25180016 [PubMed – as supplied by publisher]
Related citations
2.Burst spinal cord stimulation evaluated in patients with failed back surgery syndrome and painful diabetic neuropathy.
de Vos CC, Bom MJ, Vanneste S, Lenders MW, de Ridder D.
Neuromodulation. 2014 Feb;17(2):152-9. doi: 10.1111/ner.12116. Epub 2013 Sep 24.
PMID: 24655043 [PubMed – in process]
Related citations
3.Using Peripheral Nerve Stimulation (PNS) to Treat Neuropathic Pain: A Clinical Series.
Reverberi C, Dario A, Barolat G, Zuccon G.
Neuromodulation. 2014 Feb 14. doi: 10.1111/ner.12157. [Epub ahead of print]
PMID: 24528884 [PubMed – as supplied by publisher]
Related citations
4.Diabetic autonomic neuropathy affects symptom generation and brain-gut axis.
Brock C, Søfteland E, Gunterberg V, Frøkjær JB, Lelic D, Brock B, Dimcevski G, Gregersen H, Simrén M, Drewes AM.
Diabetes Care. 2013 Nov;36(11):3698-705. doi: 10.2337/dc13-0347. Epub 2013 Sep 11.
PMID: 24026548 [PubMed – in process]
Related citations
5.Differential effects of subcutaneous electrical stimulation (SQS) and transcutaneous electrical nerve stimulation (TENS) in rodent models of chronic neuropathic or inflammatory pain.
Vera-Portocarrero LP, Cordero T, Billstrom T, Swearingen K, Wacnik PW, Johanek LM.
Neuromodulation. 2013 Jul-Aug;16(4):328-35; discussion 335. doi: 10.1111/ner.12037. Epub 2013 Feb 26.
PMID: 23442024 [PubMed – indexed for MEDLINE]
Related citations
6.Peripheral nerve stimulation for chronic neurogenic pain.
Al-Jehani H, Jacques L.
Prog Neurol Surg. 2011;24:27-40. doi: 10.1159/000323017. Epub 2011 Mar 21. Review.
PMID: 21422774 [PubMed – indexed for MEDLINE]
Related citations
7.Effect and safety of spinal cord stimulation for treatment of chronic pain caused by diabetic neuropathy.
de Vos CC, Rajan V, Steenbergen W, van der Aa HE, Buschman HP.
J Diabetes Complications. 2009 Jan-Feb;23(1):40-5. doi: 10.1016/j.jdiacomp.2007.08.002. Epub 2008 Apr 16.
PMID: 18413161 [PubMed – indexed for MEDLINE]
Related citations
8.Peripheral nerve stimulation for neuropathic pain.
Slavin KV.
Neurotherapeutics. 2008 Jan;5(1):100-6. doi: 10.1016/j.nurt.2007.11.005. Review.
PMID: 18164488 [PubMed – indexed for MEDLINE]
Related citations
9.The appropriate use of neurostimulation of the spinal cord and peripheral nervous system for the treatment of chronic pain and ischemic diseases: the Neuromodulation Appropriateness Consensus Committee.
Deer TR, Mekhail N, Provenzano D, Pope J, Krames E, Leong M, Levy RM, Abejon D, Buchser E, Burton A, Buvanendran A, Candido K, Caraway D, Cousins M, DeJongste M, Diwan S, Eldabe S, Gatzinsky K, Foreman RD, Hayek S, Kim P, Kinfe T, Kloth D, Kumar K, Rizvi S, Lad SP, Liem L, Linderoth B, Mackey S, McDowell G, McRoberts P, Poree L, Prager J, Raso L, Rauck R, Russo M, Simpson B, Slavin K, Staats P, Stanton-Hicks M, Verrills P, Wellington J, Williams K, North R.
Neuromodulation. 2014 Aug;17(6):515-50; discussion 550. doi: 10.1111/ner.12208.
PMID: 25112889 [PubMed – in process]
Related citations
10.Effects of transcutaneous electrical nerve stimulation in patients with peripheral and central neuropathic pain.
K?l?nç M, Livanelio?lu A, Y?ld?r?m SA, Tan E.
J Rehabil Med. 2014 May;46(5):454-60. doi: 10.2340/16501977-1271.
PMID: 24549206 [PubMed – indexed for MEDLINE]
Related citations
11.Electrical stimulation as an adjunctive treatment of painful and sensory diabetic neuropathy.
Thakral G, Kim PJ, LaFontaine J, Menzies R, Najafi B, Lavery LA.
J Diabetes Sci Technol. 2013 Sep 1;7(5):1202-9. Review.
PMID: 24124947 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations
12.Electrical stimulation accelerates nerve regeneration and functional recovery in delayed peripheral nerve injury in rats.
Huang J, Zhang Y, Lu L, Hu X, Luo Z.
Eur J Neurosci. 2013 Dec;38(12):3691-701. doi: 10.1111/ejn.12370. Epub 2013 Oct 10.
PMID: 24118464 [PubMed – indexed for MEDLINE]
Related citations
13.Electrical stimulation for promoting peripheral nerve regeneration.
Haastert-Talini K, Grothe C.
Int Rev Neurobiol. 2013;109:111-24. doi: 10.1016/B978-0-12-420045-6.00005-5. Review.
PMID: 24093609 [PubMed – indexed for MEDLINE]
Related citations
14.The brain networks encoding visceral sensation in patients with gastrointestinal symptoms due to diabetic neuropathy.
Lelic D, Brock C, Simrén M, Frøkjaer JB, Søfteland E, Dimcevski G, Gregersen H, Drewes AM.
Neurogastroenterol Motil. 2014 Jan;26(1):46-58.
PMID: 24050116 [PubMed – indexed for MEDLINE]
Related citations
15.Electroacupuncture for chemotherapy-induced peripheral neuropathy: study protocol for a pilot multicentre randomized, patient-assessor-blinded, controlled trial.
Kim JH, Kim EJ, Seo BK, Lee S, Lee S, Jung SY, Lee MH, Kim AR, Park HJ, Shin MS, Choi SM.
Trials. 2013 Aug 14;14:254. doi: 10.1186/1745-6215-14-254.
PMID: 23945074 [PubMed – indexed for MEDLINE] Free PMC Article
Related citations
16.Objective assessment of C-fiber function by electrically induced axon reflex flare in patients with axonal and demyelinating polyneuropathy.
Kokotis P, Schmelz M, Papagianni AE, Zambelis T, Karandreas N.
J Clin Neurophysiol. 2013 Aug;30(4):422-7. doi: 10.1097/WNP.0b013e31829ddb97.
PMID: 23912584 [PubMed – indexed for MEDLINE]
Related citations
17.Electrical stimulation and electromagnetic field use in patients with diabetic neuropathy: systematic review and meta-analysis.
Stein C, Eibel B, Sbruzzi G, Lago PD, Plentz RD.
Braz J Phys Ther. 2013 Mar-Apr;17(2):93-104. doi: 10.1590/S1413-35552012005000083. Review.
PMID: 23778776 [PubMed – indexed for MEDLINE] Free Article
Related citations
18.An update on peripheral nerve stimulation.
Rasskazoff SY, Slavin KV.
J Neurosurg Sci. 2012 Dec;56(4):279-85. Review.
PMID: 23111288 [PubMed – indexed for MEDLINE]
Related citations
19.Functional electrical stimulation for bladder, bowel, and sexual function.
Creasey GH, Craggs MD.
Handb Clin Neurol. 2012;109:247-57. doi: 10.1016/B978-0-444-52137-8.00015-2. Review.
PMID: 23098717 [PubMed – indexed for MEDLINE]
Related citations
20.Pain and electrophysiological parameters are improved by combined 830-1064 high-intensity LASER in symptomatic carpal tunnel syndrome versus Transcutaneous Electrical Nerve Stimulation. A randomized controlled study.
Casale R, Damiani C, Maestri R, Wells CD.
Eur J Phys Rehabil Med. 2013 Apr;49(2):205-11. Epub 2012 Jul 20.
PMID: 22820819 [PubMed – indexed for MEDLINE] Free Article
Related citations

Leave a Comment

Your email address will not be published. Required fields are marked *

*