Fibromyalgia There is No Silver Bullet

Today we are discussing fibromyalgia. We have done many broadcasts on fibromyalgia relative to neurologic dysfunction and autoimmune problems. Today, we are aiming to bring all these topics together for a full picture so that the fibromyalgia patient can better understand their own symptoms and their pain.

Please enjoy, and send us your questions.  Please forward us any questions here on our website or go to our Power Health Facebook page
1.Fibromyalgia and non-celiac gluten sensitivity: a description with remission of fibromyalgia.
Isasi C, Colmenero I, Casco F, Tejerina E, Fernandez N, Serrano-Vela JI, Castro MJ, Villa LF.
Rheumatol Int. 2014 Nov;34(11):1607-12. doi: 10.1007/s00296-014-2990-6. Epub 2014 Apr 12.
PMID: 24728027 [PubMed – in process] Free PMC Article
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2.New diagnostic criteria for fibromyalgia: Here to stay?
Moyano S, Kilstein JG, Alegre de Miguel C.
Reumatol Clin. 2014 Oct 23. pii: S1699-258X(14)00173-9. doi: 10.1016/j.reuma.2014.07.008. [Epub ahead of print] English, Spanish.
PMID: 25443560 [PubMed – as supplied by publisher] Free Article
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3.[The association of fibromyalgia and systemic lupus erythematosus change the presentation and severity of both diseases?]
Araújo AL, Paliares IC, Araújo MI, Novo NF, Cadaval RA, Martinez JE.
Rev Bras Reumatol. 2014 Oct 16. pii: S0482-5004(14)00182-X. doi: 10.1016/j.rbr.2014.08.004. [Epub ahead of print] Portuguese.
PMID: 25435167 [PubMed – as supplied by publisher] Free Article
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4.The gut microbiome and the brain.
Galland L.
J Med Food. 2014 Dec;17(12):1261-72. doi: 10.1089/jmf.2014.7000.
PMID: 25402818 [PubMed – in process]
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5.Cytokine and chemokine profiles in fibromyalgia, rheumatoid arthritis and systemic lupus erythematosus: a potentially useful tool in differential diagnosis.
Wallace DJ, Gavin IM, Karpenko O, Barkhordar F, Gillis BS.
Rheumatol Int. 2014 Nov 7. [Epub ahead of print]
PMID: 25377646 [PubMed – as supplied by publisher]
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6.The prevalence of fibromyalgia in the general population: a comparison of the american college of rheumatology 1990, 2010, and modified 2010 classification criteria.
Jones GT, Atzeni F, Beasley M, Flüß E, Sarzi-Puttini P, Macfarlane GJ.
Arthritis Rheumatol. 2015 Feb;67(2):568-75. doi: 10.1002/art.38905.
PMID: 25323744 [PubMed – in process]
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7.Factors associated with tender point count in Puerto Ricans with fibromyalgia syndrome.
Ríos G, Estrada M, Mayor AM, Vilá LM.
P R Health Sci J. 2014 Sep;33(3):112-6.
PMID: 25244879 [PubMed – indexed for MEDLINE]
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8.Transcranial magnetic stimulation for chronic pain.
Young NA, Sharma M, Deogaonkar M.
Neurosurg Clin N Am. 2014 Oct;25(4):819-32. doi: 10.1016/ Epub 2014 Aug 12.
PMID: 25240669 [PubMed – in process]
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9.Microneurographic recording from unmyelinated nerve fibers in neurological disorders: An update.
Donadio V, Liguori R.
Clin Neurophysiol. 2014 Oct 17. pii: S1388-2457(14)00549-5. doi: 10.1016/j.clinph.2014.10.009. [Epub ahead of print] Review.
PMID: 25457652 [PubMed – as supplied by publisher]
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10.Reduction of Intraepidermal Nerve Fiber Density (IENFD) in the skin biopsies of patients with fibromyalgia: A controlled study.
Kosmidis ML, Koutsogeorgopoulou L, Alexopoulos H, Mamali I, Vlachoyiannopoulos PG, Voulgarelis M, Moutsopoulos HM, Tzioufas AG, Dalakas MC.
J Neurol Sci. 2014 Dec 15;347(1-2):143-7. doi: 10.1016/j.jns.2014.09.035. Epub 2014 Sep 28.
PMID: 25304055 [PubMed – in process]
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11.Small nerve fiber involvement in patients referred for fibromyalgia.
Giannoccaro MP, Donadio V, Incensi A, Avoni P, Liguori R.
Muscle Nerve. 2014 May;49(5):757-9. doi: 10.1002/mus.24156. Epub 2014 Jan 28.
PMID: 24469976 [PubMed – indexed for MEDLINE]
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12.Hyperexcitable C nociceptors in fibromyalgia.
Serra J, Collado A, Solà R, Antonelli F, Torres X, Salgueiro M, Quiles C, Bostock H.
Ann Neurol. 2014 Feb;75(2):196-208. doi: 10.1002/ana.24065. Epub 2014 Feb 12.
PMID: 24243538 [PubMed – indexed for MEDLINE]
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13.Objective evidence that small-fiber polyneuropathy underlies some illnesses currently labeled as fibromyalgia.
Oaklander AL, Herzog ZD, Downs HM, Klein MM.
Pain. 2013 Nov;154(11):2310-6. doi: 10.1016/j.pain.2013.06.001. Epub 2013 Jun 5.
PMID: 23748113 [PubMed – indexed for MEDLINE] Free PMC Article
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14.Small fibre pathology in patients with fibromyalgia syndrome.
Üçeyler N, Zeller D, Kahn AK, Kewenig S, Kittel-Schneider S, Schmid A, Casanova-Molla J, Reiners K, Sommer C.
Brain. 2013 Jun;136(Pt 6):1857-67. doi: 10.1093/brain/awt053. Epub 2013 Mar 9.
PMID: 23474848 [PubMed – indexed for MEDLINE] Free Article
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15.Chronic pain as a manifestation of potassium channel-complex autoimmunity.
Klein CJ, Lennon VA, Aston PA, McKeon A, Pittock SJ.
Neurology. 2012 Sep 11;79(11):1136-44. doi: 10.1212/WNL.0b013e3182698cab. Epub 2012 Aug 15.
PMID: 22895588 [PubMed – indexed for MEDLINE] Free PMC Article
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16.Central sensitization in fibromyalgia? A systematic review on structural and functional brain MRI.
Cagnie B, Coppieters I, Denecker S, Six J, Danneels L, Meeus M.
Semin Arthritis Rheum. 2014 Aug;44(1):68-75. doi: 10.1016/j.semarthrit.2014.01.001. Epub 2014 Jan 8.
PMID: 24508406 [PubMed – in process]
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17.Attentional bias toward negative information in patients with fibromyalgia syndrome.
Duschek S, Werner NS, Limbert N, Winkelmann A, Montoya P.
Pain Med. 2014 Apr;15(4):603-12. doi: 10.1111/pme.12360. Epub 2014 Jan 21.
PMID: 24447855 [PubMed – indexed for MEDLINE]
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18.Fibromyalgia and chronic widespread pain in autoimmune thyroid disease.
Ahmad J, Tagoe CE.
Clin Rheumatol. 2014 Jul;33(7):885-91. doi: 10.1007/s10067-014-2490-9. Epub 2014 Jan 18.
PMID: 24435355 [PubMed – in process]
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19.Segmental hyperalgesia to mechanical stimulus in interstitial cystitis/bladder pain syndrome: evidence of central sensitization.
Lai HH, Gardner V, Ness TJ, Gereau RW 4th.
J Urol. 2014 May;191(5):1294-9. doi: 10.1016/j.juro.2013.11.099. Epub 2013 Dec 6.
PMID: 24316091 [PubMed – indexed for MEDLINE]
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20.Structural alterations in brainstem of fibromyalgia syndrome patients correlate with sensitivity to mechanical pressure.
Fallon N, Alghamdi J, Chiu Y, Sluming V, Nurmikko T, Stancak A.
Neuroimage Clin. 2013 Aug 9;3:163-70. doi: 10.1016/j.nicl.2013.07.011. eCollection 2013.
PMID: 24179860 [PubMed] Free PMC Article
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21.Clinical endocannabinoid deficiency (CECD) revisited: can this concept explain the therapeutic benefits of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions?
Smith SC, Wagner MS.
Neuro Endocrinol Lett. 2014;35(3):198-201. Review.
PMID: 24977967 [PubMed – indexed for MEDLINE]
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22.A novel comparative effectiveness study of Tai Chi versus aerobic exercise for fibromyalgia: study protocol for a randomized controlled trial.
Wang C, McAlindon T, Fielding RA, Harvey WF, Driban JB, Price L, Kalish R, Schmid A, Scott TM, Schmid CH.
Trials. 2015 Jan 30;16(1):34. [Epub ahead of print]
PMID: 25633475 [PubMed – as supplied by publisher] Free Article
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23.Metals as a common trigger of inflammation resulting in non-specific symptoms: diagnosis and treatment.
Stejskal V.
Isr Med Assoc J. 2014 Dec;16(12):753-8.
PMID: 25630203 [PubMed – in process] Free Article
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24.Disinhibition of the primary somatosensory cortex in patients with fibromyalgia.
Lim M, Roosink M, Kim JS, Kim DJ, Kim HW, Lee EB, Kim HA, Chung CK.
Pain. 2015 Jan 27. [Epub ahead of print]
PMID: 25630027 [PubMed – as supplied by publisher]
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25.Mindfulness training for reducing anger, anxiety, and depression in fibromyalgia patients.
Amutio A, Franco C, Pérez-Fuentes Mde C, Gázquez JJ, Mercader I.
Front Psychol. 2015 Jan 12;5:1572. doi: 10.3389/fpsyg.2014.01572. eCollection 2014.
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26.Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin or pregabalin in fibromyalgia.
Kim SC, Landon JE, Lee YC.
Arthritis Res Ther. 2015 Jan 28;17(1):18. [Epub ahead of print]
PMID: 25627453 [PubMed – as supplied by publisher]
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27.[Gait characteristics of women with fibromyalgia: a premature aging pattern].
Góes SM, Leite N, de Souza RM, Homann D, Osiecki AC, Stefanello JM, Rodacki AL.
Rev Bras Reumatol. 2014 Sep-Oct;54(5):335-41. doi: 10.1016/j.rbr.2013.11.003. Epub 2014 Jul 6. Portuguese.
PMID: 25627295 [PubMed – in process] Free Article
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28.[Characterization of the pain, sleep and alexithymia patterns of patients with fibromyalgia treated in a Brazilian tertiary center].
Avila LA, de Araujo Filho GM, Guimarães EF, Gonçalves LC, Paschoalin PN, Aleixo FB.
Rev Bras Reumatol. 2014 Sep-Oct;54(5):409-13. doi: 10.1016/j.rbr.2014.03.017. Epub 2014 Jul 6. Portuguese.
PMID: 25627308 [PubMed – in process] Free Article
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29.The somatosensory link: S1 functional connectivity is altered by sustained pain and associated with clinical/autonomic dysfunction in fibromyalgia.
Kim J, Loggia ML, Cahalan CM, Harris RE, Beissner F, Garcia RG, Kim H, Wasan AD, Edwards RR, Napadow V.
Arthritis Rheumatol. 2015 Jan 26. doi: 10.1002/art.39043. [Epub ahead of print]
PMID: 25622796 [PubMed – as supplied by publisher]
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30.Rheumatic symptoms in autoimmune thyroiditis.
Tagoe CE.
Curr Rheumatol Rep. 2015 Feb;17(2):479. doi: 10.1007/s11926-014-0479-7.
PMID: 25618571 [PubMed – in process]
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31.Attenuation of autoimmune responses to oxidative specific epitopes, but not nitroso-adducts, is associated with a better clinical outcome in Myalgic Encephalomyelitis/chronic fatigue syndrome.
Maes M, Leunis JC.
Neuro Endocrinol Lett. 2014 Dec 24;35(7):577-585. [Epub ahead of print]
PMID: 25617880 [PubMed – as supplied by publisher]
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32.Evidence supporting a link between dental amalgams and chronic illness, fatigue, depression, anxiety, and suicide.
Kern JK, Geier DA, Bjørklund G, King PG, Homme KG, Haley BE, Sykes LK, Geier MR.
Neuro Endocrinol Lett. 2014 Dec 24;35(7):537-552. [Epub ahead of print]
PMID: 25617876 [PubMed – as supplied by publisher]
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33.What has functional connectivity and chemical neuroimaging in fibromyalgia taught us about the mechanisms and management of ‘centralized’ pain?
Napadow V, Harris RE.
Arthritis Res Ther. 2014;16(5):425.
PMID: 25606591 [PubMed – in process] Free PMC Article
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34.Gluten-free diet in the management of patients with irritable bowel syndrome, fibromyalgia and lymphocytic enteritis.
Volta U.
Arthritis Res Ther. 2014 Dec 23;16(6):505. doi: 10.1186/s13075-014-0505-1.
PMID: 25602179 [PubMed – in process] Free PMC Article
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35.Transcranial direct current stimulation as a treatment for patients with fibromyalgia: a randomized controlled trial.
Fagerlund AJ, Hansen OA, Aslaksen PM.
Pain. 2015 Jan;156(1):62-71. doi: 10.1016/j.pain.0000000000000006.
PMID: 25599302 [PubMed – in process]
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36.Soluble fractalkine in the plasma of fibromyalgia patients.
Garcia JJ, Ortega E.
An Acad Bras Cienc. 2014 Dec;86(4):1915-7. doi: 10.1590/0001-3765201420130081. Epub 2014 Dec 9.
PMID: 25590727 [PubMed – in process] Free Article
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37.Fibromyalgia Flares: A Qualitative Analysis.
Vincent A, Whipple MO, Rhudy LM.
Pain Med. 2015 Jan 13. doi: 10.1111/pme.12676. [Epub ahead of print]
PMID: 25586303 [PubMed – as supplied by publisher]
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38.Fibrofog and fibromyalgia: a narrative review and implications for clinical practice.
Kravitz HM, Katz RS.
Rheumatol Int. 2015 Jan 13. [Epub ahead of print]
PMID: 25583051 [PubMed – as supplied by publisher]
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39.Clinical Value of Serum Neuroplasticity Mediators in Identifying the Central Sensitivity Syndrome in Patients with Chronic Pain with and Without Structural Pathology.
Deitos A, Dussán-Sarria JA, de Souza A, Medeiros L, Tarragô MD, Sehn F, Chassot M, Zanette S, Schwertner A, Fregni F, Torres IL, Caumo W.
Clin J Pain. 2014 Dec 30. [Epub ahead of print]
PMID: 25551477 [PubMed – as supplied by publisher]
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40.Cognitive dysfunction in fibromyalgia: slow access to the mental lexicon.
Leavitt F, Katz RS.
Psychol Rep. 2014 Dec;115(3):828-39. doi: 10.2466/04.15.PR0.115c32z1.
PMID: 25539171 [PubMed – in process]
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