Autoimmune Diseases: Reason for the Dramatic Increase

Today we will be discussing the increasing prevalence of autoimmune disease, the literature regarding this issue, and our clinical opinion as to why the prevalence of autoimmune diseases is increasing so rapidly.

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References:
1. The microbiome and autoimmune disease: Report from a Noel R. Rose Colloquium.
Barin JG, Tobias LD, Peterson DA.
Clin Immunol. 2015 Aug;159(2):183-8. doi: 10.1016/j.clim.2015.05.009. Epub 2015 May 20.
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2. Autoantibodies in pre-clinical autoimmune disease.
Hu ZD, Deng AM.
Clin Chim Acta. 2014 Nov 1;437:14-8. doi: 10.1016/j.cca.2014.06.015. Epub 2014 Jun 24. Review.
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4. Inflammatory Bowel Disease and the Risk of Autoimmune Diseases.
Wilson JC, Furlano RI, Jick SS, Meier CR.
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Moghadam-Kia S, Franks AG Jr.
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7. Vitamin D in systemic and organ-specific autoimmune diseases.
Agmon-Levin N, Theodor E, Segal RM, Shoenfeld Y.
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8. The Link between Psychological Stress and Autoimmune Response in Children.
Faresjö M.
Crit Rev Immunol. 2015;35(2):117-34. Review.
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9. Triggers and drivers of autoimmunity: lessons from coeliac disease.
Sollid LM, Jabri B.
Nat Rev Immunol. 2013 Apr;13(4):294-302. doi: 10.1038/nri3407. Epub 2013 Mar 15. Review.
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10. [Gluten-related disorders and demyelinating diseases].
Hernández-Lahoz C, Rodrigo L.
Med Clin (Barc). 2013 Apr 15;140(7):314-9. doi: 10.1016/j.medcli.2012.07.009. Epub 2012 Sep 19. Review. Spanish.
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11. Gluten and wheat intolerance today: are modern wheat strains involved?
de Lorgeril M, Salen P.
Int J Food Sci Nutr. 2014 Aug;65(5):577-81. doi: 10.3109/09637486.2014.886185. Epub 2014 Feb 13.
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12. Non-celiac gluten sensitivity: Time for sifting the grain.
Elli L, Roncoroni L, Bardella MT.
World J Gastroenterol. 2015 Jul 21;21(27):8221-6. doi: 10.3748/wjg.v21.i27.8221. Review.
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13. Nonceliac gluten sensitivity.
Fasano A, Sapone A, Zevallos V, Schuppan D.
Gastroenterology. 2015 May;148(6):1195-204. doi: 10.1053/j.gastro.2014.12.049. Epub 2015 Jan 9. Review.
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14. Tissue transglutaminase antibodies in individuals with celiac disease bind to thyroid follicles and extracellular matrix and may contribute to thyroid dysfunction.
Naiyer AJ, Shah J, Hernandez L, Kim SY, Ciaccio EJ, Cheng J, Manavalan S, Bhagat G, Green PH.
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15. Effect of gliadin on permeability of intestinal biopsy explants from celiac disease patients and patients with non-celiac gluten sensitivity.
Hollon J, Puppa EL, Greenwald B, Goldberg E, Guerrerio A, Fasano A.
Nutrients. 2015 Feb 27;7(3):1565-76. doi: 10.3390/nu7031565.
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16. Non coeliac gluten sensitivity – A new disease with gluten intolerance.
Czaja-Bulsa G.
Clin Nutr. 2015 Apr;34(2):189-94. doi: 10.1016/j.clnu.2014.08.012. Epub 2014 Aug 29. Review.
PMID: 25245857 [PubMed – indexed for MEDLINE] Free Article
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17. Diagnosis of gluten related disorders: Celiac disease, wheat allergy and non-celiac gluten sensitivity.
Elli L, Branchi F, Tomba C, Villalta D, Norsa L, Ferretti F, Roncoroni L, Bardella MT.
World J Gastroenterol. 2015 Jun 21;21(23):7110-9. doi: 10.3748/wjg.v21.i23.7110. Review.
PMID: 26109797 [PubMed – indexed for MEDLINE] Free PMC Article
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